Higginbottom, Steven K.

Diet-induced extinctions in the gut microbiota compound over generations

Sonnenburg, E. D., Smits, S. A., Tikhonov, M., Higginbottom, S. K., Wingreen, N. S., & Sonnenburg, J. L. (2016) · Nature

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 1,730

A gut bacterial pathway metabolizes aromatic amino acids into nine circulating metabolites

Dodd, D., Spitzer, M. H., Van Treuren, W., Merrill, B. D., Hryckowian, A. J., Higginbottom, S. K., Le, A., Cowan, T. M., Nolan, G. P., Fischbach, M. A., et al. (2017) · Nature

Gut microbiota and healthTryptophan and brain disorders

Cited by 1,425

Microbiota-liberated host sugars facilitate post-antibiotic expansion of enteric pathogens

Ng, K. M., Ferreyra, J. A., Higginbottom, S. K., Lynch, J. B., Kashyap, P. C., Gopinath, S., Naidu, N., Choudhury, B., Weimer, B. C., Monack, D. M., et al. (2013) · Nature

Gut microbiota and healthClostridium difficile and Clostridium perfringens research

Cited by 1,035

A metabolic pathway for bile acid dehydroxylation by the gut microbiome

Funabashi, M., Grove, T. L., Wang, M., Varma, Y., McFadden, M. E., Brown, L. C., Guo, C., Higginbottom, S., Almo, S. C., & Fischbach, M. A. (2020) · Nature

Steroid Chemistry and BiochemistryMicrobial Natural Products and Biosynthesis

Cited by 590

Complex interactions among diet, gastrointestinal transit, and gut microbiota in humanized mice

Kashyap, P. C., Marcobal, A., Ursell, L. K., Larauche, M., Duboc, H., Earle, K. A., Sonnenburg, E. D., Ferreyra, J. A., Higginbottom, S. K., Million, M., et al. (2013) · Gastroenterology

Gut microbiota and healthGastrointestinal motility and disorders

Cited by 451

Genetically dictated change in host mucus carbohydrate landscape exerts a diet-dependent effect on the gut microbiota

Kashyap, P. C., Marcobal, A., Ursell, L. K., Smits, S. A., Sonnenburg, E. D., Costello, E. K., Higginbottom, S. K., Domino, S. E., Holmes, S. P., Relman, D. A., et al. (2013) · Proceedings of the National Academy of Sciences

Gut microbiota and healthMicrobial Metabolites in Food Biotechnology

Cited by 285

Mapping the T cell repertoire to a complex gut bacterial community

Nagashima, K., Zhao, A., Atabakhsh, K., Weakley, A., Jain, S., Meng, X., Cheng, A. G., Wang, M., Higginbottom, S., Dimas, A., et al. (2022) · Nature

T-cell and B-cell ImmunologyGut microbiota and health

Cited by 79

Genome-scale resources in the infant gut symbiont Bifidobacterium breve reveal genetic determinants of colonization and host-microbe interactions

Shiver, A. L., Sun, J., Culver, R., Violette, A., Wynter, C., Nieckarz, M., Mattiello, S. P., Sekhon, P. K., Bottacini, F., Friess, L., et al. (2025) · Cell

Gut microbiota and healthProbiotics and Fermented Foods

Cited by 27