McGuffin, Peter

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

The Wellcome Trust Case Control Consortium, Management Committee, Burton, P. R., Clayton, D. G., Cardon, L. R., Craddock, N., Deloukas, P., Duncanson, A., Kwiatkowski, D. P., McCarthy, M. I., et al. (2007) · Nature

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 9,442

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

eQTLGen, Wray, N. R., 23andMe, the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Ripke, S., Mattheisen, M., Trzaskowski, M., Byrne, E. M., Abdellaoui, A., Adams, M. J., et al. (2018) · Nature Genetics

Genetic Associations and EpidemiologyTreatment of Major Depression

Cited by 3,005

A Polydiagnostic Application of Operational Criteria in Studies of Psychotic Illness: Development and Reliability of the OPCRIT System

McGuffin, P. (1991) · Archives of General Psychiatry

Schizophrenia research and treatmentReliability and Agreement in Measurement

Cited by 1,483

Large-scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4

Psychiatric GWAS Consortium Bipolar Disorder Working Group, Sklar, P., Ripke, S., Scott, L. J., Andreassen, O. A., Cichon, S., Craddock, N., Edenberg, H. J., Nurnberger, J. I., Rietschel, M., et al. (2011) · Nature Genetics

Bipolar Disorder and TreatmentGenetic Associations and Epidemiology

Cited by 1,344

Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

Wellcome Trust Case Control Consortium, Ferreira, M. A. R., O'Donovan, M. C., Meng, Y. A., Jones, I. R., Ruderfer, D. M., Jones, L., Fan, J., Kirov, G., Perlis, R. H., et al. (2008) · Nature Genetics

Bipolar Disorder and TreatmentGenetic Associations and Epidemiology

Cited by 1,237

A mega-analysis of genome-wide association studies for major depressive disorder

Major Depressive Disorder Working Group of the Psychiatric GWAS Consortium, Ripke, S., Wray, N. R., Lewis, C. M., Hamilton, S. P., Weissman, M. M., Breen, G., Byrne, E. M., Blackwood, D. H. R., Boomsma, D. I., et al. (2013) · Molecular Psychiatry

Genetic Associations and EpidemiologyBipolar Disorder and Treatment

Cited by 1,120

Gene–environment interaction analysis of serotonin system markers with adolescent depression

Eley, T. C., Sugden, K., Corsico, A., Gregory, A. M., Sham, P., McGuffin, P., Plomin, R., & Craig, I. W. (2004) · Molecular Psychiatry

Neurotransmitter Receptor Influence on BehaviorGenetic Associations and Epidemiology

Cited by 663

Meta-analysis and imputation refines the association of 15q25 with smoking quantity

The Wellcome Trust Case Control Consortium, Liu, J. Z., Tozzi, F., Waterworth, D. M., Pillai, S. G., Muglia, P., Middleton, L., Berrettini, W., Knouff, C. W., Yuan, X., et al. (2010) · Nature Genetics

Genetic Associations and EpidemiologySmoking Behavior and Cessation

Cited by 614

The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia

Wellcome Trust Case Control Consortium, Green, E. K., Grozeva, D., Jones, I., Jones, L., Kirov, G., Caesar, S., Gordon-Smith, K., Fraser, C., Forty, L., et al. (2010) · Molecular Psychiatry

Bipolar Disorder and TreatmentGenetic Associations and Epidemiology

Cited by 526

A Twin Study of Genetic Relationships Between Psychotic Symptoms

Cardno, A. G., Rijsdijk, F. V., Sham, P. C., Murray, R. M., & McGuffin, P. (2002) · American Journal of Psychiatry

Schizophrenia research and treatmentBipolar Disorder and Treatment

Cited by 460

Rare loss-of-function variants in SETD1A are associated with schizophrenia and developmental disorders

Study, S. S., Singh, T., Study, I., Study, D., UK10 K Consortium, Kurki, M. I., Curtis, D., Purcell, S. M., Crooks, L., McRae, J., et al. (2016) · Nature Neuroscience

Schizophrenia research and treatmentGenomics and Rare Diseases

Cited by 452

Genome-wide association study of major depressive disorder: new results, meta-analysis, and lessons learned

Wray, N. R., Pergadia, M. L., Blackwood, D. H. R., Penninx, B. W. J. H., Gordon, S. D., Nyholt, D. R., Ripke, S., MacIntyre, D. J., McGhee, K. A., Maclean, A. W., et al. (2012) · Molecular Psychiatry

Genetic Associations and EpidemiologyTreatment of Major Depression

Cited by 444

Candidate Genes Expression Profile Associated with Antidepressants Response in the GENDEP Study: Differentiating between Baseline ‘Predictors’ and Longitudinal ‘Targets’

Cattaneo, A., Gennarelli, M., Uher, R., Breen, G., Farmer, A., Aitchison, K. J., Craig, I. W., Anacker, C., Zunsztain, P. A., McGuffin, P., et al. (2013) · Neuropsychopharmacology

Treatment of Major DepressionTryptophan and brain disorders

Cited by 436

Reliability and Comparability of Psychosis Patients' Retrospective Reports of Childhood Abuse

Fisher, H. L., Craig, T. K., Fearon, P., Morgan, K., Dazzan, P., Lappin, J., Hutchinson, G., Doody, G. A., Jones, P. B., McGuffin, P., et al. (2011) · Schizophrenia Bulletin

Child Abuse and TraumaSchizophrenia research and treatment

Cited by 422

An Inflammatory Biomarker as a Differential Predictor of Outcome of Depression Treatment With Escitalopram and Nortriptyline

Uher, R., Tansey, K. E., Dew, T., Maier, W., Mors, O., Hauser, J., Dernovsek, M. Z., Henigsberg, N., Souery, D., Farmer, A., et al. (2014) · American Journal of Psychiatry

Treatment of Major DepressionTryptophan and brain disorders

Cited by 418

Fecundity of patients with schizophrenia, autism, bipolar disorder, depression, anorexia nervosa, or substance abuse vs their unaffected siblings

Power, R. A., Kyaga, S., Uher, R., MacCabe, J. H., Långström, N., Landen, M., McGuffin, P., Lewis, C. M., Lichtenstein, P., & Svensson, A. C. (2013) · JAMA Psychiatry

Schizophrenia research and treatmentGenetic Associations and Epidemiology

Cited by 336

Hippocampal atrophy in first episode depression: A meta-analysis of magnetic resonance imaging studies

Cole, J., Costafreda, S. G., McGuffin, P., & Fu, C. H. Y. (2011) · Journal of Affective Disorders

Treatment of Major DepressionStress Responses and Cortisol

Cited by 319

Interaction between stress and the BDNFVal66Met polymorphism in depression: a systematic review and meta-analysis

Hosang, G. M., Shiles, C., Tansey, K. E., McGuffin, P., & Uher, R. (2014) · BMC Medicine

Neurotransmitter Receptor Influence on BehaviorGenetic Associations and Epidemiology

Cited by 292

Association between C-reactive protein (CRP) with depression symptom severity and specific depressive symptoms in major depression

Köhler-Forsberg, O., Buttenschøn, H. N., Tansey, K. E., Maier, W., Hauser, J., Dernovsek, M. Z., Henigsberg, N., Souery, D., Farmer, A., Rietschel, M., et al. (2017) · Brain Behavior and Immunity

Tryptophan and brain disordersTreatment of Major Depression

Cited by 283

GWAS of Suicide Attempt in Psychiatric Disorders and Association With Major Depression Polygenic Risk Scores

Mullins, N., Bigdeli, T. B., Børglum, A. D., Coleman, J. R. I., Demontis, D., Mehta, D., Power, R. A., Ripke, S., Stahl, E. A., Starnawska, A., et al. (2019) · American Journal of Psychiatry

Suicide and Self-Harm StudiesGenetic Associations and Epidemiology

Cited by 270

Validity of the shortened Mood and Feelings Questionnaire in a community sample of children and adolescents: A preliminary research note

Thapar, A., & McGuffin, P. (1998) · Psychiatry Research

Child and Adolescent Psychosocial and Emotional DevelopmentAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cited by 268

Genetic predictors of response to antidepressants in the GENDEP project

Uher, R., Huezo-Diaz, P., Perroud, N., Smith, R., Rietschel, M., Mors, O., Hauser, J., Maier, W., Kozel, D., Henigsberg, N., et al. (2009) · The Pharmacogenomics Journal

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 226

Family dysfunction interacts with genes in the causation of antisocial symptoms

Button, T. M. M., Scourfield, J., Martin, N., Purcell, S., & McGuffin, P. (2005) · Behavior Genetics

Child and Adolescent Psychosocial and Emotional DevelopmentPsychopathy, Forensic Psychiatry, Sexual Offending

Cited by 171

Neuroticism, extraversion, life events and depression

Farmer, A., Redman, K., Harris, T., Mahmood, A., Sadler, S., Pickering, A., & McGuffin, P. (2002) · British Journal of Psychiatry

Personality Traits and PsychologyAnxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Cited by 170