Guo, Lei

The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer’s disease

Hur, J.-Y., Frost, G. R., Wu, X., Crump, C., Pan, S. J., Wong, E., Barros, M., Li, T., Nie, P., Zhai, Y., et al. (2020) · Nature

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 382

Molecular subtyping of Alzheimer’s disease using RNA sequencing data reveals novel mechanisms and targets

Neff, R. A., Wang, M., Vatansever, S., Guo, L., Ming, C., Wang, Q., Wang, E., Horgusluoglu-Moloch, E., Song, W.-M., Li, A., et al. (2021) · Science Advances

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 306

Microglia and macrophages promote corralling, wound compaction and recovery after spinal cord injury via Plexin-B2

Zhou, X., Wahane, S., Friedl, M.-S., Kluge, M., Friedel, C. C., Avrampou, K., Zachariou, V., Guo, L., Zhang, B., He, X., et al. (2020) · Nature Neuroscience

Spinal Cord Injury ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 275

Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer’s Disease

Wang, M., Li, A., Sekiya, M., Beckmann, N. D., Quan, X., Schrode, N., Fernando, M. B., Yu, A., Zhu, L., Cao, J., et al. (2021) · Neuron

Alzheimer's disease research and treatmentsBioinformatics and Genomic Networks

Cited by 185

Sex Differences in Alzheimer’s Disease: Insights From the Multiomics Landscape

Guo, L., Zhong, M. B., Zhang, L., Zhang, B., & Cai, D. (2022) · Biological Psychiatry

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 164

Diversified transcriptional responses of myeloid and glial cells in spinal cord injury shaped by HDAC3 activity

Wahane, S., Zhou, X., Zhou, X., Guo, L., Friedl, M.-S., Kluge, M., Ramakrishnan, A., Shen, L., Friedel, C. C., Zhang, B., et al. (2021) · Science Advances

Spinal Cord Injury ResearchNeuroinflammation and Neurodegeneration Mechanisms

Cited by 67

Sex specific molecular networks and key drivers of Alzheimer’s disease

Guo, L., Cao, J., Hou, J., Li, Y., Huang, M., Zhu, L., Zhang, L., Lee, Y., Duarte, M. L., Zhou, X., et al. (2023) · Molecular Neurodegeneration

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 49

deepOrganoid: a brightfield cell viability model for screening matrix-embedded organoids

Powell, R. T., Moussalli, M. J., Guo, L., Bae, G., Singh, P., Stephan, C., Shureiqi, I., & Davies, P. J. (2022) · SLAS Discovery

Cell Image Analysis TechniquesAdvanced Neural Network Applications

Cited by 37

Molecular Networks and Key Regulators of the Dysregulated Neuronal System in Alzheimer’s Disease

Wang, M., Li, A., Sekiya, M., Beckmann, N. D., Quan, X., Schrode, N., Fernando, M. B., Yu, A., Zhu, L., Cao, J., et al. (2019) · bioRxiv (Cold Spring Harbor Laboratory)

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 6