McCorvy, John D.

PRESTO-Tango as an open-source resource for interrogation of the druggable human GPCRome

Kroeze, W. K., Sassano, M. F., Huang, X.-P., Lansu, K., McCorvy, J. D., Giguère, P. M., Sciaky, N., & Roth, B. L. (2015) · Nature Structural & Molecular Biology

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A non-hallucinogenic psychedelic analogue with therapeutic potential

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Psychedelics and Drug StudiesAlkaloids: synthesis and pharmacology

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In silico design of novel probes for the atypical opioid receptor MRGPRX2

Lansu, K., Karpiak, J., Liu, J., Huang, X.-P., McCorvy, J. D., Kroeze, W. K., Che, T., Nagase, H., Carroll, F. I., Jin, J., et al. (2017) · Nature Chemical Biology

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The anthelmintic praziquantel is a human serotoninergic G-protein-coupled receptor ligand

Chan, J. D., Cupit, P. M., Gunaratne, G. S., McCorvy, J. D., Yang, Y., Stoltz, K., Webb, T. R., Dosa, P. I., Roth, B. L., Abagyan, R., et al. (2017) · Nature Communications

Parasites and Host InteractionsReceptor Mechanisms and Signaling

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Mu-Opioid Receptor Selective Superagonists Produce Prolonged Respiratory Depression

Malcolm, N. J., Palkovic, B., Sprague, D. J., Calkins, M. M., Lanham, J. K., Halberstadt, A. L., Stucke, A. G., & McCorvy, J. D. (2023) · iScience

Receptor Mechanisms and SignalingNeuropeptides and Animal Physiology

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