Guidotti, Alessandro

Reelin promoter hypermethylation in schizophrenia

Grayson, D. R., Jia, X., Chen, Y., Sharma, R. P., Mitchell, C. P., Guidotti, A., & Costa, E. (2005) · Proceedings of the National Academy of Sciences

Epigenetics and DNA MethylationSchizophrenia research and treatment

Cited by 553

Epigenetic modifications of GABAergic interneurons are associated with the schizophrenia-like phenotype induced by prenatal stress in mice

Matrisciano, F., Tueting, P., Dalal, I., Kadriu, B., Grayson, D. R., Davis, J. M., Nicoletti, F., & Guidotti, A. (2013) · Neuropharmacology

Epigenetics and DNA MethylationSchizophrenia research and treatment

Cited by 271

GABAergic dysfunction in schizophrenia: new treatment strategies on the horizon

Guidotti, A., Auta, J., Davis, J. M., Dong, E., Grayson, D. R., Veldic, M., Zhang, X., & Costa, E. (2005) · Psychopharmacology

Schizophrenia research and treatmentNeuroscience and Neuropharmacology Research

Cited by 262

Brain 5α-dihydroprogesterone and allopregnanolone synthesis in a mouse model of protracted social isolation

Dong, E., Matsumoto, K., Uzunova, V., Sugaya, I., Takahata, H., Nomura, H., Watanabe, H., Costa, E., & Guidotti, A. (2001) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchStress Responses and Cortisol

Cited by 261

Fluoxetine and norfluoxetine stereospecifically and selectively increase brain neurosteroid content at doses that are inactive on 5-HT reuptake

Pinna, G., Costa, E., & Guidotti, A. (2006) · Psychopharmacology

Neuroscience and Neuropharmacology ResearchTreatment of Major Depression

Cited by 245

Cortical bitufted, horizontal, and Martinotti cells preferentially express and secrete reelin into perineuronal nets, nonsynaptically modulating gene expression

Pesold, C., Liu, W. S., Guidotti, A., Costa, E., & Caruncho, H. J. (1999) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 160

Expression of reelin in adult mammalian blood, liver, pituitary pars intermedia, and adrenal chromaffin cells

Smalheiser, N. R., Costa, E., Guidotti, A., Impagnatiello, F., Auta, J., Lacor, P., Kriho, V., & Pappas, G. D. (2000) · Proceedings of the National Academy of Sciences

Axon Guidance and Neuronal SignalingDevelopmental Biology and Gene Regulation

Cited by 158

SSRIs act as selective brain steroidogenic stimulants (SBSSs) at low doses that are inactive on 5-HT reuptake

Pinna, G., Costa, E., & Guidotti, A. (2009) · Current Opinion in Pharmacology

Neuroscience and Neuropharmacology ResearchTreatment of Major Depression

Cited by 156

Increased binding of MeCP2 to the GAD1 and RELN promoters may be mediated by an enrichment of 5-hmC in autism spectrum disorder (ASD) cerebellum

Zhubi, A., Chen, Y., Dong, E., Cook, E. H., Guidotti, A., & Grayson, D. R. (2014) · Translational Psychiatry

Epigenetics and DNA MethylationGenetics and Neurodevelopmental Disorders

Cited by 154

Maternal immune activation induces GAD1 and GAD2 promoter remodeling in the offspring prefrontal cortex

Labouesse, M. A., Dong, E., Grayson, D. R., Guidotti, A., & Meyer, U. (2015) · Epigenetics

Epigenetics and DNA MethylationTryptophan and brain disorders

Cited by 138

Stimulation of Brain Pregnenolone Synthesis by Mitochondrial Diazepam Binding Inhibitor Receptor Ligands In Vivo

Korneyev, A., Pan, B. S., Polo, A., Romeo, E., Guidotti, A., & Costa, E. (1993) · Journal of Neurochemistry

Neuroscience and Neuropharmacology ResearchPharmacological Receptor Mechanisms and Effects

Cited by 132

Characterization of the action of antipsychotic subtypes on valproate-induced chromatin remodeling

Guidotti, A., Dong, E., Kundakovic, M., Satta, R., Grayson, D. R., & Costa, E. (2009) · Trends in Pharmacological Sciences

Schizophrenia research and treatmentEpigenetics and DNA Methylation

Cited by 130

Pharmacological activation of group-ii metabotropic glutamate receptors corrects a schizophrenia-like phenotype induced by prenatal stress in mice

Matrisciano, F., Tueting, P., Maccari, S., Nicoletti, F., & Guidotti, A. (2012) · Neuropsychopharmacology

Schizophrenia research and treatmentNeuroscience and Neuropharmacology Research

Cited by 110

Endogenous protein kinase inhibitors. Purification, characterization, and distribution in different tissues

Szmigielski, A., Guidotti, A., & Costa, E. (1977) · Journal of Biological Chemistry

Protein Kinase Regulation and GTPase SignalingBiochemical and Molecular Research

Cited by 92

Glutamic acid decarboxylase and glutamate receptor changes during tolerance and dependence to benzodiazepines

Izzo, E., Auta, J., Impagnatiello, F., Pesold, C., Guidotti, A., & Costa, E. (2001) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchEpilepsy research and treatment

Cited by 90

Advancing drug discovery for schizophrenia

Marder, S. R., Roth, B., Sullivan, P. F., Scolnick, E. M., Nestler, E. J., Geyer, M. A., Welnberger, D. R., Karayiorgou, M., Guidotti, A., Gingrich, J., et al. (2011) · Annals of the New York Academy of Sciences

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 25