Poulin, Patrick

Prediction of Pharmacokinetics Prior to In Vivo Studies. 1. Mechanism‐Based Prediction of Volume of Distribution

Poulin, P., & Theil, F. (2002) · Journal of Pharmaceutical Sciences

Computational Drug Discovery MethodsPharmacogenetics and Drug Metabolism

Cited by 568

PhRMA CPCDC initiative on predictive models of human pharmacokinetics, part 3: Comparative assessement of prediction methods of human clearance

Ring, B. J., Chien, J. Y., Adkison, K. K., Jones, H. M., Rowland, M., Jones, R. D., Yates, J. W. T., Ku, M. S., Gibson, C. R., He, H., et al. (2011) · Journal of Pharmaceutical Sciences

Pharmaceutical studies and practicesAnimal testing and alternatives

Cited by 206

PHRMA CPCDC initiative on predictive models of human pharmacokinetics, part 5: Prediction of plasma concentration–time profiles in human by using the physiologically‐based pharmacokinetic modeling approach

Poulin, P., Jones, R. D. O., Jones, H. M., Gibson, C. R., Rowland, M., Chien, J. Y., Ring, B. J., Adkison, K. K., Ku, M. S., He, H., et al. (2011) · Journal of Pharmaceutical Sciences

Pharmaceutical studies and practicesPharmacogenetics and Drug Metabolism

Cited by 174

In Vitro–In Vivo Extrapolation of Clearance: Modeling Hepatic Metabolic Clearance of Highly Bound Drugs and Comparative Assessment with Existing Calculation Methods

Poulin, P., Kenny, J. R., Hop, C. E. C. A., & Haddad, S. (2012) · Journal of Pharmaceutical Sciences

Pharmacogenetics and Drug MetabolismDrug Transport and Resistance Mechanisms

Cited by 109

Comparative Assessment of In Vitro–In Vivo Extrapolation Methods used for Predicting Hepatic Metabolic Clearance of Drugs

Poulin, P., Hop, C. E. C. A., Ho, Q., Halladay, J. S., Haddad, S., & Kenny, J. R. (2012) · Journal of Pharmaceutical Sciences

Pharmacogenetics and Drug MetabolismDrug Transport and Resistance Mechanisms

Cited by 64

Toward a new paradigm for the efficient in vitro–in vivo extrapolation of metabolic clearance in humans from hepatocyte data

Poulin, P., & Haddad, S. (2013) · Journal of Pharmaceutical Sciences

Pharmacogenetics and Drug MetabolismDrug Transport and Resistance Mechanisms

Cited by 54