Savas, Jeffrey N.

Microglia promote learning-dependent synapse formation through brain-derived neurotrophic factor

Parkhurst, C. N., Yang, G., Ninan, I., Savas, J. N., Yates, J. R., Lafaille, J. J., Hempstead, B. L., Littman, D. R., & Gan, W.-B. (2013) · Cell

Neuroinflammation and Neurodegeneration MechanismsNeuroscience and Neuropharmacology Research

Cited by 2,599

Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson’s disease

Burbulla, L. F., Song, P., Mazzulli, J. R., Zampese, E., Wong, Y. C., Jeon, S., Santos, D. P., Blanz, J., Obermaier, C. D., Strojny, C., et al. (2017) · Science

Parkinson's Disease Mechanisms and TreatmentsAutophagy in Disease and Therapy

Cited by 874

Identification of long-lived proteins reveals exceptional stability of essential cellular structures

Toyama, B. H., Savas, J. N., Park, S. K., Harris, M. S., Ingolia, N. T., Yates, J. R., & Hetzer, M. W. (2013) · Cell

Nuclear Structure and FunctionGenetics, Aging, and Longevity in Model Organisms

Cited by 572

Extremely long-lived nuclear pore proteins in the rat brain

Savas, J. N., Toyama, B. H., Xu, T., Yates, J. R., & Hetzer, M. W. (2012) · Science

Nuclear Structure and FunctionGenetics, Aging, and Longevity in Model Organisms

Cited by 335

Secreted amyloid-β precursor protein functions as a GABA B R1a ligand to modulate synaptic transmission

Rice, H. C., de Malmazet, D., Schreurs, A., Frere, S., Van Molle, I., Volkov, A. N., Creemers, E., Vertkin, I., Nys, J., Ranaivoson, F. M., et al. (2019) · Science

Neuroscience and Neuropharmacology ResearchAlzheimer's disease research and treatments

Cited by 281

Amyloid Accumulation Drives Proteome-wide Alterations in Mouse Models of Alzheimer’s Disease-like Pathology

Savas, J. N., Wang, Y.-Z., DeNardo, L. A., Martinez-Bartolome, S., McClatchy, D. B., Hark, T. J., Shanks, N. F., Cozzolino, K. A., Lavallée-Adam, M., Smukowski, S. N., et al. (2017) · Cell Reports

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 66

The Dichotomous Role of Extracellular Vesicles in the Central Nervous System

Graykowski, D. R., Wang, Y.-Z., Upadhyay, A., & Savas, J. N. (2020) · iScience

Extracellular vesicles in diseaseCellular transport and secretion

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