Okkenhaug, Klaus

Requirement of bic/microRNA-155 for Normal Immune Function

Rodriguez, A., Vigorito, E., Clare, S., Warren, M. V., Couttet, P., Soond, D. R., van Dongen, S., Grocock, R. J., Das, P. P., Miska, E. A., et al. (2007) · Science

MicroRNA in disease regulationT-cell and B-cell Immunology

Cited by 1,833

Ribosomal Protein S6 Kinase 1 Signaling Regulates Mammalian Life Span

Selman, C., Tullet, J. M. A., Wieser, D., Irvine, E., Lingard, S. J., Choudhury, A. I., Claret, M., Al-Qassab, H., Carmignac, D., Ramadani, F., et al. (2009) · Science

Genetics, Aging, and Longevity in Model OrganismsPI3K/AKT/mTOR signaling in cancer

Cited by 1,120

PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells

Finlay, D. K., Rosenzweig, E., Sinclair, L. V., Feijoo-Carnero, C., Hukelmann, J. L., Rolf, J., Panteleyev, A. A., Okkenhaug, K., & Cantrell, D. A. (2012) · Journal of Experimental Medicine

PI3K/AKT/mTOR signaling in cancerT-cell and B-cell Immunology

Cited by 596

Evidence for lifespan extension and delayed age–related biomarkers in insulin receptor substrate 1 null mice

Selman, C., Lingard, S., Choudhury, A. I., Batterham, R. L., Claret, M., Clements, M., Ramadani, F., Okkenhaug, K., Schuster, E., Blanc, E., et al. (2008) · The FASEB Journal

Genetics, Aging, and Longevity in Model OrganismsGrowth Hormone and Insulin-like Growth Factors

Cited by 532

Critical role for the p110α phosphoinositide-3-OH kinase in growth and metabolic regulation

Foukas, L. C., Claret, M., Pearce, W., Okkenhaug, K., Meek, S., Peskett, E., Sancho, S., Smith, A. J. H., Withers, D. J., & Vanhaesebroeck, B. (2006) · Nature

PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer

Cited by 463

Signaling by the Phosphoinositide 3-Kinase Family in Immune Cells

Okkenhaug, K. (2013) · Annual Review of Immunology

PI3K/AKT/mTOR signaling in cancerProtein Kinase Regulation and GTPase Signaling

Cited by 446

PI3Kδ and primary immunodeficiencies

Lucas, C. L., Chandra, A., Nejentsev, S., Condliffe, A. M., & Okkenhaug, K. (2016) · Nature Reviews Immunology

Immunodeficiency and Autoimmune DisordersT-cell and B-cell Immunology

Cited by 342

A point mutation in CD28 distinguishes proliferative signals from survival signals.

Okkenhaug, K., Wu, L., Garza, K. M., La Rose, J., Khoo, W., Odermatt, B., Mak, T. W., Ohashi, P. S., & Rottapel, R. (2001) · Nature Immunology

T-cell and B-cell ImmunologySignaling Pathways in Disease

Cited by 210

Phosphoinositide 3-kinase δ inhibition promotes antitumor responses but antagonizes checkpoint inhibitors

Lim, E. L., Cugliandolo, F. M., Rosner, D. R., Gyori, D., Roychoudhuri, R., & Okkenhaug, K. (2018) · JCI Insight

Cancer Immunotherapy and BiomarkersT-cell and B-cell Immunology

Cited by 66

Gut microbiota-derived hexa-acylated lipopolysaccharides enhance cancer immunotherapy responses

Sardar, P., Beresford-Jones, B. S., Xia, W., Shabana, O., Suyama, S., Ramos, R. J. F., Soderholm, A. T., Tourlomousis, P., Kuo, P., Evans, A. C., et al. (2025) · Nature Microbiology

Cancer Immunotherapy and BiomarkersGut microbiota and health

Cited by 49