Vinken, Mathieu

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME

Godoy, P., Hewitt, N. J., Albrecht, U., Andersen, M. E., Ansari, N., Bhattacharya, S., Bode, J. G., Bolleyn, J., Borner, C., Böttger, J., et al. (2013) · Archives of Toxicology

Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology

Cited by 1,280

Adverse outcome pathways: opportunities, limitations and open questions

Leist, M., Ghallab, A., Graepel, R., Marchan, R., Hassan, R., Bennekou, S. H., Limonciel, A., Vinken, M., Schildknecht, S., Waldmann, T., et al. (2017) · Archives of Toxicology

Animal testing and alternativesAgricultural safety and regulations

Cited by 394

Molecular Mechanisms Underlying the Dedifferentiation Process of Isolated Hepatocytes and Their Cultures

Elaut, G., Henkens, T., Papeleu, P., Snykers, S., Vinken, M., Vanhaecke, T., & Rogiers, V. (2006) · Current Drug Metabolism

Liver physiology and pathologyDrug-Induced Hepatotoxicity and Protection

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Primary hepatocyte cultures for pharmaco-toxicological studies: at the busy crossroad of various anti-dedifferentiation strategies

Fraczek, J., Bolleyn, J., Vanhaecke, T., Rogiers, V., & Vinken, M. (2013) · Archives of Toxicology

Drug-Induced Hepatotoxicity and ProtectionAnimal testing and alternatives

Cited by 119

Osteopontin characterizes bile duct–associated macrophages and correlates with liver fibrosis severity in primary sclerosing cholangitis

De Muynck, K., Heyerick, L., De Ponti, F. F., Vanderborght, B., Meese, T., Van Campenhout, S., Baudonck, L., Gijbels, E., Rodrigues, P. M., Banales, J. M., et al. (2024) · Hepatology

Liver Diseases and ImmunityLiver physiology and pathology

Cited by 64

An overview of current practices for regulatory risk assessment with lessons learnt from cosmetics in the European Union

Arnesdotter, E., Rogiers, V., Vanhaecke, T., & Vinken, M. (2021) · Critical Reviews in Toxicology

Animal testing and alternativesContact Dermatitis and Allergies

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What is understood by animal-free research

Oredsson, S., Coecke, S., van der Valk, J., & Vinken, M. (2019) · Toxicology in Vitro

Animal testing and alternativesBiomedical Ethics and Regulation

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