Jackson, Colin J.

The role of protein dynamics in the evolution of new enzyme function

Campbell, E., Kaltenbach, M., Correy, G. J., Carr, P. D., Porebski, B. T., Livingstone, E. K., Afriat-Jurnou, L., Buckle, A. M., Weik, M., Hollfelder, F., et al. (2016) · Nature Chemical Biology

Protein Structure and DynamicsEnzyme Catalysis and Immobilization

Cited by 311

Conformational sampling, catalysis, and evolution of the bacterial phosphotriesterase

Jackson, C. J., Foo, J.-L., Tokuriki, N., Afriat, L., Carr, P. D., Kim, H.-K., Schenk, G., Tawfik, D. S., & Ollis, D. L. (2009) · Proceedings of the National Academy of Sciences

Protein Structure and DynamicsPhysical Organic Chemistry and Reaction Kinetics

Cited by 119

Controlled oxygen delivery to power tissue regeneration

Zoneff, E., Wang, Y., Jackson, C., Smith, O., Duchi, S., Onofrillo, C., Farrugia, B., Moulton, S. E., Williams, R., Parish, C., et al. (2024) · Nature Communications

Tissue Engineering and Regenerative MedicineBone Tissue Engineering Materials

Cited by 89

Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity

Zammit, N. W., Siggs, O. M., Gray, P. E., Horikawa, K., Langley, D. B., Walters, S. N., Daley, S. R., Loetsch, C., Warren, J., Yap, J. Y., et al. (2019) · Nature Immunology

NF-κB Signaling PathwaysImmune Response and Inflammation

Cited by 80

The Redox Cofactor F 420 Protects Mycobacteria from Diverse Antimicrobial Compounds and Mediates a Reductive Detoxification System

Jirapanjawat, T., Ney, B., Taylor, M. C., Warden, A. C., Afroze, S., Russell, R. J., Lee, B. M., Jackson, C. J., Oakeshott, J. G., Pandey, G., et al. (2016) · Applied and Environmental Microbiology

Tuberculosis Research and EpidemiologyMycobacterium research and diagnosis

Cited by 45

Ultrahigh-affinity transport proteins from ubiquitous marine bacteria reveal mechanisms and global patterns of nutrient uptake

Clifton, B. E., Alcolombri, U., Jackson, C. J., & Laurino, P. (2023) · Nature

Microbial Community Ecology and PhysiologyBacterial Genetics and Biotechnology

Cited by 37

The ultra-high affinity transport proteins of ubiquitous marine bacteria

Clifton, B. E., Alcolombri, U., Uechi, G.-I., Jackson, C. J., & Laurino, P. (2024) · Nature

Microbial Community Ecology and PhysiologyBacterial Genetics and Biotechnology

Cited by 37

Cyanobacterial α-carboxysome carbonic anhydrase is allosterically regulated by the Rubisco substrate RuBP

Pulsford, S. B., Outram, M. A., Förster, B., Rhodes, T., Williams, S. J., Badger, M. R., Price, G. D., Jackson, C. J., & Long, B. M. (2024) · Science Advances

Enzyme function and inhibitionPhotosynthetic Processes and Mechanisms

Cited by 25

Cyanobacterial α-carboxysome carbonic anhydrase is allosterically regulated by the Rubisco substrate RuBP

Pulsford, S. B., Outram, M. A., Förster, B., Rhodes, T., Williams, S. J., Badger, M. R., Price, G. D., Jackson, C. J., & Long, B. M. (2023) · Science Advances

Enzyme function and inhibitionPhotosynthetic Processes and Mechanisms

Cited by 25

The role of oligomerization in the optimization of cyclohexadienyl dehydratase conformational dynamics and catalytic activity

East, N. J., Clifton, B. E., Jackson, C. J., & Kaczmarski, J. A. (2022) · Protein Science

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 13

The role of evolutionarily metastable oligomeric states in the optimization of catalytic activity

East, N. J., Clifton, B. E., Jackson, C. J., & Kaczmarski, J. A. (2022) · Protein Science

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 12

Investigating the determinants of performance in machine learning for protein fitness prediction

Sandhu, M., Mater, A. C., Matthews, D. S., Spence, M. A., Lenskiy, A. A., & Jackson, C. (2020) · bioRxiv (Cold Spring Harbor Laboratory)

Protein Structure and DynamicsMachine Learning in Bioinformatics

Cited by 8

Identification and characterization of a bacterial periplasmic solute binding protein that binds L-amino acid amides

Smith, O. B., Frkic, R. L., Rahman, M. G., Jackson, C. J., & Kaczmarski, J. A. (2024) · Biochemistry

Bacterial Genetics and BiotechnologyEnzyme Structure and Function

Cited by 4