Wittenberg, Gayle M.

Immune targets for therapeutic development in depression: towards precision medicine

Drevets, W. C., Wittenberg, G. M., Bullmore, E. T., & Manji, H. K. (2022) · Nature Reviews Drug Discovery

Tryptophan and brain disordersTreatment of Major Depression

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CSF1R inhibitor JNJ-40346527 attenuates microglial proliferation and neurodegeneration in P301S mice

Mancuso, R., Fryatt, G., Cleal, M., Obst, J., Pipi, E., Monzón-Sandoval, J., Ribe, E., Winchester, L., Webber, C., Nevado, A., et al. (2019) · Brain

Neuroinflammation and Neurodegeneration MechanismsAlzheimer's disease research and treatments

Cited by 235

MicroRNAs 146a/b-5 and 425-3p and 24-3p are markers of antidepressant response and regulate MAPK/Wnt-system genes

Lopez, J. P., Fiori, L. M., Cruceanu, C., Lin, R., Labonte, B., Cates, H. M., Heller, E. A., Vialou, V., Ku, S. M., Gerald, C., et al. (2017) · Nature Communications

Treatment of Major DepressionMicroRNA in disease regulation

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The effects of interleukin-6 neutralizing antibodies on symptoms of depressed mood and anhedonia in patients with rheumatoid arthritis and multicentric Castleman’s disease

Sun, Y., Wang, D., Salvadore, G., Hsu, B., Curran, M., Casper, C., Vermeulen, J., Kent, J. M., Singh, J., Drevets, W. C., et al. (2017) · Brain, Behavior, and Immunity

Rheumatoid Arthritis Research and TherapiesTryptophan and brain disorders

Cited by 100

The Role of Anxious Distress in Immune Dysregulation in Patients with Major Depressive Disorder

Gaspersz, R., Lamers, F., Wittenberg, G., Beekman, A. T. F., van Hemert, A. M., Schoevers, R. A., & Penninx, B. W. J. H. (2017) · Translational Psychiatry

Tryptophan and brain disordersStress Responses and Cortisol

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Clinical relevance of sleep duration: results from a cross-sectional analysis using NHANES

Cepeda, M. S., Stang, P., Blacketer, C., Kent, J. M., & Wittenberg, G. M. (2016) · Journal of Clinical Sleep Medicine

Sleep and related disordersSleep and Work-Related Fatigue

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Pharmacological modulation of TSPO in microglia/macrophages and neurons in a chronic neurodegenerative model of prion disease

Vicente-Rodríguez, M., Mancuso, R., Peris-Yague, A., Simmons, C., NIMA Consortium, Wlazly, D., Dickinson, A., Foster, A., Knight, C., Leckey, C., et al. (2023) · Journal of Neuroinflammation

Neuroinflammation and Neurodegeneration MechanismsPrion Diseases and Protein Misfolding

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Towards an AI biomedical scientist: Accelerating discoveries in neurodegenerative disease

Roberts, K. F., Landsness, E. C., Reese, J., Elbert, D., Strobel, G., Wu, E., Chen, Y., Lai, A., Abrams, Z. B., Zhu, M., et al. (2026) · The Journal of Prevention of Alzheimer's Disease

Artificial Intelligence in Healthcare and EducationArtificial Intelligence Applications

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