Smyrk, Thomas

An Integrated TCGA Pan-Cancer Clinical Data Resource to Drive High-Quality Survival Outcome Analytics

Liu, J., Lichtenberg, T., Hoadley, K. A., Poisson, L. M., Lazar, A. J., Cherniack, A. D., Kovatich, A. J., Benz, C. C., Levine, D. A., Lee, A. V., et al. (2018) · Cell

Cancer Genomics and DiagnosticsGene expression and cancer classification

Cited by 3,725

Oncogenic Signaling Pathways in The Cancer Genome Atlas

Sanchez-Vega, F., Mina, M., Armenia, J., Chatila, W. K., Luna, A., La, K. C., Dimitriadoy, S., Liu, D. L., Kantheti, H. S., Saghafinia, S., et al. (2018) · Cell

Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer

Cited by 3,201

Cell-of-Origin Patterns Dominate the Molecular Classification of 10,000 Tumors from 33 Types of Cancer

Hoadley, K. A., Yau, C., Hinoue, T., Wolf, D. M., Lazar, A. J., Drill, E., Shen, R., Taylor, A. M., Cherniack, A. D., Thorsson, V., et al. (2018) · Cell

Cancer Genomics and DiagnosticsGene expression and cancer classification

Cited by 2,546

Comprehensive Characterization of Cancer Driver Genes and Mutations

Bailey, M. H., Tokheim, C., Porta-Pardo, E., Sengupta, S., Bertrand, D., Weerasinghe, A., Colaprico, A., Wendl, M. C., Kim, J., Reardon, B., et al. (2018) · Cell

Cancer Genomics and DiagnosticsGenomics and Rare Diseases

Cited by 2,256

Machine Learning Identifies Stemness Features Associated with Oncogenic Dedifferentiation

Malta, T. M., Sokolov, A., Gentles, A. J., Burzykowski, T., Poisson, L., Weinstein, J. N., Kamińska, B., Huelsken, J., Omberg, L., Gevaert, O., et al. (2018) · Cell

Cancer Cells and MetastasisPluripotent Stem Cells Research

Cited by 2,180

Integrated genomic characterization of pancreatic ductal adenocarcinoma

Raphael, B. J., Hruban, R. H., Aguirre, A. J., Moffitt, R. A., Yeh, J. J., Stewart, C., Robertson, A. G., Cherniack, A. D., Gupta, M., Getz, G., et al. (2017) · Cancer Cell

Pancreatic and Hepatic Oncology ResearchCancer Genomics and Diagnostics

Cited by 2,019

Immunoglobulin G4-associated cholangitis: clinical profile and response to therapy

Ghazale, A., Chari, S. T., Zhang, L., Smyrk, T. C., Takahashi, N., Levy, M. J., Topazian, M. D., Clain, J. E., Pearson, R. K., Petersen, B. T., et al. (2008) · Gastroenterology

IgG4-Related and Inflammatory DiseasesLiver Diseases and Immunity

Cited by 890

Comprehensive Characterization of Cancer Driver Genes and Mutations

Bailey, M. H., Tokheim, C., Porta-Pardo, E., Sengupta, S., Bertrand, D., Weerasinghe, A., Colaprico, A., Wendl, M. C., Kim, J., Reardon, B., et al. (2018) · Cell

Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer

Cited by 552

Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer

Wang, Y., Xu, X., Maglic, D., Dill, M. T., Mojumdar, K., Ng, P. K.-S., Jeong, K. J., Tsang, Y. H., Moreno, D., Bhavana, V. H., et al. (2018) · Cell Reports

Hippo pathway signaling and YAP/TAZCancer-related molecular mechanisms research

Cited by 500

Pan-cancer Alterations of the MYC Oncogene and Its Proximal Network across the Cancer Genome Atlas

Schaub, F. X., Dhankani, V., Berger, A. C., Trivedi, M., Richardson, A. B., Shaw, R., Zhao, W., Zhang, X., Ventura, A., Liu, Y., et al. (2018) · Cell Systems

Cancer Genomics and DiagnosticsCancer-related Molecular Pathways

Cited by 431

Perspective on Oncogenic Processes at the End of the Beginning of Cancer Genomics

Ding, L., Bailey, M. H., Porta-Pardo, E., Thorsson, V., Colaprico, A., Bertrand, D., Gibbs, D. L., Weerasinghe, A., Huang, K.-L., Tokheim, C., et al. (2018) · Cell

Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer

Cited by 399

Fasting blood glucose levels provide estimate of duration and progression of pancreatic cancer before diagnosis

Sharma, A., Smyrk, T. C., Levy, M. J., Topazian, M. A., & Chari, S. T. (2018) · Gastroenterology

Pancreatic and Hepatic Oncology ResearchPancreatic function and diabetes

Cited by 204

Alterations in mucosal immunity identified in the colon of patients with irritable bowel syndrome

Aerssens, J., Camilleri, M., Talloen, W., Thielemans, L., Göhlmann, H. W. H., Van den Wyngaert, I., Thielemans, T., De Hoogt, R., Andrews, C. N., Bharucha, A. E., et al. (2008) · Clinical Gastroenterology and Hepatology

Gastrointestinal motility and disordersGut microbiota and health

Cited by 124

Ultrastructural differences between diabetic and idiopathic gastroparesis

Faussone‐Pellegrini, M. S., Grover, M., Pasricha, P. J., Bernard, C. E., Lurken, M. S., Smyrk, T. C., Parkman, H. P., Abell, T. L., Snape, W. J., Hasler, W. L., et al. (2012) · Journal of Cellular and Molecular Medicine

Gastrointestinal motility and disordersGastroesophageal reflux and treatments

Cited by 123

Precancerous bile duct pathology in end-stage primary sclerosing cholangitis, with and without cholangiocarcinoma

Lewis, J. T., Talwalkar, J. A., Rosen, C. B., Smyrk, T. C., & Abraham, S. C. (2010) · American Journal of Surgical Pathology

Liver Diseases and ImmunityCholangiocarcinoma and Gallbladder Cancer Studies

Cited by 122

Stool DNA Testing for Screening Detection of Colorectal Neoplasia in Alaska Native People

Redwood, D. G., Asay, E. D., Blake, I. D., Sacco, P. E., Christensen, C. M., Sacco, F. D., Tiesinga, J. J., Devens, M. E., Alberts, S. R., Mahoney, D. W., et al. (2016) · Mayo Clinic Proceedings

Colorectal Cancer Screening and DetectionGenetic factors in colorectal cancer

Cited by 107

Detection of Colorectal Serrated Polyps by Stool DNA Testing: Comparison with Fecal Immunochemical Testing for Occult Blood (FIT)

Heigh, R. I., Yab, T. C., Taylor, W. R., Hussain, F. T. N., Smyrk, T. C., Mahoney, D. W., Domanico, M. J., Berger, B. M., Lidgard, G. P., & Ahlquist, D. A. (2014) · PLoS ONE

Colorectal Cancer Screening and DetectionGenetic factors in colorectal cancer

Cited by 75

Constipation-Predominant Irritable Bowel Syndrome Females Have Normal Colonic Barrier and Secretory Function

Peters, S. A., Edogawa, S., Sundt, W. J., Dyer, R. B., Dalenberg, D. A., Mazzone, A., Singh, R. J., Moses, N., Smyrk, T. C., Weber, C., et al. (2017) · American Journal of Gastroenterology

Gastrointestinal motility and disordersGut microbiota and health

Cited by 48

Long-term survival and prognostic indicators in small (≤2 cm) pancreatic cancer

Pongprasobchai, S., Pannala, R., Smyrk, T. C., Bamlet, W., Pitchumoni, S., Ougolkov, A., Andrade, M. D., Petersen, G. M., & Chari, S. T. (2008) · Pancreatology

Pancreatic and Hepatic Oncology ResearchCholangiocarcinoma and Gallbladder Cancer Studies

Cited by 36