Groß, Olaf

Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17

LeibundGut-Landmann, S., Groß, O., Robinson, M. J., Osorio, F., Slack, E. C., Tsoni, S. V., Schweighoffer, E., Tybulewicz, V., Brown, G. D., Ruland, J., et al. (2007) · Nature Immunology

Immune Response and InflammationImmunotherapy and Immune Responses

Cited by 1,191

Single-cell profiling identifies myeloid cell subsets with distinct fates during neuroinflammation

Jordão, M. J. C., Sankowski, R., Brendecke, S. M., Sagar, Locatelli, G., Tai, Y.-H., Tay, T. L., Schramm, E., Armbruster, S., Hagemeyer, N., et al. (2019) · Science

Neuroinflammation and Neurodegeneration MechanismsSingle-cell and spatial transcriptomics

Cited by 843

A Homozygous CARD9 Mutation in a Family with Susceptibility to Fungal Infections

Glocker, E.-O., Hennigs, A., Nabavi, M., Schäffer, A. A., Woellner, C., Salzer, U., Pfeifer, D., Veelken, H., Warnatz, K., Tahami, F., et al. (2009) · New England Journal of Medicine

Immunodeficiency and Autoimmune DisordersAntifungal resistance and susceptibility

Cited by 800

The inflammasome: an integrated view

Gross, O., Thomas, C. J., Guarda, G., & Tschopp, J. (2011) · Immunological Reviews

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 778

Inhibitor of Apoptosis Proteins Limit RIP3 Kinase-Dependent Interleukin-1 Activation

Vince, J. E., Wong, W. W.-L., Gentle, I., Lawlor, K. E., Allam, R., O'Reilly, L., Mason, K., Gross, O., Ma, S., Guarda, G., et al. (2012) · Immunity

Inflammasome and immune disordersCell death mechanisms and regulation

Cited by 491

Immune modulatory effects of oncogenic KRAS in cancer

Hamarsheh, S., Groß, O., Brummer, T., & Zeiser, R. (2020) · Nature Communications

Cancer Immunotherapy and BiomarkersProtein Kinase Regulation and GTPase Signaling

Cited by 387

The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes

Kasper, L., König, A., Koenig, P.-A., Gresnigt, M. S., Westman, J., Drummond, R. A., Lionakis, M. S., Groß, O., Ruland, J., Naglik, J. R., et al. (2018) · Nature Communications

Inflammasome and immune disordersAntifungal resistance and susceptibility

Cited by 297

XIAP Restricts TNF- and RIP3-Dependent Cell Death and Inflammasome Activation

Yabal, M., Müller, N., Adler, H., Knies, N., Groß, C. J., Damgaard, R. B., Kanegane, H., Ringelhan, M., Kaufmann, T., Heikenwälder, M., et al. (2014) · Cell Reports

Cell death mechanisms and regulationImmune Response and Inflammation

Cited by 255

Schistosoma mansoni triggers Dectin-2, which activates the Nlrp3 inflammasome and alters adaptive immune responses

Ritter, M., Gross, O., Kays, S., Ruland, J., Nimmerjahn, F., Saijo, S., Tschopp, J., Layland, L. E., & Prazeres da Costa, C. (2010) · Proceedings of the National Academy of Sciences

Inflammasome and immune disordersParasites and Host Interactions

Cited by 243