Sommer, Lukas

Sox10 promotes the formation and maintenance of giant congenital naevi and melanoma

Shakhova, O., Zingg, D., Schaefer, S. M., Hari, L., Civenni, G., Blunschi, J., Claudinot, S., Okoniewski, M., Beermann, F., Mihic-Probst, D., et al. (2012) · Nature Cell Biology

Melanoma and MAPK Pathwaysmelanin and skin pigmentation

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Mouse Cutaneous Melanoma Induced by Mutant BRaf Arises from Expansion and Dedifferentiation of Mature Pigmented Melanocytes

Köhler, C., Nittner, D., Rambow, F., Radaelli, E., Stanchi, F., Vandamme, N., Baggiolini, A., Sommer, L., Berx, G., van den Oord, J. J., et al. (2017) · Cell Stem Cell

Melanoma and MAPK PathwaysCutaneous Melanoma Detection and Management

Cited by 126

Antagonistic Cross-Regulation between Sox9 and Sox10 Controls an Anti-tumorigenic Program in Melanoma

Shakhova, O., Cheng, P., Mishra, P. J., Zingg, D., Schaefer, S. M., Debbache, J., Häusel, J., Matter, C., Guo, T., Davis, S., et al. (2015) · PLOS Genetics

Melanoma and MAPK PathwaysCutaneous Melanoma Detection and Management

Cited by 111

Methylation-dependent SOX9 expression mediates invasion in human melanoma cells and is a negative prognostic factor in advanced melanoma

Cheng, P. F., Shakhova, O., Widmer, D. S., Eichhoff, O. M., Zingg, D., Frommel, S. C., Belloni, B., Raaijmakers, M. I., Goldinger, S. M., Santoro, R., et al. (2015) · Genome Biology

Epigenetics and DNA MethylationMelanoma and MAPK Pathways

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Persistent Wnt/β-catenin signaling determines dorsalization of the postnatal subventricular zone and neural stem cell specification into oligodendrocytes and glutamatergic neurons

Azim, K., Fischer, B., Hurtado‐Chong, A., Draganova, K., Cantù, C., Zemke, M., Sommer, L., Butt, A., & Raineteau, O. (2014) · Stem Cells

Neurogenesis and neuroplasticity mechanismsWnt/β-catenin signaling in development and cancer

Cited by 88

The low affinity neurotrophin receptor CD271 regulates phenotype switching in melanoma

Restivo, G., Diener, J., Cheng, P. F., Kiowski, G., Bonalli, M., Biedermann, T., Reichmann, E., Levesque, M. P., Dummer, R., & Sommer, L. (2017) · Nature Communications

Melanoma and MAPK PathwaysCutaneous Melanoma Detection and Management

Cited by 82

Yin Yang 1 Orchestrates a Metabolic Program Required for Both Neural Crest Development and Melanoma Formation

Varum, S., Baggiolini, A., Zurkirchen, L., Atak, Z. K., Cantù, C., Marzorati, E., Bossart, R., Wouters, J., Häusel, J., Tuncer, E., et al. (2019) · Cell Stem Cell

Developmental Biology and Gene RegulationMelanoma and MAPK Pathways

Cited by 65

Reemergence of neural crest stem cell-like states in melanoma during disease progression and treatment

Diener, J., & Sommer, L. (2021) · Stem Cells Translational Medicine

Cancer Cells and MetastasisMelanoma and MAPK Pathways

Cited by 64

Epigenetic control of melanoma cell invasiveness by the stem cell factor SALL4

Diener, J., Baggiolini, A., Pernebrink, M., Dalcher, D., Lerra, L., Cheng, P. F., Varum, S., Häusel, J., Stierli, S., Treier, M., et al. (2021) · Nature Communications

Melanoma and MAPK PathwaysEpigenetics and DNA Methylation

Cited by 34

Extracellular sodium regulates fibroblast growth factor 23 (FGF23) formation

Radvanyi, Z., Yoo, E. J., Kandasamy, P., Salas-Bastos, A., Monnerat, S., Refardt, J., Christ-Crain, M., Hayashi, H., Kondo, Y., Jantsch, J., et al. (2024) · Journal of Biological Chemistry

Parathyroid Disorders and TreatmentsBone Metabolism and Diseases

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