Brenner, Steven E.

A large-scale evaluation of computational protein function prediction

Radivojac, P., Clark, W. T., Oron, T. R., Schnoes, A. M., Wittkop, T., Sokolov, A., Graim, K., Funk, C., Verspoor, K., Ben-Hur, A., et al. (2013) · Nature Methods

Bioinformatics and Genomic NetworksMachine Learning in Bioinformatics

Cited by 1,028

SCOPe: Structural Classification of Proteins--extended, integrating SCOP and ASTRAL data and classification of new structures

Fox, N. K., Brenner, S. E., & Chandonia, J.-M. (2014) · Nucleic Acids Research

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 762

Biases in Illumina transcriptome sequencing caused by random hexamer priming

Hansen, K. D., Brenner, S. E., & Dudoit, S. (2010) · Nucleic Acids Research

Genomics and Phylogenetic StudiesGene expression and cancer classification

Cited by 713

The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens

Zhou, N., Jiang, Y., Bergquist, T. R., Lee, A. J., Kacsoh, B. Z., Crocker, A. W., Lewis, K. A., Georghiou, G., Nguyen, H. N., Hamid, M. N., et al. (2019) · Genome Biology

Bioinformatics and Genomic NetworksGenomics and Phylogenetic Studies

Cited by 452

An unappreciated role for RNA surveillance

Hillman, R. T., Green, R. E., & Brenner, S. E. (2004) · Genome Biology

RNA Research and SplicingRNA regulation and disease

Cited by 193

Distribution of Protein Folds in the Three Superkingdoms of Life

Wolf, Y. I., Brenner, S. E., Bash, P. A., & Koonin, E. V. (1999) · Genome Research

Protein Structure and DynamicsGenomics and Phylogenetic Studies

Cited by 183

Opportunities and challenges for the computational interpretation of rare variation in clinically important genes

McInnes, G., Sharo, A. G., Koleske, M. L., Brown, J. E. H., Norstad, M., Adhikari, A. N., Wang, S., Brenner, S. E., Halpern, J., Koenig, B. A., et al. (2021) · The American Journal of Human Genetics

Genomics and Rare DiseasesArtificial Intelligence in Healthcare and Education

Cited by 86

Genome-wide Analysis of Alternative Pre-mRNA Splicing and RNA-Binding Specificities of the Drosophila hnRNP A/B Family Members

Blanchette, M., Green, R. E., MacArthur, S., Brooks, A. N., Brenner, S. E., Eisen, M. B., & Rio, D. C. (2009) · Molecular Cell

RNA Research and SplicingRNA regulation and disease

Cited by 86

VIPdb, a genetic variant impact predictor database

Hu, Z., Yu, C., Furutsuki, M., Andreoletti, G., Ly, M., Hoskins, R., Adhikari, A. N., & Brenner, S. E. (2019) · Human Mutation

Genomics and Rare DiseasesGenetic Associations and Epidemiology

Cited by 37