Saunthararajah, Yogen

Aberrant DNA methylation is a dominant mechanism in MDS progression to AML

Jiang, Y., Dunbar, A., Gondek, L. P., Mohan, S., Rataul, M., O'Keefe, C., Sekeres, M., Saunthararajah, Y., & Maciejewski, J. P. (2009) · Blood

Acute Myeloid Leukemia ResearchEpigenetics and DNA Methylation

Cited by 384

Effects of 5-aza-2′-deoxycytidine on fetal hemoglobin levels, red cell adhesion, and hematopoietic differentiation in patients with sickle cell disease

Saunthararajah, Y., Hillery, C. A., Lavelle, D., Molokie, R., Dorn, L., Bressler, L., Gavazova, S., Chen, Y.-H., Hoffman, R., & DeSimone, J. (2003) · Blood

Hemoglobinopathies and Related DisordersBlood groups and transfusion

Cited by 277

Myelodysplastic syndrome and aplastic anemia: distinct entities or diseases linked by a common pathophysiology?

Barrett, J., Saunthararajah, Y., & Molldrem, J. (2000) · Seminars in Hematology

Acute Myeloid Leukemia ResearchBlood disorders and treatments

Cited by 207

Modification of hematopoietic stem cell fate by 5aza 2′deoxycytidine and trichostatin A.

Milhem, M., Mahmud, N., Lavelle, D., Araki, H., DeSimone, J., Saunthararajah, Y., & Hoffman, R. (2004) · Blood

Hematopoietic Stem Cell TransplantationEpigenetics and DNA Methylation

Cited by 195

Novel homo- and hemizygous mutations in EZH2 in myeloid malignancies

Makishima, H., Jankowska, A. M., Tiu, R. V., Szpurka, H., Sugimoto, Y., Hu, Z., Saunthararajah, Y., Guinta, K., Keddache, M. A., Putnam, P., et al. (2010) · Leukemia

Acute Myeloid Leukemia ResearchEpigenetics and DNA Methylation

Cited by 179

CpG methylation patterns and decitabine treatment response in acute myeloid leukemia cells and normal hematopoietic precursors

Negrotto, S., Ng, K. P., Jankowska, A. M., Bodo, J., Gopalan, B., Guinta, K., Mulloy, J. C., Hsi, E., Maciejewski, J., & Saunthararajah, Y. (2012) · Leukemia

Acute Myeloid Leukemia ResearchEpigenetics and DNA Methylation

Cited by 90

Key clinical observations after 5-azacytidine and decitabine treatment of myelodysplastic syndromes suggest practical solutions for better outcomes

Saunthararajah, Y. (2013) · Hematology

Acute Myeloid Leukemia ResearchEpigenetics and DNA Methylation

Cited by 79

p53 independent epigenetic-differentiation treatment in xenotransplant models of acute myeloid leukemia

Ng, K. P., Ebrahem, Q., Negrotto, S., Mahfouz, R. Z., Link, K. A., Hu, Z., Gu, X., Advani, A., Kalaycio, M., Sobecks, R., et al. (2011) · Leukemia

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

Cited by 68

RUNX1 regulates corepressor interactions of PU.1

Hu, Z., Gu, X., Baraoidan, K., Ibanez, V., Sharma, A., Kadkol, S., Munker, R., Ackerman, S., Nucifora, G., & Saunthararajah, Y. (2011) · Blood

Genomics and Chromatin DynamicsAcute Myeloid Leukemia Research

Cited by 63

Decitabine maintains hematopoietic precursor self-renewal by preventing repression of stem cell genes by a differentiation-inducing stimulus.

Hu, Z., Negrotto, S., Gu, X., Mahfouz, R., Ng, K. P., Ebrahem, Q., Copelan, E., Singh, H., Maciejewski, J. P., & Saunthararajah, Y. (2010) · Molecular Cancer Therapeutics

Hematopoietic Stem Cell TransplantationEpigenetics and DNA Methylation

Cited by 50

GSK-3 inhibition sensitizes acute myeloid leukemia cells to 1,25D-mediated differentiation

Gupta, K., Stefan, T., Ignatz-Hoover, J., Moreton, S., Parizher, G., Saunthararajah, Y., & Wald, D. N. (2016) · Cancer Research

Vitamin D Research StudiesAcute Myeloid Leukemia Research

Cited by 44

Runx1 regulation of Pu.1 corepressor/coactivator exchange identifies specific molecular targets for leukemia differentiation therapy

Gu, X., Hu, Z., Ebrahem, Q., Crabb, J. S., Mahfouz, R. Z., Radivoyevitch, T., Crabb, J. W., & Saunthararajah, Y. (2014) · Journal of Biological Chemistry

Genomics and Chromatin DynamicsAcute Myeloid Leukemia Research

Cited by 42

Polycomb segment myeloid malignancies

Saunthararajah, Y., & Maciejewski, J. (2012) · Blood

Acute Myeloid Leukemia ResearchEpigenetics and DNA Methylation

Cited by 12

Using PU.1 and Jun dimerization protein 2 transcription factor expression in myelodysplastic syndromes to predict treatment response and leukaemia transformation

Boasman, K., Simmonds, M. J., Graham, C., Saunthararajah, Y., & Rinaldi, C. R. (2019) · Annals of Hematology

Acute Myeloid Leukemia ResearchRetinoids in leukemia and cellular processes

Cited by 5