Dessimoz, Christophe

Allele-Specific HLA Loss and Immune Escape in Lung Cancer Evolution

McGranahan, N., Rosenthal, R., Hiley, C. T., Rowan, A. J., Watkins, T. B. K., Wilson, G. A., Birkbak, N. J., Veeriah, S., Van Loo, P., Herrero, J., et al. (2017) · Cell

Cancer Immunotherapy and BiomarkersCancer Genomics and Diagnostics

Cited by 1,298

Towards Practical, High-Capacity, Low-Maintenance Information Storage in Synthesized DNA

Goldman, N., Bertone, P., Chen, S., Dessimoz, C., LeProust, E. M., Sipos, B., & Birney, E. (2013) · Nature

DNA and Biological ComputingAdvanced biosensing and bioanalysis techniques

Cited by 1,220

Structural variant calling: the long and the short of it

Mahmoud, M., Gobet, N., Cruz-Dávalos, D. I., Mounier, N., Dessimoz, C., & Sedlazeck, F. J. (2019) · Genome Biology

Genomic variations and chromosomal abnormalitiesGenomics and Phylogenetic Studies

Cited by 725

The CAFA challenge reports improved protein function prediction and new functional annotations for hundreds of genes through experimental screens

Zhou, N., Jiang, Y., Bergquist, T. R., Lee, A. J., Kacsoh, B. Z., Crocker, A. W., Lewis, K. A., Georghiou, G., Nguyen, H. N., Hamid, M. N., et al. (2019) · Genome Biology

Bioinformatics and Genomic NetworksGenomics and Phylogenetic Studies

Cited by 452

Resolving the Ortholog Conjecture: Orthologs Tend to Be Weakly, but Significantly, More Similar in Function than Paralogs

Altenhoff, A. M., Studer, R. A., Robinson-Rechavi, M., & Dessimoz, C. (2012) · PLoS Computational Biology

Genomics and Phylogenetic StudiesBioinformatics and Genomic Networks

Cited by 248

The OMA orthology database in 2018: retrieving evolutionary relationships among all domains of life through richer web and programmatic interfaces

Altenhoff, A. M., Glover, N. M., Train, C.-M., Kaleb, K., Warwick Vesztrocy, A., Dylus, D., de Farias, T. M., Zile, K., Stevenson, C., Long, J., et al. (2018) · Nucleic Acids Research

Genomics and Phylogenetic StudiesBioinformatics and Genomic Networks

Cited by 221

OMA 2011: orthology inference among 1000 complete genomes

Altenhoff, A. M., Schneider, A., Gonnet, G. H., & Dessimoz, C. (2011) · Nucleic Acids Research

Genomics and Phylogenetic StudiesBioinformatics and Genomic Networks

Cited by 215

Standardized benchmarking in the quest for orthologs

Quest for Orthologs consortium, Altenhoff, A. M., Boeckmann, B., Capella-Gutierrez, S., Dalquen, D. A., DeLuca, T., Forslund, K., Huerta-Cepas, J., Linard, B., Pereira, C., et al. (2016) · Nature Methods

Genomics and Phylogenetic StudiesBioinformatics and Genomic Networks

Cited by 214

Quality assessment of gene repertoire annotations with OMArk

Nevers, Y., Warwick Vesztrocy, A., Rossier, V., Train, C.-M., Altenhoff, A., Dessimoz, C., & Glover, N. M. (2025) · Nature Biotechnology

Genomics and Phylogenetic StudiesBioinformatics and Genomic Networks

Cited by 186

Mitigating Anticipated Effects of Systematic Errors Supports Sister-Group Relationship between Xenacoelomorpha and Ambulacraria

Philippe, H., Poustka, A. J., Chiodin, M., Hoff, K. J., Dessimoz, C., Tomiczek, B., Schiffer, P. H., Müller, S., Domman, D., Horn, M., et al. (2019) · Current Biology

Marine Invertebrate Physiology and EcologyInvertebrate Taxonomy and Ecology

Cited by 152

Inferring Orthology and Paralogy

Altenhoff, A. M., Glover, N. M., & Dessimoz, C. (2019) · Methods in Molecular Biology

Genomics and Phylogenetic StudiesBioinformatics and Genomic Networks

Cited by 148

Orthologous Matrix (OMA) algorithm 2.0: more robust to asymmetric evolutionary rates and more scalable hierarchical orthologous group inference

Train, C.-M., Glover, N. M., Gonnet, G. H., Altenhoff, A. M., & Dessimoz, C. (2017) · Bioinformatics

Genomics and Phylogenetic StudiesBioinformatics and Genomic Networks

Cited by 96

Advances and Applications in the Quest for Orthologs

Glover, N., Dessimoz, C., Ebersberger, I., Forslund, S. K., Gabaldón, T., Huerta-Cepas, J., Martin, M.-J., Muffato, M., Patricio, M., Pereira, C., et al. (2019) · Molecular Biology and Evolution

Genomics and Phylogenetic StudiesBioinformatics and Genomic Networks

Cited by 94

Bidirectional Best Hits Miss Many Orthologs in Duplication-Rich Clades such as Plants and Animals

Dalquen, D. A., & Dessimoz, C. (2013) · Genome Biology and Evolution

Genomics and Phylogenetic StudiesChromosomal and Genetic Variations

Cited by 86

Joining forces in the quest for orthologs

Gabaldón, T., Dessimoz, C., Huxley-Jones, J., Vilella, A. J., Sonnhammer, E. L., & Lewis, S. (2009) · Genome Biology

Genomics and Phylogenetic StudiesBioinformatics and Genomic Networks

Cited by 74

Protein length distribution is remarkably uniform across the tree of life

Nevers, Y., Glover, N. M., Dessimoz, C., & Lecompte, O. (2023) · Genome Biology

Genomics and Phylogenetic StudiesChromosomal and Genetic Variations

Cited by 51

Genomic Encryption of Digital Data Stored in Synthetic DNA

Grass, R. N., Heckel, R., Dessimoz, C., & Stark, W. J. (2020) · Angewandte Chemie International Edition

DNA and Biological ComputingCryptography and Data Security

Cited by 34

Orthology inference at scale with FastOMA

Majidian, S., Nevers, Y., Yazdizadeh Kharrazi, A., Warwick Vesztrocy, A., Pascarelli, S., Moi, D., Glover, N., Altenhoff, A. M., & Dessimoz, C. (2025) · Nature Methods

Genomics and Phylogenetic StudiesBioinformatics and Genomic Networks

Cited by 30

Quest for Orthologs in the Era of Biodiversity Genomics

Langschied, F., Bordin, N., Cosentino, S., Fuentes-Palacios, D., Glover, N., Hiller, M., Hu, Y., Huerta-Cepas, J., Coelho, L. P., Iwasaki, W., et al. (2024) · Genome Biology and Evolution

Genomics and Phylogenetic StudiesBioinformatics and Genomic Networks

Cited by 26

Discovery of archaeal Fusexins homologous to eukaryotic HAP2/GCS1 gamete fusion proteins

Moi, D., Nishio, S., Li, X., Valansi, C., Langleib, M., Brukman, N. G., Flyak, K., Dessimoz, C., de Sanctis, D., Tunyasuvunakool, K., et al. (2021) · bioRxiv (Cold Spring Harbor Laboratory)

Bacterial Genetics and BiotechnologyBiochemical and Structural Characterization

Cited by 23

Annotation matters: the effect of structural gene annotation on orthology inference

Prieto-Baños, S., Nevers, Y., Altenhoff, A., Warwick Vesztrocy, A., Dessimoz, C., & Glover, N. M. (2025) · Bioinformatics

Genomics and Phylogenetic StudiesBioinformatics and Genomic Networks

Cited by 19

Control of PHYTOCHROME KINASE SUBSTRATE subcellular localization and biological activity by protein S-acylation

Vazquez, A. L., Petrolati, L. A., Dessimoz, C., Lampugnani, E. R., Glover, N., & Fankhauser, C. (2022) · The Plant Cell

Light effects on plantsPlant Molecular Biology Research

Cited by 12