McBride, David J.

Massive genomic rearrangement acquired in a single catastrophic event during cancer development

Stephens, P. J., Greenman, C. D., Fu, B., Yang, F., Bignell, G. R., Mudie, L. J., Pleasance, E. D., Lau, K. W., Beare, D., Stebbings, L. A., et al. (2011) · Cell

Cancer Genomics and DiagnosticsGenomic variations and chromosomal abnormalities

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Mutational Processes Molding the Genomes of 21 Breast Cancers

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Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer

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A comprehensive catalogue of somatic mutations from a human cancer genome

Pleasance, E. D., Cheetham, R. K., Stephens, P. J., McBride, D. J., Humphray, S. J., Greenman, C. D., Varela, I., Lin, M.-L., Ordóñez, G. R., Bignell, G. R., et al. (2010) · Nature

Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer

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The Life History of 21 Breast Cancers

Nik-Zainal, S., Van Loo, P., Wedge, D. C., Alexandrov, L. B., Greenman, C. D., Lau, K. W., Raine, K., Jones, D., Marshall, J., Ramakrishna, M., et al. (2012) · Cell

Cancer Genomics and DiagnosticsCancer Cells and Metastasis

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The patterns and dynamics of genomic instability in metastatic pancreatic cancer

Campbell, P. J., Yachida, S., Mudie, L. J., Stephens, P. J., Pleasance, E. D., Stebbings, L. A., Morsberger, L. A., Latimer, C., McLaren, S., Lin, M.-L., et al. (2010) · Nature

Cancer Genomics and DiagnosticsPancreatic and Hepatic Oncology Research

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Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

Dalgliesh, G. L., Furge, K., Greenman, C., Chen, L., Bignell, G., Butler, A., Davies, H., Edkins, S., Hardy, C., Latimer, C., et al. (2010) · Nature

Renal cell carcinoma treatmentChromatin Remodeling and Cancer

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Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer

van Haaften, G., Dalgliesh, G. L., Davies, H., Chen, L., Bignell, G., Greenman, C., Edkins, S., Hardy, C., O'Meara, S., Teague, J., et al. (2009) · Nature Genetics

Epigenetics and DNA MethylationChromatin Remodeling and Cancer

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A phase II trial of mTORC1/2 inhibition in STK11 deficient non small cell lung cancer

Middleton, G., Robbins, H. L., Fletcher, P., Savage, J., Mehmi, M., Summers, Y., Greystoke, A., Steele, N., Popat, S., Jain, P., et al. (2025) · npj Precision Oncology

Lung Cancer Treatments and MutationsPI3K/AKT/mTOR signaling in cancer

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