Fawcett, James W.

Chondroitinase ABC promotes functional recovery after spinal cord injury

Bradbury, E. J., Moon, L. D. F., Popat, R. J., King, V. R., Bennett, G. S., Patel, P. N., Fawcett, J. W., & McMahon, S. B. (2002) · Nature

Spinal Cord Injury ResearchNerve injury and regeneration

Cited by 2,357

Reactivation of Ocular Dominance Plasticity in the Adult Visual Cortex

Pizzorusso, T., Medini, P., Berardi, N., Chierzi, S., Fawcett, J. W., & Maffei, L. (2002) · Science

Visual perception and processing mechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 1,679

Regressive Events in Neurogenesis

Cowan, W. M., Fawcett, J. W., O'Leary, D. D. M., & Stanfield, B. B. (1984) · Science

Neurogenesis and neuroplasticity mechanismsAxon Guidance and Neuronal Signaling

Cited by 1,316

The roles of perineuronal nets and the perinodal extracellular matrix in neuronal function

Fawcett, J. W., Oohashi, T., & Pizzorusso, T. (2019) · Nature Reviews Neuroscience

Proteoglycans and glycosaminoglycans researchNeuroscience and Neuropharmacology Research

Cited by 589

The role of chondroitin sulfate proteoglycans in regeneration and plasticity in the central nervous system

Galtrey, C. M., & Fawcett, J. W. (2007) · Brain Research Reviews

Proteoglycans and glycosaminoglycans researchNeurogenesis and neuroplasticity mechanisms

Cited by 575

Animals lacking link protein have attenuated perineuronal nets and persistent plasticity

Carulli, D., Pizzorusso, T., Kwok, J. C. F., Putignano, E., Poli, A., Forostyak, S., Andrews, M. R., Deepa, S. S., Glant, T. T., & Fawcett, J. W. (2010) · Brain

Proteoglycans and glycosaminoglycans researchNeurogenesis and neuroplasticity mechanisms

Cited by 495

Casting a Wide Net: Role of Perineuronal Nets in Neural Plasticity

Sorg, B. A., Berretta, S., Blacktop, J. M., Fawcett, J. W., Kitagawa, H., Kwok, J. C. F., & Miquel, M. (2016) · The Journal of Neuroscience

Proteoglycans and glycosaminoglycans researchNeuroscience and Neuropharmacology Research

Cited by 454

Extracellular matrix and perineuronal nets in CNS repair

Kwok, J. C. F., Dick, G., Wang, D., & Fawcett, J. W. (2011) · Developmental Neurobiology

Proteoglycans and glycosaminoglycans researchNeuroscience and Neuropharmacology Research

Cited by 395

The perineuronal net and the control of CNS plasticity

Wang, D., & Fawcett, J. (2012) · Cell and Tissue Research

Neuroscience and Neuropharmacology ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 373

Composition of Perineuronal Net Extracellular Matrix in Rat Brain

Deepa, S. S., Carulli, D., Galtrey, C., Rhodes, K., Fukuda, J., Mikami, T., Sugahara, K., & Fawcett, J. W. (2006) · Journal of Biological Chemistry

Proteoglycans and glycosaminoglycans researchNeuroscience and Neuropharmacology Research

Cited by 367

Composition of perineuronal nets in the adult rat cerebellum and the cellular origin of their components

Carulli, D., Rhodes, K. E., Brown, D. J., Bonnert, T. P., Pollack, S. J., Oliver, K., Strata, P., & Fawcett, J. W. (2006) · Journal of Comparative Neurology

Proteoglycans and glycosaminoglycans researchNeuroscience and Neuropharmacology Research

Cited by 341

Subcellular Profiling Reveals Distinct and Developmentally Regulated Repertoire of Growth Cone mRNAs

Zivraj, K. H., Tung, Y. C. L., Piper, M., Gumy, L., Fawcett, J. W., Yeo, G. S. H., & Holt, C. E. (2010) · The Journal of Neuroscience

Axon Guidance and Neuronal SignalingRNA Research and Splicing

Cited by 315

Targeting the neural extracellular matrix in neurological disorders

Soleman, S., Filippov, M. A., Dityatev, A., & Fawcett, J. W. (2013) · Neuroscience

Proteoglycans and glycosaminoglycans researchNeurogenesis and neuroplasticity mechanisms

Cited by 244

Depletion of Perineuronal Nets Enhances Recognition Memory and Long-Term Depression in the Perirhinal Cortex

Romberg, C., Yang, S., Melani, R., Andrews, M. R., Horner, A. E., Spillantini, M. G., Bussey, T. J., Fawcett, J. W., Pizzorusso, T., & Saksida, L. M. (2013) · The Journal of Neuroscience

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 231

Matrix metalloproteases and their inhibitors are produced by overlapping populations of activated astrocytes

Muir, E. M., Adcock, K. H., Morgenstern, D. A., Clayton, R., von Stillfried, N., Rhodes, K., Ellis, C., Fawcett, J. W., & Rogers, J. H. (2002) · Molecular Brain Research

Protease and Inhibitor MechanismsTraumatic Brain Injury and Neurovascular Disturbances

Cited by 206

Aggrecan Directs Extracellular Matrix-Mediated Neuronal Plasticity

Rowlands, D., Lensjø, K. K., Dinh, T., Yang, S., Andrews, M. R., Hafting, T., Fyhn, M., Fawcett, J. W., & Dick, G. (2018) · The Journal of Neuroscience

Neurogenesis and neuroplasticity mechanismsNeuroscience and Neuropharmacology Research

Cited by 204

Distribution and synthesis of extracellular matrix proteoglycans, hyaluronan, link proteins and tenascin‐R in the rat spinal cord

Galtrey, C. M., Kwok, J. C. F., Carulli, D., Rhodes, K. E., & Fawcett, J. W. (2008) · European Journal of Neuroscience

Proteoglycans and glycosaminoglycans researchNeurogenesis and neuroplasticity mechanisms

Cited by 203

Microglia-mediated degradation of perineuronal nets promotes pain

Tansley, S., Gu, N., Guzmán, A. U., Cai, W., Wong, C., Lister, K. C., Muñoz-Pino, E., Yousefpour, N., Roome, R. B., Heal, J., et al. (2022) · Science

Pain Mechanisms and TreatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 195

In vitro modeling of perineuronal nets: hyaluronan synthase and link protein are necessary for their formation and integrity

Kwok, J. C. F., Carulli, D., & Fawcett, J. W. (2010) · Journal of Neurochemistry

Proteoglycans and glycosaminoglycans researchNeuroscience and Neuropharmacology Research

Cited by 170

The extracellular matrix and perineuronal nets in memory

Fawcett, J. W., Fyhn, M., Jendelova, P., Kwok, J. C. F., Ruzicka, J., & Sorg, B. A. (2022) · Molecular Psychiatry

Proteoglycans and glycosaminoglycans researchNeuroscience and Neuropharmacology Research

Cited by 169

Semaphorin 3A Binds to the Perineuronal Nets via Chondroitin Sulfate Type E Motifs in Rodent Brains

Dick, G., Tan, C. L., Alves, J. N., Ehlert, E. M. E., Miller, G. M., Hsieh-Wilson, L. C., Sugahara, K., Oosterhof, A., van Kuppevelt, T. H., Verhaagen, J., et al. (2013) · Journal of Biological Chemistry

Proteoglycans and glycosaminoglycans researchAxon Guidance and Neuronal Signaling

Cited by 160

Integrin activation promotes axon growth on inhibitory chondroitin sulfate proteoglycans by enhancing integrin signaling

Tan, C. L., Kwok, J. C. F., Patani, R., ffrench-Constant, C., Chandran, S., & Fawcett, J. W. (2011) · The Journal of Neuroscience

Nerve injury and regenerationProteoglycans and glycosaminoglycans research

Cited by 160

Upregulation of aggrecan, link protein 1, and hyaluronan synthases during formation of perineuronal nets in the rat cerebellum

Carulli, D., Rhodes, K. E., & Fawcett, J. W. (2007) · Journal of Comparative Neurology

Proteoglycans and glycosaminoglycans researchNeurogenesis and neuroplasticity mechanisms

Cited by 158

Perisynaptic Chondroitin Sulfate Proteoglycans Restrict Structural Plasticity in an Integrin-Dependent Manner

Orlando, C., Ster, J., Gerber, U., Fawcett, J. W., & Raineteau, O. (2012) · The Journal of Neuroscience

Proteoglycans and glycosaminoglycans researchNeuroscience and Neuropharmacology Research

Cited by 153