Harrill, Joshua A.

Bioactivity screening of environmental chemicals using imaging-based high-throughput phenotypic profiling

Nyffeler, J., Willis, C., Lougee, R., Richard, A., Paul-Friedman, K., & Harrill, J. A. (2020) · Toxicology and Applied Pharmacology

Cell Image Analysis TechniquesEnvironmental Toxicology and Ecotoxicology

Cited by 136

Progress towards an OECD reporting framework for transcriptomics and metabolomics in regulatory toxicology

Harrill, J. A., Viant, M. R., Yauk, C. L., Sachana, M., Gant, T. W., Auerbach, S. S., Beger, R. D., Bouhifd, M., O'Brien, J., Burgoon, L., et al. (2021) · Regulatory Toxicology and Pharmacology

Carcinogens and Genotoxicity AssessmentAnimal testing and alternatives

Cited by 105

Considerations for strategic use of high-throughput transcriptomics chemical screening data in regulatory decisions

Harrill, J., Shah, I., Setzer, R. W., Haggard, D., Auerbach, S., Judson, R., & Thomas, R. S. (2019) · Current Opinion in Toxicology

Animal testing and alternativesCarcinogens and Genotoxicity Assessment

Cited by 101

Testing for developmental neurotoxicity using a battery of in vitro assays for key cellular events in neurodevelopment

Harrill, J. A., Freudenrich, T., Wallace, K., Ball, K., Shafer, T. J., & Mundy, W. R. (2018) · Toxicology and Applied Pharmacology

Animal testing and alternativesNeurogenesis and neuroplasticity mechanisms

Cited by 86

Comparative sensitivity of human and rat neural cultures to chemical-induced inhibition of neurite outgrowth

Harrill, J. A., Freudenrich, T. M., Robinette, B. L., & Mundy, W. R. (2011) · Toxicology and Applied Pharmacology

Animal testing and alternativesImmunotoxicology and immune responses

Cited by 85

Knockout of the aryl hydrocarbon receptor results in distinct hepatic and renal phenotypes in rats and mice

Harrill, J. A., Hukkanen, R. R., Lawson, M., Martin, G., Gilger, B., Soldatow, V., LeCluyse, E. L., Budinsky, R. A., Rowlands, J. C., & Thomas, R. S. (2013) · Toxicology and Applied Pharmacology

Toxic Organic Pollutants ImpactPharmacogenetics and Drug Metabolism

Cited by 83

Application of Cell Painting for chemical hazard evaluation in support of screening-level chemical assessments

Nyffeler, J., Willis, C., Harris, F. R., Foster, M. J., Chambers, B., Culbreth, M., Brockway, R. E., Davidson-Fritz, S., Dawson, D., Shah, I., et al. (2023) · Toxicology and Applied Pharmacology

Cell Image Analysis TechniquesEnvironmental Toxicology and Ecotoxicology

Cited by 67

An expert-driven literature review of “negative” chemicals for developmental neurotoxicity (DNT) in vitro assay evaluation

Martin, M. M., Baker, N. C., Boyes, W. K., Carstens, K. E., Culbreth, M. E., Gilbert, M. E., Harrill, J. A., Nyffeler, J., Padilla, S., Friedman, K. P., et al. (2022) · Neurotoxicology and Teratology

Animal testing and alternativesImmunotoxicology and immune responses

Cited by 29

Navigating Transcriptomic Connectivity Mapping Workflows to Link Chemicals with Bioactivities

Shah, I., Bundy, J., Chambers, B., Everett, L. J., Haggard, D., Harrill, J., Judson, R. S., Nyffeler, J., & Patlewicz, G. (2022) · Chemical Research in Toxicology

Computational Drug Discovery MethodsBioinformatics and Genomic Networks

Cited by 19