Cited by 285Gut microbiota and healthMicrobial Metabolites in Food BiotechnologyInfant Nutrition and Health

Genetically dictated change in host mucus carbohydrate landscape exerts a diet-dependent effect on the gut microbiota

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Kashyap, Purna C., Marcobal, Angela, Ursell, Luke K., Smits, Samuel A., Sonnenburg, Erica D., Costello, Elizabeth K., Higginbottom, Steven K., Domino, Steven E. +5 more·2013·Proceedings of the National Academy of Sciences

Abstract

Significance: Our data demonstrate that differences in host genotype that affect the carbohydrate landscape of the distal gut interact with diet to alter the composition and function of resident microbes in a diet-dependent manner.

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Crossref · 10.1073/pnas.1306070110

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  • Differences in host genotype that affect the carbohydrate landscape of the distal gut interact with diet to alter the composition and function of resident microbes in a diet-dependent manner.

    “differences in host genotype, which affect the carbohydrate landscape of the distal gut, interact with diet to alter the composition and function of resident microbes in a diet-dependent manner.103”

    From The gut microbiota and host health: a new clinical frontier (2016) · cites this paper as [103]

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Authors
Kashyap, P. C., Marcobal, A., Ursell, L. K., Smits, S. A., Sonnenburg, E. D., Costello, E. K., Higginbottom, S. K., Domino, S. E., Holmes, S. P., Relman, D. A., Knight, R., Gordon, J. I., & Sonnenburg, J. L.
Affiliations
  • Mayo Clinic (US)
  • Stanford Medicine (US)
  • Howard Hughes Medical Institute (US)
  • University of Michigan (US)
  • Stanford University (US)
  • VA Palo Alto Health Care System (US)
  • Washington University in St. Louis (US)
Venue
Proceedings of the National Academy of Sciences
Published
2013-09-23
Volume
110
Issue
42
Pages
17059-17064
ISSN
  • 0027-8424 (ISSN-L)
  • 1091-6490
OpenAlex
W1989848555
Cited by
285
References
43
Citations by year
2026: 8 · 2025: 13 · 2024: 14 · 2023: 37 · 2022: 23 · 2021: 26 · 2020: 20 · 2019: 15 · 2018: 18 · 2017: 19 · 2016: 26 · 2015: 27 · 2014: 36 · 2013: 2
FWCI
13.58
Type
journal article
Language
en
Open access
Locations
  • Proceedings of the National Academy of Sciences (publishedVersion)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • eScholarship (California Digital Library) (submittedVersion)
Funders
  • National Science Foundation
  • Howard Hughes Medical Institute
  • Crohn's and Colitis Foundation of America
  • Crohn's and Colitis Foundation
  • National Institutes of Health (DGE-114747, DP1OD000964)
  • National Institute of General Medical Sciences (R01GM086884, GM86884, T32GM008759, T32GM142607)
  • National Institute of Diabetes and Digestive and Kidney Diseases (R37DK030292, DK-30292, DK085025, P30DK084567, R01DK030292, R01DK085025)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Gut microbiota and health
  • Health Sciences › Nursing › Nutrition and Dietetics › Microbial Metabolites in Food Biotechnology
  • Health Sciences › Nursing › Nutrition and Dietetics › Infant Nutrition and Health
Keywords
gut microbiota, fucosyltransferase, Bacteroides thetaiotaomicron, host-microbe interactions, fecal metabolites
MeSH terms
Galactoside 2-alpha-L-fucosyltransferase, Animals, Bacteroides, Dietary Carbohydrates, Fucosyltransferases, Glucans, Humans, Intestinal Mucosa, Mice, Knockout, Mice, Microbiota

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