Karlseder, Jan

p53- and ATM-Dependent Apoptosis Induced by Telomeres Lacking TRF2

Karlseder, J., Broccoli, D., Dai, Y., Hardy, S., & de Lange, T. (1999) · Science

Telomeres, Telomerase, and SenescenceCell death mechanisms and regulation

Cited by 1,086

Mammalian Telomeres Resemble Fragile Sites and Require TRF1 for Efficient Replication

Sfeir, A., Kosiyatrakul, S. T., Hockemeyer, D., MacRae, S. L., Karlseder, J., Schildkraut, C. L., & de Lange, T. (2009) · Cell

Telomeres, Telomerase, and SenescenceDNA Repair Mechanisms

Cited by 990

Senescence Induced by Altered Telomere State, Not Telomere Loss

Karlseder, J., Smogorzewska, A., & de Lange, T. (2002) · Science

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 796

Replication and protection of telomeres

Verdun, R. E., & Karlseder, J. (2007) · Nature

Telomeres, Telomerase, and SenescenceDNA Repair Mechanisms

Cited by 463

Autophagic cell death restricts chromosomal instability during replicative crisis

Nassour, J., Radford, R., Correia, A., Fusté, J. M., Schoell, B., Jauch, A., Shaw, R. J., & Karlseder, J. (2019) · Nature

Autophagy in Disease and TherapyTelomeres, Telomerase, and Senescence

Cited by 429

Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres

O'Sullivan, R. J., Kubicek, S., Schreiber, S. L., & Karlseder, J. (2010) · Nature Structural & Molecular Biology

Telomeres, Telomerase, and SenescenceGenomics and Chromatin Dynamics

Cited by 416

Regulation of DNA repair pathway choice in S and G2 phases by the NHEJ inhibitor CYREN

Arnoult, N., Correia, A., Ma, J., Merlo, A., Garcia-Gomez, S., Maric, M., Tognetti, M., Benner, C. W., Boulton, S. J., Saghatelian, A., et al. (2017) · Nature

DNA Repair MechanismsEffects of Radiation Exposure

Cited by 299

Functional Human Telomeres Are Recognized as DNA Damage in G2 of the Cell Cycle

Verdun, R. E., Crabbe, L., Haggblom, C., & Karlseder, J. (2005) · Molecular Cell

Telomeres, Telomerase, and SenescenceDNA Repair Mechanisms

Cited by 284

Telomere dysfunction as a cause of genomic instability in Werner syndrome

Crabbe, L., Jauch, A., Naeger, C. M., Holtgreve-Grez, H., & Karlseder, J. (2007) · Proceedings of the National Academy of Sciences

Telomeres, Telomerase, and SenescenceDNA Repair Mechanisms

Cited by 240

The Telomere Deprotection Response Is Functionally Distinct from the Genomic DNA Damage Response

Cesare, A. J., Hayashi, M. T., Crabbe, L., & Karlseder, J. (2013) · Molecular Cell

Telomeres, Telomerase, and SenescenceDNA Repair Mechanisms

Cited by 155

Cell death during crisis is mediated by mitotic telomere deprotection

Hayashi, M. T., Cesare, A. J., Rivera, T., & Karlseder, J. (2015) · Nature

Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways

Cited by 125

A three-state model of telomere control over human proliferative boundaries

Cesare, A. J., & Karlseder, J. (2012) · Current Opinion in Cell Biology

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 106

A genomics approach identifies senescence‐specific gene expression regulation

Lackner, D. H., Hayashi, M. T., Cesare, A. J., & Karlseder, J. (2014) · Aging Cell

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 47