Hannon, Gregory J.

twist is a potential oncogene that inhibits apoptosis

Maestro, R., Tos, A. P. D., Hamamori, Y., Krasnokutsky, S., Sartorelli, V., Kedes, L., Doglioni, C., Beach, D. H., & Hannon, G. J. (1999) · Genes & Development

Cancer-related Molecular PathwaysCell death mechanisms and regulation

Cited by 516

FAS and NF-κB signalling modulate dependence of lung cancers on mutant EGFR

Bivona, T. G., Hieronymus, H., Parker, J., Chang, K., Taron, M., Rosell, R., Moonsamy, P., Dahlman, K., Miller, V. A., Costa, C., et al. (2011) · Nature

Lung Cancer Treatments and MutationsHER2/EGFR in Cancer Research

Cited by 396

A biochemical approach to identifying microRNA targets

Karginov, F. V., Conaco, C., Xuan, Z., Schmidt, B. H., Parker, J. S., Mandel, G., & Hannon, G. J. (2007) · Proceedings of the National Academy of Sciences

MicroRNA in disease regulationRNA Interference and Gene Delivery

Cited by 371

The miRNA-Processing Enzyme Dicer Is Essential for the Morphogenesis and Maintenance of Hair Follicles

Andl, T., Murchison, E. P., Liu, F., Zhang, Y., Yunta-Gonzalez, M., Tobias, J. W., Andl, C. D., Seykora, J. T., Hannon, G. J., & Millar, S. E. (2006) · Current Biology

Hair Growth and DisordersMicroRNA in disease regulation

Cited by 359

miRNAs are essential for survival and differentiation of newborn neurons but not for expansion of neural progenitors during early neurogenesis in the mouse embryonic neocortex

De Pietri Tonelli, D., Pulvers, J. N., Haffner, C., Murchison, E. P., Hannon, G. J., & Huttner, W. B. (2008) · Development

Neurogenesis and neuroplasticity mechanismsMicroRNA in disease regulation

Cited by 343

An alternative mode of microRNA target recognition

Chi, S. W., Hannon, G. J., & Darnell, R. B. (2012) · Nature Structural & Molecular Biology

MicroRNA in disease regulationRNA Research and Splicing

Cited by 328

A Rapid and Scalable System for Studying Gene Function in Mice Using Conditional RNA Interference

Premsrirut, P. K., Dow, L. E., Kim, S. Y., Camiolo, M., Malone, C. D., Miething, C., Scuoppo, C., Zuber, J., Dickins, R. A., Kogan, S. C., et al. (2011) · Cell

RNA Interference and Gene DeliveryAnimal Genetics and Reproduction

Cited by 315

Oncogenic ras and p53 Cooperate To Induce Cellular Senescence

Ferbeyre, G., de Stanchina, E., Lin, A. W., Querido, E., McCurrach, M. E., Hannon, G. J., & Lowe, S. W. (2002) · Molecular and Cellular Biology

Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways

Cited by 290

Mutations associated with familial melanoma impair p16INK4 function

Ranade, K., Hussussian, C. J., Sikorski, R. S., Varmus, H. E., Goldstein, A. M., Tucker, M. A., Serrano, M., Hannon, G. J., Beach, D., & Dracopoli, N. C. (1995) · Nature Genetics

Cancer-related Molecular PathwaysCutaneous Melanoma Detection and Management

Cited by 280

Cell-Type-Based Analysis of MicroRNA Profiles in the Mouse Brain

He, M., Liu, Y., Wang, X., Zhang, M. Q., Hannon, G. J., & Huang, Z. J. (2012) · Neuron

MicroRNA in disease regulationRNA regulation and disease

Cited by 277

A Transcriptome-wide RNAi Screen in the Drosophila Ovary Reveals Factors of the Germline piRNA Pathway

Czech, B., Preall, J. B., McGinn, J., & Hannon, G. J. (2013) · Molecular Cell

Chromosomal and Genetic VariationsRNA Interference and Gene Delivery

Cited by 269

Mutational landscape of EGFR- , MYC- , and Kras- driven genetically engineered mouse models of lung adenocarcinoma

McFadden, D. G., Politi, K., Bhutkar, A., Chen, F. K., Song, X., Pirun, M., Santiago, P. M., Kim-Kiselak, C., Platt, J. T., Lee, E., et al. (2016) · Proceedings of the National Academy of Sciences

Cancer Genomics and DiagnosticsLung Cancer Treatments and Mutations

Cited by 194

Tissue-specific and reversible RNA interference in transgenic mice

Dickins, R. A., McJunkin, K., Hernando, E., Premsrirut, P. K., Krizhanovsky, V., Burgess, D. J., Kim, S. Y., Cordon-Cardo, C., Zender, L., Hannon, G. J., et al. (2007) · Nature Genetics

RNA Interference and Gene DeliveryAnimal Genetics and Reproduction

Cited by 174

Design of 240,000 orthogonal 25mer DNA barcode probes

Xu, Q., Schlabach, M. R., Hannon, G. J., & Elledge, S. J. (2009) · Proceedings of the National Academy of Sciences

Gene expression and cancer classificationAdvanced biosensing and bioanalysis techniques

Cited by 170

A pipeline for the generation of shRNA transgenic mice

Dow, L. E., Premsrirut, P. K., Zuber, J., Fellmann, C., McJunkin, K., Miething, C., Park, Y., Dickins, R. A., Hannon, G. J., & Lowe, S. W. (2012) · Nature Protocols

RNA Interference and Gene DeliveryCRISPR and Genetic Engineering

Cited by 159

Transformation of normal human cells in the absence of telomerase activation

Seger, Y. R., Garcı́a-Cao, M., Piccinin, S., Cunsolo, C. L., Doglioni, C., Blasco, M. A., Hannon, G. J., & Maestro, R. (2002) · Cancer Cell

Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways

Cited by 159

Drosophila H1 Regulates the Genetic Activity of Heterochromatin by Recruitment of Su(var)3-9

Lu, X., Wontakal, S. N., Kavi, H., Kim, B. J., Guzzardo, P. M., Emelyanov, A. V., Xu, N., Hannon, G. J., Zavadil, J., Fyodorov, D. V., et al. (2013) · Science

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 105

Two ancient human genomes reveal Polynesian ancestry among the indigenous Botocudos of Brazil

Malaspinas, A.-S., Lao, O., Schroeder, H., Rasmussen, M., Raghavan, M., Moltke, I., Campos, P. F., Sagredo, F. S., Rasmussen, S., Gonçalves, V. F., et al. (2014) · Current Biology

Forensic and Genetic ResearchGenetic diversity and population structure

Cited by 98

Cyfip1 is a putative invasion suppressor in epithelial cancers

Silva, J. M., Ezhkova, E., Silva, J., Heart, S., Castillo, M., Campos, Y., Castro, V., Bonilla, F., Cordon-Cardo, C., Muthuswamy, S. K., et al. (2009) · Cell

Mechanisms of cancer metastasisCellular Mechanics and Interactions

Cited by 87

Targeted resequencing of a genomic region influencing tameness and aggression reveals multiple signals of positive selection

Albert, F. W., Hodges, E., Jensen, J. D., Besnier, F., Xuan, Z., Rooks, M., Bhattacharjee, A., Brizuela, L., Good, J. M., Green, R. E., et al. (2011) · Heredity

Genetic and phenotypic traits in livestockGenetic Mapping and Diversity in Plants and Animals

Cited by 28

Defined genetic events associated with the spontaneous in vitro transformation of ElA/Ras-expressing human IMR90 fibroblasts

Mason, D. X., Keppler, D., Zhang, J., Jackson, T. J., Seger, Y. R., Matsui, S., Abreo, F., Cowell, J. K., Hannon, G. J., Lowe, S. W., et al. (2006) · Carcinogenesis

Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways

Cited by 18

Erratum: Asparagine bioavailability governs metastasis in a model of breast cancer

Knott, S. R. V., Wagenblast, E., Khan, S., Kim, S. Y., Soto, M., Wagner, M., Turgeon, M.-O., Fish, L., Erard, N., Gable, A. L., et al. (2018) · Nature

Amino Acid Enzymes and MetabolismCancer, Hypoxia, and Metabolism

Cited by 12