Hoeijmakers, Jan H. J.

RAD26, the functional S. cerevisiae homolog of the Cockayne syndrome B gene ERCC6.

van Gool, A. J., Verhage, R., Swagemakers, S. M., van de Putte, P., Brouwer, J., Troelstra, C., Bootsma, D., & Hoeijmakers, J. H. (1994) · The EMBO Journal

DNA Repair MechanismsFungal and yeast genetics research

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Powerful Skin Cancer Protection by a CPD-Photolyase Transgene

Jans, J., Schul, W., Sert, Y.-G., Rijksen, Y., Rebel, H., Eker, A. P. M., Nakajima, S., van Steeg, H., de Gruijl, F. R., Yasui, A., et al. (2005) · Current Biology

DNA Repair MechanismsSkin Protection and Aging

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Delayed and Accelerated Aging Share Common Longevity Assurance Mechanisms

Schumacher, B., van der Pluijm, I., Moorhouse, M. J., Kosteas, T., Robinson, A. R., Suh, Y., Breit, T. M., van Steeg, H., Niedernhofer, L. J., van IJcken, W., et al. (2008) · PLoS Genetics

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

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HHR23B, a Human Rad23 Homolog, Stimulates XPC Protein in Nucleotide Excision Repair In Vitro

Sugasawa, K., Masutani, C., Uchida, A., Maekawa, T., Spek, P. J. V. D., Bootsma, D., Hoeijmakers, J. H. J., & Hanaoka, F. (1996) · Molecular and Cellular Biology

DNA Repair MechanismsNuclear Structure and Function

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Divide and conquer: nucleotide excision repair battles cancer and ageing

Mitchell, J. R., Hoeijmakers, J. H., & Niedernhofer, L. J. (2003) · Current Opinion in Cell Biology

DNA Repair MechanismsGenetics, Aging, and Longevity in Model Organisms

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Global Regulation of Promoter Melting in Naive Lymphocytes

Kouzine, F., Wojtowicz, D., Yamane, A., Resch, W., Kieffer-Kwon, K.-R., Bandle, R., Nelson, S., Nakahashi, H., Awasthi, P., Feigenbaum, L., et al. (2013) · Cell

Genomics and Chromatin DynamicsNuclear Structure and Function

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Xeroderma pigmentosum group A protein loads as a separate factor onto DNA lesions

Rademakers, S., Volker, M., Hoogstraten, D., Nigg, A. L., Moné, M. J., van Zeeland, A. A., Hoeijmakers, J. H. J., Houtsmuller, A. B., & Vermeulen, W. (2003) · Molecular and Cellular Biology

DNA Repair MechanismsNuclear Structure and Function

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Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity

Garinis, G. A., Uittenboogaard, L. M., Stachelscheid, H., Fousteri, M., van Ijcken, W., Breit, T. M., van Steeg, H., Mullenders, L. H. F., van der Horst, G. T. J., Brüning, J. C., et al. (2009) · Nature Cell Biology

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

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Versatile DNA damage detection by the global genome nucleotide excision repair protein XPC

Hoogstraten, D., Bergink, S., Ng, J. M. Y., Verbiest, V. H. M., Luijsterburg, M. S., Geverts, B., Raams, A., Dinant, C., Hoeijmakers, J. H. J., Vermeulen, W., et al. (2008) · Journal of Cell Science

DNA Repair MechanismsNuclear Structure and Function

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Activation of the DNA damage response in vivo in synucleinopathy models of Parkinson’s disease

Milanese, C., Cerri, S., Ulusoy, A., Gornati, S. V., Plat, A., Gabriels, S., Blandini, F., Di Monte, D. A., Hoeijmakers, J. H., & Mastroberardino, P. G. (2018) · Cell Death & Disease

Parkinson's Disease Mechanisms and TreatmentsDNA Repair Mechanisms

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Early postnatal ataxia and abnormal cerebellar development in mice lacking Xeroderma pigmentosum Group A and Cockayne syndrome Group B DNA repair genes

Murai, M., Enokido, Y., Inamura, N., Yoshino, M., Nakatsu, Y., van der Horst, G. T. J., Hoeijmakers, J. H. J., Tanaka, K., & Hatanaka, H. (2001) · Proceedings of the National Academy of Sciences

DNA Repair MechanismsNeurogenesis and neuroplasticity mechanisms

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Identification and Characterization of XPC-Binding Domain of hHR23B

Masutani, C., Araki, M., Sugasawa, K., van der Spek, P. J., Yamada, A., Uchida, A., Maekawa, T., Bootsma, D., Hoeijmakers, J. H. J., & Hanaoka, F. (1997) · Molecular and Cellular Biology

DNA Repair MechanismsNuclear Structure and Function

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Double Mutants of Saccharomyces cerevisiae with Alterations in Global Genome and Transcription-Coupled Repair

Verhage, R. A., Van Gool, A. J., Groot, N. D., Hoeijmakers, J. H. J., Putte, P. V. D., & Brouwer, J. (1996) · Molecular and Cellular Biology

DNA Repair MechanismsFungal and yeast genetics research

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Enhanced Repair of Cyclobutane Pyrimidine Dimers and Improved UV Resistance in Photolyase Transgenic Mice

Schul, W., Jans, J., Rijksen, Y. M. A., Klemann, K. H. M., Eker, A. P. M., de Wit, J., Nikaido, O., Nakajima, S., Yasui, A., Hoeijmakers, J. H. J., et al. (2002) · The EMBO Journal

DNA Repair MechanismsSkin Protection and Aging

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Broad segmental progeroid changes in short-lived Ercc1 −/Δ7 mice

Dollé, M. E. T., Kuiper, R. V., Roodbergen, M., Robinson, J., de Vlugt, S., Wijnhoven, S. W. P., Beems, R. B., de la Fonteyne, L., de With, P., van der Pluijm, I., et al. (2011) · Pathobiology of Aging & Age-related Diseases

Genetics, Aging, and Longevity in Model OrganismsDNA Repair Mechanisms

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Tissue-Specific Suppression of Thyroid Hormone Signaling in Various Mouse Models of Aging

Visser, W. E., Bombardieri, C. R., Zevenbergen, C., Barnhoorn, S., Ottaviani, A., van der Pluijm, I., Brandt, R., Kaptein, E., van Heerebeek, R., van Toor, H., et al. (2016) · PLOS ONE

Thyroid Disorders and TreatmentsGenetics, Aging, and Longevity in Model Organisms

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An Xpd mouse model for the combined xeroderma pigmentosum/Cockayne syndrome exhibiting both cancer predisposition and segmental progeria

Andressoo, J.-O., Mitchell, J. R., de Wit, J., Hoogstraten, D., Volker, M., Toussaint, W., Speksnijder, E., Beems, R. B., van Steeg, H., Jans, J., et al. (2006) · Cancer Cell

DNA Repair MechanismsNuclear Structure and Function

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UV-DDB-dependent regulation of nucleotide excision repair kinetics in living cells

Nishi, R., Alekseev, S., Dinant, C., Hoogstraten, D., Houtsmuller, A. B., Hoeijmakers, J. H. J., Vermeulen, W., Hanaoka, F., & Sugasawa, K. (2009) · DNA Repair

DNA Repair MechanismsNuclear Structure and Function

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Menopause: Genome stability as new paradigm

Laven, J. S. E., Visser, J. A., Uitterlinden, A. G., Vermeij, W. P., & Hoeijmakers, J. H. J. (2016) · Maturitas

Reproductive Biology and FertilityMenopause: Health Impacts and Treatments

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Plant homologue of human excision repair gene ERCC1 points to conservation of DNA repair mechanisms

Xu, H., Swoboda, I., Bhalla, P. L., Sijbers, A. M., Zhao, C., Ong, E., Hoeijmakers, J. H. J., & Singh, M. B. (1998) · The Plant Journal

DNA Repair MechanismsPlant Molecular Biology Research

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Differential Role of Basal Keratinocytes in UV-Induced Immunosuppression and Skin Cancer

Jans, J., Garinis, G. A., Schul, W., van Oudenaren, A., Moorhouse, M., Smid, M., Sert, Y.-G., van der Velde, A., Rijksen, Y., de Gruijl, F. R., et al. (2006) · Molecular and Cellular Biology

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Cellular Concentrations of DDB2 Regulate Dynamic Binding of DDB1 at UV-Induced DNA Damage

Alekseev, S., Luijsterburg, M. S., Pines, A., Geverts, B., Mari, P.-O., Giglia-Mari, G., Lans, H., Houtsmuller, A. B., Mullenders, L. H. F., Hoeijmakers, J. H. J., et al. (2008) · Molecular and Cellular Biology

DNA Repair MechanismsUbiquitin and proteasome pathways

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Unlike dietary restriction, rapamycin fails to extend lifespan and reduce transcription stress in progeroid DNA repair-deficient mice

Birkisdóttir, M. B., Jaarsma, D., Brandt, R. M. C., Barnhoorn, S., van Vliet, N., Imholz, S., van Oostrom, C. T., Nagarajah, B., Portilla Fernández, E., Roks, A. J. M., et al. (2021) · Aging Cell

Genetics, Aging, and Longevity in Model OrganismsAutophagy in Disease and Therapy

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Photorepair of Either CPD or 6-4PP DNA Lesions in Basal Keratinocytes Attenuates Ultraviolet-Induced Skin Effects in Nucleotide Excision Repair Deficient Mice

Kajitani, G. S., Quayle, C., Garcia, C. C. M., Fotoran, W. L., dos Santos, J. F. R., van der Horst, G. T. J., Hoeijmakers, J. H. J., & Menck, C. F. M. (2022) · Frontiers in Immunology

DNA Repair MechanismsSkin Protection and Aging

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