Kotsinas, Athanassios

Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions

Gorgoulis, V. G., Vassiliou, L.-V. F., Karakaidos, P., Zacharatos, P., Kotsinas, A., Liloglou, T., Venere, M., DiTullio, R. A., Kastrinakis, N. G., Levy, B., et al. (2005) · Nature

DNA Repair MechanismsCancer-related Molecular Pathways

Cited by 2,009

Robust, universal biomarker assay to detect senescent cells in biological specimens

Evangelou, K., Lougiakis, N., Rizou, S. V., Kotsinas, A., Kletsas, D., Muñoz‐Espín, D., Kastrinakis, N. G., Pouli, N., Marakos, P., Townsend, P., et al. (2017) · Aging Cell

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 259

Functional interplay between the DNA-damage-response kinase ATM and ARF tumour suppressor protein in human cancer

Velimezi, G., Liontos, M., Vougas, K., Roumeliotis, T., Bartkova, J., Sideridou, M., Dereli-Oz, A., Kocylowski, M., Pateras, I. S., Evangelou, K., et al. (2013) · Nature Cell Biology

Cancer-related Molecular PathwaysDNA Repair Mechanisms

Cited by 131

Pulmonary infection by SARS-CoV-2 induces senescence accompanied by an inflammatory phenotype in severe COVID-19: possible implications for viral mutagenesis

Evangelou, K., Veroutis, D., Paschalaki, K., Foukas, P. G., Lagopati, N., Dimitriou, M., Papaspyropoulos, A., Konda, B., Hazapis, O., Polyzou, A., et al. (2022) · European Respiratory Journal

COVID-19 Clinical Research StudiesTelomeres, Telomerase, and Senescence

Cited by 98

Mutational signatures reveal the role of RAD52 in p53-independent p21-driven genomic instability

Galanos, P., Pappas, G., Polyzos, A., Kotsinas, A., Svolaki, I., Giakoumakis, N. N., Glytsou, C., Pateras, I. S., Swain, U., Souliotis, V. L., et al. (2018) · Genome Biology

DNA Repair MechanismsCancer Genomics and Diagnostics

Cited by 67

A fluorophore-conjugated reagent enabling rapid detection, isolation and live tracking of senescent cells

Magkouta, S., Veroutis, D., Pousias, A., Papaspyropoulos, A., Pippa, N., Lougiakis, N., Kambas, K., Lagopati, N., Polyzou, A., Georgiou, M., et al. (2023) · Molecular Cell

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 59

The DNA damage checkpoint precedes activation of ARF in response to escalating oncogenic stress during tumorigenesis

Evangelou, K., Bartkova, J., Kotsinas, A., Pateras, I. S., Liontos, M., Velimezi, G., Kosar, M., Liloglou, T., Trougakos, I. P., Dyrskjot, L., et al. (2013) · Cell Death & Differentiation

Cancer-related Molecular PathwaysDNA Repair Mechanisms

Cited by 59

Heregulin, Cysteine Rich-61 and Matrix Metalloproteinase 9 Expression in Human Carotid Atherosclerotic Plaques: Relationship with Clinical Data

Sigala, F., Georgopoulos, S., Papalambros, E., Chasiotis, D., Vourliotakis, G., Niforou, A., Kotsinas, A., Kavantzas, N., Patsouris, E., Gorgoulis, V. G., et al. (2006) · European Journal of Vascular and Endovascular Surgery

Cerebrovascular and Carotid Artery DiseasesAcute Ischemic Stroke Management

Cited by 30

A Novel Quantitative Method for the Detection of Lipofuscin, the Main By-Product of Cellular Senescence, in Fluids

Rizou, S. V., Evangelou, K., Myrianthopoulos, V., Mourouzis, I., Havaki, S., Athanasiou, A., Vasileiou, P. V. S., Margetis, A., Kotsinas, A., Kastrinakis, N. G., et al. (2019) · Methods in Molecular Biology

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 25