Scolnick, Edward M.

De novo mutations in schizophrenia implicate synaptic networks

Fromer, M., Pocklington, A. J., Kavanagh, D. H., Williams, H. J., Dwyer, S., Gormley, P., Georgieva, L., Rees, E., Palta, P., Ruderfer, D. M., et al. (2014) · Nature

Schizophrenia research and treatmentGenetics and Neurodevelopmental Disorders

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Genome-wide association analysis identifies 13 new risk loci for schizophrenia

Multicenter Genetic Studies of Schizophrenia Consortium, Ripke, S., Psychosis Endophenotypes International Consortium, Wellcome Trust Case Control Consortium 2, O'Dushlaine, C., Chambert, K., Moran, J. L., Kähler, A. K., Akterin, S., Bergen, S. E., et al. (2013) · Nature Genetics

Schizophrenia research and treatmentGenetic Associations and Epidemiology

Cited by 1,496

Mechanism of activation of a human oncogene

Tabin, C. J., Bradley, S. M., Bargmann, C. I., Weinberg, R. A., Papageorge, A. G., Scolnick, E. M., Dhar, R., Lowy, D. R., & Chang, E. H. (1982) · Nature

Cancer-related Molecular PathwaysBladder and Urothelial Cancer Treatments

Cited by 1,393

A polygenic burden of rare disruptive mutations in schizophrenia

Purcell, S. M., Moran, J. L., Fromer, M., Ruderfer, D., Solovieff, N., Roussos, P., O’Dushlaine, C., Chambert, K., Bergen, S. E., Kähler, A., et al. (2014) · Nature

Schizophrenia research and treatmentGenetic Associations and Epidemiology

Cited by 1,385

Active human immunodeficiency virus protease is required for viral infectivity

Kohl, N. E., Emini, E. A., Schleif, W. A., Davis, L. J., Heimbach, J. C., Dixon, R. A., Scolnick, E. M., & Sigal, I. S. (1988) · Proceedings of the National Academy of Sciences

HIV Research and TreatmentHIV/AIDS drug development and treatment

Cited by 1,307

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

Vilhjálmsson, B. J., Yang, J., Finucane, H. K., Gusev, A., Lindström, S., Ripke, S., Genovese, G., Loh, P.-R., Bhatia, G., Do, R., et al. (2015) · The American Journal of Human Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 1,303

Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder

Wellcome Trust Case Control Consortium, Ferreira, M. A. R., O'Donovan, M. C., Meng, Y. A., Jones, I. R., Ruderfer, D. M., Jones, L., Fan, J., Kirov, G., Perlis, R. H., et al. (2008) · Nature Genetics

Bipolar Disorder and TreatmentGenetic Associations and Epidemiology

Cited by 1,237

Contribution of copy number variants to schizophrenia from a genome-wide study of 41,321 subjects

Marshall, C. R., Howrigan, D. P., Merico, D., Thiruvahindrapuram, B., Wu, W., Greer, D. S., Antaki, D., Shetty, A., Holmans, P. A., Pinto, D., et al. (2017) · Nature Genetics

Genomic variations and chromosomal abnormalitiesSchizophrenia research and treatment

Cited by 1,058

Rare coding variants in ten genes confer substantial risk for schizophrenia

Singh, T., Poterba, T., Curtis, D., Akil, H., Al Eissa, M., Barchas, J. D., Bass, N., Bigdeli, T. B., Breen, G., Bromet, E. J., et al. (2022) · Nature

Schizophrenia research and treatmentGenetic Associations and Epidemiology

Cited by 983

Validating therapeutic targets through human genetics

Plenge, R. M., Scolnick, E. M., & Altshuler, D. (2013) · Nature Reviews Drug Discovery

Genetic Associations and EpidemiologyComputational Drug Discovery Methods

Cited by 712

Recurrence risks for schizophrenia in a Swedish National Cohort

LICHTENSTEIN, P., BJÖRK, C., HULTMAN, C. M., SCOLNICK, E., SKLAR, P., & SULLIVAN, P. F. (2006) · Psychological Medicine

Schizophrenia research and treatmentGenetic Associations and Epidemiology

Cited by 197

In Vitro Synthesis of DNA Complementary to Purified Rabbit Globin mRNA

Ross, J., Aviv, H., Scolnick, E., & Leder, P. (1972) · Proceedings of the National Academy of Sciences

RNA and protein synthesis mechanismsMolecular Biology Techniques and Applications

Cited by 192

Kinetically selective inhibitors of histone deacetylase 2 (HDAC2) as cognition enhancers

Wagner, F. F., Zhang, Y.-L., Fass, D. M., Joseph, N., Gale, J. P., Weïwer, M., McCarren, P., Fisher, S. L., Kaya, T., Zhao, W.-N., et al. (2015) · Chemical Science

Histone Deacetylase Inhibitors ResearchCholinesterase and Neurodegenerative Diseases

Cited by 104

An inherited duplication at the gene p21 Protein-Activated Kinase 7 (PAK7) is a risk factor for psychosis

Morris, D. W., Pearson, R. D., Cormican, P., Kenny, E. M., O'Dushlaine, C. T., Perreault, L.-P. L., Giannoulatou, E., Tropea, D., Maher, B. S., Wormley, B., et al. (2014) · Human Molecular Genetics

Schizophrenia research and treatmentGenomic variations and chromosomal abnormalities

Cited by 42

Advancing drug discovery for schizophrenia

Marder, S. R., Roth, B., Sullivan, P. F., Scolnick, E. M., Nestler, E. J., Geyer, M. A., Welnberger, D. R., Karayiorgou, M., Guidotti, A., Gingrich, J., et al. (2011) · Annals of the New York Academy of Sciences

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

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