Bernard, David

The Polycomb group protein EZH2 directly controls DNA methylation

Viré, E., Brenner, C., Deplus, R., Blanchon, L., Fraga, M., Didelot, C., Morey, L., Van Eynde, A., Bernard, D., Vanderwinden, J.-M., et al. (2006) · Nature

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 2,204

Chemokine signaling via the CXCR2 receptor reinforces senescence

Acosta, J. C., O'Loghlen, A., Banito, A., Guijarro, M. V., Augert, A., Raguz, S., Fumagalli, M., Da Costa, M., Brown, C., Popov, N., et al. (2008) · Cell

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 1,801

Polycomb CBX7 has a unifying role in cellular lifespan.

Gil, J., Bernard, D., Martínez, D., & Beach, D. (2004) · Nature Cell Biology

Telomeres, Telomerase, and SenescenceEpigenetics and DNA Methylation

Cited by 341

A High Glycolytic Flux Supports the Proliferative Potential of Murine Embryonic Stem Cells

Kondoh, H., Lleonart, M. E., Nakashima, Y., Yokode, M., Tanaka, M., Bernard, D., Gil, J., & Beach, D. (2007) · Antioxidants & Redox Signaling

Cancer, Hypoxia, and MetabolismPluripotent Stem Cells Research

Cited by 325

Endoplasmic reticulum calcium release through ITPR2 channels leads to mitochondrial calcium accumulation and senescence

Wiel, C., Lallet-Daher, H., Gitenay, D., Gras, B., Le Calvé, B., Augert, A., Ferrand, M., Prevarskaya, N., Simonnet, H., Vindrieux, D., et al. (2014) · Nature Communications

Telomeres, Telomerase, and SenescenceMitochondrial Function and Pathology

Cited by 231

Histone variant H2A.J accumulates in senescent cells and promotes inflammatory gene expression

Contrepois, K., Coudereau, C., Benayoun, B. A., Schuler, N., Roux, P.-F., Bischof, O., Courbeyrette, R., Carvalho, C., Thuret, J.-Y., Ma, Z., et al. (2017) · Nature Communications

Telomeres, Telomerase, and SenescenceGenomics and Chromatin Dynamics

Cited by 191

Eliminating Senescent Cells Can Promote Pulmonary Hypertension Development and Progression

Born, E., Lipskaia, L., Breau, M., Houssaini, A., Beaulieu, D., Marcos, E., Pierre, R., Do Cruzeiro, M., Lefevre, M., Derumeaux, G., et al. (2023) · Circulation

Pulmonary Hypertension Research and TreatmentsTelomeres, Telomerase, and Senescence

Cited by 148

Regulation of ploidy and senescence by the AMPK‐related kinase NUAK1

Humbert, N., Navaratnam, N., Augert, A., Da Costa, M., Martien, S., Wang, J., Martinez, D., Abbadie, C., Carling, D., de Launoit, Y., et al. (2010) · The EMBO Journal

Telomeres, Telomerase, and SenescenceHippo pathway signaling and YAP/TAZ

Cited by 115

Transcriptional repression of DNA repair genes is a hallmark and a cause of cellular senescence

Collin, G., Huna, A., Warnier, M., Flaman, J.-M., & Bernard, D. (2018) · Cell Death & Disease

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 71

DNA methylation protects cancer cells against senescence

Chen, X., Yamaguchi, K., Rodgers, B., Goehrig, D., Vindrieux, D., Lahaye, X., Nolot, M., Ferry, L., Martin, N., Dubus, P., et al. (2024) · Nature Communications

Telomeres, Telomerase, and SenescenceEpigenetics and DNA Methylation

Cited by 17

DNA methylation protects cancer cells against senescence

Chen, X., Yamaguchi, K., Rodgers, B., Goehrig, D., Vindrieux, D., Lahaye, X., Nolot, M., Ferry, L., Lanciano, S., Martin, N., et al. (2025) · Nature Communications

Telomeres, Telomerase, and SenescenceEpigenetics and DNA Methylation

Cited by 17