Kayagaki, Nobuhiko

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

Kayagaki, N., Stowe, I. B., Lee, B. L., O’Rourke, K., Anderson, K., Warming, S., Cuellar, T., Haley, B., Roose-Girma, M., Phung, Q. T., et al. (2015) · Nature

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 3,686

Non-canonical inflammasome activation targets caspase-11

Kayagaki, N., Warming, S., Lamkanfi, M., Walle, L. V., Louie, S., Dong, J., Newton, K., Qu, Y., Liu, J., Heldens, S., et al. (2011) · Nature

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 2,530

IAP Antagonists Induce Autoubiquitination of c-IAPs, NF-κB Activation, and TNFα-Dependent Apoptosis

Varfolomeev, E., Blankenship, J. W., Wayson, S. M., Fedorova, A. V., Kayagaki, N., Garg, P., Zobel, K., Dynek, J. N., Elliott, L. O., Wallweber, H. J. A., et al. (2007) · Cell

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 1,218

GsdmD p30 elicited by caspase-11 during pyroptosis forms pores in membranes

Aglietti, R. A., Estevez, A., Gupta, A., Ramirez, M. G., Liu, P. S., Kayagaki, N., Ciferri, C., Dixit, V. M., & Dueber, E. C. (2016) · Proceedings of the National Academy of Sciences

Inflammasome and immune disordersCell death mechanisms and regulation

Cited by 898

NINJ1 mediates plasma membrane rupture during lytic cell death

Kayagaki, N., Kornfeld, O. S., Lee, B. L., Stowe, I. B., O’Rourke, K., Li, Q., Sandoval, W., Yan, D., Kang, J., Xu, M., et al. (2021) · Nature

Cell death mechanisms and regulationInflammasome and immune disorders

Cited by 857

Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1

Broz, P., Ruby, T., Belhocine, K., Bouley, D. M., Kayagaki, N., Dixit, V. M., & Monack, D. M. (2012) · Nature

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 535

Caspase-11 activation requires lysis of pathogen-containing vacuoles by IFN-induced GTPases

Meunier, E., Dick, M. S., Dreier, R. F., Schürmann, N., Broz, D. K., Warming, S., Roose-Girma, M., Bumann, D., Kayagaki, N., Takeda, K., et al. (2014) · Nature

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 485

Selective activation of PFKL suppresses the phagocytic oxidative burst

Amara, N., Cooper, M. P., Voronkova, M. A., Webb, B. A., Lynch, E. M., Kollman, J. M., Ma, T., Yu, K., Lai, Z., Sangaraju, D., et al. (2021) · Cell

Neutrophil, Myeloperoxidase and Oxidative MechanismsRedox biology and oxidative stress

Cited by 158

Multiplexed, image-based pooled screens in primary cells and tissues with PerturbView

Kudo, T., Meireles, A. M., Moncada, R., Chen, Y., Wu, P., Gould, J., Hu, X., Kornfeld, O., Jesudason, R., Foo, C., et al. (2025) · Nature Biotechnology

Single-cell and spatial transcriptomicsCRISPR and Genetic Engineering

Cited by 74