Distrutti, Eleonora

The bile acid receptor FXR is a modulator of intestinal innate immunity

Vavassori, P., Mencarelli, A., Renga, B., Distrutti, E., & Fiorucci, S. (2009) · The Journal of Immunology

Inflammatory Bowel DiseaseDrug Transport and Resistance Mechanisms

Cited by 655

Bile Acid-Activated Receptors, Intestinal Microbiota, and the Treatment of Metabolic Disorders

Fiorucci, S., & Distrutti, E. (2015) · Trends in Molecular Medicine

Gut microbiota and healthDrug Transport and Resistance Mechanisms

Cited by 539

The bile acid receptor GPBAR-1 (TGR5) modulates integrity of intestinal barrier and immune response to experimental colitis

Cipriani, S., Mencarelli, A., Chini, M. G., Distrutti, E., Renga, B., Bifulco, G., Baldelli, F., Donini, A., & Fiorucci, S. (2011) · PLoS ONE

Inflammatory Bowel DiseaseDrug Transport and Resistance Mechanisms

Cited by 382

Gut microbiota role in irritable bowel syndrome: New therapeutic strategies

Distrutti, E., Monaldi, L., Ricci, P., & Fiorucci, S. (2016) · World Journal of Gastroenterology

Gastrointestinal motility and disordersGut microbiota and health

Cited by 320

Modulation of Intestinal Microbiota by the Probiotic VSL#3 Resets Brain Gene Expression and Ameliorates the Age-Related Deficit in LTP

Distrutti, E., O’Reilly, J.-A., McDonald, C., Cipriani, S., Renga, B., Lynch, M. A., & Fiorucci, S. (2014) · PLoS ONE

Gut microbiota and healthProbiotics and Fermented Foods

Cited by 237

The bile acid sensor farnesoid X receptor is a modulator of liver immunity in a rodent model of acute hepatitis

Mencarelli, A., Renga, B., Migliorati, M., Cipriani, S., Distrutti, E., Santucci, L., & Fiorucci, S. (2009) · The Journal of Immunology

Liver Diseases and ImmunityLiver physiology and pathology

Cited by 177

5-Amino-2-hydroxybenzoic Acid 4-(5-Thioxo-5 H-[1,2]dithiol-3yl)-phenyl Ester (ATB-429), a Hydrogen Sulfide-Releasing Derivative of Mesalamine, Exerts Antinociceptive Effects in a Model of Postinflammatory Hypersensitivity

Distrutti, E., Sediari, L., Mencarelli, A., Renga, B., Orlandi, S., Russo, G., Caliendo, G., Santagada, V., Cirino, G., Wallace, J. L., et al. (2006) · The Journal of Pharmacology and Experimental Therapeutics

Gastrointestinal motility and disordersPain Mechanisms and Treatments

Cited by 144

Probiotics VSL#3 Protect against Development of Visceral Pain in Murine Model of Irritable Bowel Syndrome

Distrutti, E., Cipriani, S., Mencarelli, A., Renga, B., & Fiorucci, S. (2013) · PLoS ONE

Gastrointestinal motility and disordersProbiotics and Fermented Foods

Cited by 107

Bile acids activated receptors in inflammatory bowel disease

Biagioli, M., Marchianò, S., Carino, A., Di Giorgio, C., Santucci, L., Distrutti, E., & Fiorucci, S. (2021) · Cells

Gut microbiota and healthDrug Transport and Resistance Mechanisms

Cited by 103

SHP-dependent and -independent induction of peroxisome proliferator-activated receptor-γ by the bile acid sensor farnesoid X receptor counter-regulates the pro-inflammatory phenotype of liver myofibroblasts

Renga, B., Mencarelli, A., Migliorati, M., Cipriani, S., D’Amore, C., Distrutti, E., & Fiorucci, S. (2011) · Inflammation Research

Liver physiology and pathologyPeroxisome Proliferator-Activated Receptors

Cited by 53

Combinatorial targeting of G‐protein‐coupled bile acid receptor 1 and cysteinyl leukotriene receptor 1 reveals a mechanistic role for bile acids and leukotrienes in drug‐induced liver injury

Biagioli, M., Marchianò, S., di Giorgio, C., Roselli, R., Bordoni, M., Bellini, R., Fiorillo, B., Sepe, V., Catalanotti, B., Cassiano, C., et al. (2023) · Hepatology

Drug-Induced Hepatotoxicity and ProtectionLiver physiology and pathology

Cited by 28

Decoding the role of the nuclear receptor SHP in regulating hepatic stellate cells and liver fibrogenesis

Cipriani, S., Carino, A., Masullo, D., Zampella, A., Distrutti, E., & Fiorucci, S. (2017) · Scientific Reports

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 16