Sigrist, Stephan J.

Cardioprotection and lifespan extension by the natural polyamine spermidine

Eisenberg, T., Abdellatif, M., Schroeder, S., Primessnig, U., Stekovic, S., Pendl, T., Harger, A., Schipke, J., Zimmermann, A., Schmidt, A., et al. (2016) · Nature Medicine

Polyamine Metabolism and ApplicationsGenetics, Aging, and Longevity in Model Organisms

Cited by 1,168

Bruchpilot, a protein with homology to ELKS/CAST, is required for structural integrity and function of synaptic active zones in Drosophila

Wagh, D. A., Rasse, T. M., Asan, E., Hofbauer, A., Schwenkert, I., Dürrbeck, H., Buchner, S., Dabauvalle, M.-C., Schmidt, M., Qin, G., et al. (2006) · Neuron

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 908

Bruchpilot Promotes Active Zone Assembly, Ca 2+ Channel Clustering, and Vesicle Release

Kittel, R. J., Wichmann, C., Rasse, T. M., Fouquet, W., Schmidt, M., Schmid, A., Wagh, D. A., Pawlu, C., Kellner, R. R., Willig, K. I., et al. (2006) · Science

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 772

Chronological aging leads to apoptosis in yeast

Herker, E., Jungwirth, H., Lehmann, K. A., Maldener, C., Fröhlich, K.-U., Wissing, S., Büttner, S., Fehr, M., Sigrist, S., & Madeo, F. (2004) · The Journal of Cell Biology

Genetics, Aging, and Longevity in Model OrganismsCell death mechanisms and regulation

Cited by 548

Endonuclease G Regulates Budding Yeast Life and Death

Büttner, S., Eisenberg, T., Carmona-Gutierrez, D., Ruli, D., Knauer, H., Ruckenstuhl, C., Sigrist, C., Wissing, S., Kollroser, M., Fröhlich, K.-U., et al. (2007) · Molecular Cell

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 331

RIM-Binding Protein, a Central Part of the Active Zone, Is Essential for Neurotransmitter Release

Liu, K. S. Y., Siebert, M., Mertel, S., Knoche, E., Wegener, S., Wichmann, C., Matkovic, T., Muhammad, K., Depner, H., Mettke, C., et al. (2011) · Science

Cellular transport and secretionNeuroscience and Neuropharmacology Research

Cited by 306

Nucleocytosolic depletion of the energy metabolite acetyl-coenzyme a stimulates autophagy and prolongs lifespan

Eisenberg, T., Schroeder, S., Andryushkova, A., Pendl, T., Küttner, V., Bhukel, A., Mariño, G., Pietrocola, F., Harger, A., Zimmermann, A., et al. (2014) · Cell Metabolism

Autophagy in Disease and TherapyGenetics, Aging, and Longevity in Model Organisms

Cited by 256

Dietary spermidine improves cognitive function

Schroeder, S., Hofer, S. J., Zimmermann, A., Pechlaner, R., Dammbrueck, C., Pendl, T., Marcello, G. M., Pogatschnigg, V., Bergmann, M., Müller, M., et al. (2021) · Cell Reports

Genetics, Aging, and Longevity in Model OrganismsPolyamine Metabolism and Applications

Cited by 225

A Syd-1 homologue regulates pre- and postsynaptic maturation in Drosophila

Owald, D., Fouquet, W., Schmidt, M., Wichmann, C., Mertel, S., Depner, H., Christiansen, F., Zube, C., Quentin, C., Körner, J., et al. (2010) · Journal of Cell Biology

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 191

Endonuclease G mediates α‐synuclein cytotoxicity during Parkinson's disease

Büttner, S., Habernig, L., Broeskamp, F., Ruli, D., Vögtle, F. N., Vlachos, M., Macchi, F., Küttner, V., Carmona‐Gutierrez, D., Eisenberg, T., et al. (2013) · The EMBO Journal

Parkinson's Disease Mechanisms and TreatmentsNuclear Receptors and Signaling

Cited by 87

Spermidine-triggered autophagy ameliorates memory during aging

Sigrist, S. J., Carmona-Gutierrez, D., Gupta, V. K., Bhukel, A., Mertel, S., Eisenberg, T., & Madeo, F. (2014) · Autophagy

Genetics, Aging, and Longevity in Model OrganismsPolyamine Metabolism and Applications

Cited by 82

Rapid Ca 2+ channel accumulation contributes to cAMP-mediated increase in transmission at hippocampal mossy fiber synapses

Fukaya, R., Maglione, M., Sigrist, S. J., & Sakaba, T. (2021) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchIon channel regulation and function

Cited by 42

Unc13A and Unc13B contribute to the decoding of distinct sensory information in Drosophila

Pooryasin, A., Maglione, M., Schubert, M., Matkovic-Rachid, T., Hasheminasab, S.-M., Pech, U., Fiala, A., Mielke, T., & Sigrist, S. J. (2021) · Nature Communications

Neuroscience and Neuropharmacology ResearchNeurobiology and Insect Physiology Research

Cited by 35

Recruitment of release sites underlies chemical presynaptic potentiation at hippocampal mossy fiber boutons

Orlando, M., Dvorzhak, A., Bruentgens, F., Maglione, M., Rost, B. R., Sigrist, S. J., Breustedt, J., & Schmitz, D. (2021) · PLOS Biology

Neuroscience and Neuropharmacology ResearchCellular transport and secretion

Cited by 30