Ivaska, Johanna

Every step of the way: integrins in cancer progression and metastasis

Hamidi, H., & Ivaska, J. (2018) · Nature Reviews Cancer

Cell Adhesion Molecules ResearchCellular Mechanics and Interactions

Cited by 1,493

Integrins as biomechanical sensors of the microenvironment

Kechagia, J. Z., Ivaska, J., & Roca-Cusachs, P. (2019) · Nature Reviews Molecular Cell Biology

Cell Adhesion Molecules ResearchCellular Mechanics and Interactions

Cited by 1,311

CIP2A inhibits PP2A in human malignancies

Junttila, M. R., Puustinen, P., Niemelä, M., Ahola, R., Arnold, H., Böttzauw, T., Ala-aho, R., Nielsen, C., Ivaska, J., Taya, Y., et al. (2007) · Cell

Cancer Mechanisms and TherapyProtein Tyrosine Phosphatases

Cited by 677

Endothelial destabilization by angiopoietin-2 via integrin β1 activation

Hakanpaa, L., Sipila, T., Leppanen, V.-M., Gautam, P., Nurmi, H., Jacquemet, G., Eklund, L., Ivaska, J., Alitalo, K., & Saharinen, P. (2015) · Nature Communications

Angiogenesis and VEGF in CancerCell Adhesion Molecules Research

Cited by 287

CIP2A Is Associated with Human Breast Cancer Aggressivity

Côme, C., Laine, A., Chanrion, M., Edgren, H., Mattila, E., Liu, X., Jonkers, J., Ivaska, J., Isola, J., Darbon, J.-M., et al. (2009) · Clinical Cancer Research

Cancer Mechanisms and TherapyCancer-related Molecular Pathways

Cited by 221

SHARPIN is an endogenous inhibitor of β1-integrin activation

Rantala, J. K., Pouwels, J., Pellinen, T., Veltel, S., Laasola, P., Mattila, E., Potter, C. S., Duffy, T., Sundberg, J. P., Kallioniemi, O., et al. (2011) · Nature Cell Biology

Cell Adhesion Molecules ResearchCellular Mechanics and Interactions

Cited by 201

L-type calcium channels regulate filopodia stability and cancer cell invasion downstream of integrin signalling

Jacquemet, G., Baghirov, H., Georgiadou, M., Sihto, H., Peuhu, E., Cettour-Janet, P., He, T., Perälä, M., Kronqvist, P., Joensuu, H., et al. (2016) · Nature Communications

Cell Adhesion Molecules ResearchCellular Mechanics and Interactions

Cited by 186

Integrin adhesion complexes

Chastney, M. R., Conway, J. R. W., & Ivaska, J. (2021) · Current Biology

Cell Adhesion Molecules ResearchCellular Mechanics and Interactions

Cited by 159

Identification of Protein Interactions Involved in Cellular Signaling

Westermarck, J., Ivaska, J., & Corthals, G. L. (2013) · Molecular & Cellular Proteomics

Advanced Proteomics Techniques and ApplicationsBioinformatics and Genomic Networks

Cited by 143

AMPK negatively regulates tensin-dependent integrin activity

Georgiadou, M., Lilja, J., Jacquemet, G., Guzmán, C., Rafaeva, M., Alibert, C., Yan, Y., Sahgal, P., Lerche, M., Manneville, J.-B., et al. (2017) · Journal of Cell Biology

Cell Adhesion Molecules ResearchCellular Mechanics and Interactions

Cited by 109

Targeting β1-integrin inhibits vascular leakage in endotoxemia

Hakanpaa, L., Kiss, E. A., Jacquemet, G., Miinalainen, I., Lerche, M., Guzmán, C., Mervaala, E., Eklund, L., Ivaska, J., & Saharinen, P. (2018) · Proceedings of the National Academy of Sciences

Cell Adhesion Molecules ResearchBarrier Structure and Function Studies

Cited by 95

PtdIns(3,4,5)P 3 is a regulator of myosin-X localization and filopodia formation

Plantard, L., Arjonen, A., Lock, J. G., Nurani, G., Ivaska, J., & Strömblad, S. (2010) · Journal of Cell Science

Protein Kinase Regulation and GTPase SignalingCellular transport and secretion

Cited by 84

Transcytosis route mediates rapid delivery of intact antibodies to draining lymph nodes

Kähäri, L., Fair-Mäkelä, R., Auvinen, K., Rantakari, P., Jalkanen, S., Ivaska, J., & Salmi, M. (2019) · Journal of Clinical Investigation

Lymphatic System and DiseasesBarrier Structure and Function Studies

Cited by 74

SHARPIN regulates uropod detachment in migrating lymphocytes

Pouwels, J., De Franceschi, N., Rantakari, P., Auvinen, K., Karikoski, M., Mattila, E., Potter, C., Sundberg, J. P., Hogg, N., Gahmberg, C. G., et al. (2013) · Cell Reports

Cell Adhesion Molecules ResearchChemokine receptors and signaling

Cited by 55

Mutually exclusive roles of SHARPIN in integrin inactivation and NF-κB signaling

De Franceschi, N., Peuhu, E., Parsons, M., Rissanen, S., Vattulainen, I., Salmi, M., Ivaska, J., & Pouwels, J. (2015) · PLOS ONE

Cell Adhesion Molecules ResearchNF-κB Signaling Pathways

Cited by 22

TLNRD1 is a CCM complex component and regulates endothelial barrier integrity

Ball, N. J., Ghimire, S., Follain, G., Pajari, A. O., Vaitkevičiūtė, M., Cowell, A. R., Berki, B., Ivaska, J., Paatero, I., Goult, B. T., et al. (2023) · The Journal of Cell Biology

Vascular Malformations Diagnosis and TreatmentBarrier Structure and Function Studies

Cited by 11

TLNRD1 is a CCM complex component and regulates endothelial barrier integrity

Ball, N. J., Ghimire, S., Follain, G., Pajari, A. O., Wurzinger, D., Vaitkevičiūtė, M., Cowell, A. R., Berki, B., Ivaska, J., Paatero, I., et al. (2024) · Journal of Cell Biology

Vascular Malformations Diagnosis and TreatmentBarrier Structure and Function Studies

Cited by 11

Inactive β1-integrin acts as a junctional scaffold for angiopoietin/TIE2/FOXO1 signaling

Sipilä, T., Ponna, S. K., Venkatesha Murthy, A., Pink, A., Enkavi, G., Bohra, S. K., Lewna, K., Ganesh, K., Liu, Q., Korhonen, M., et al. (2026) · Journal of Clinical Investigation

Cell Adhesion Molecules ResearchAngiogenesis and VEGF in Cancer

Cited by 0