Dunbrack, Roland L.

The Rosetta All-Atom Energy Function for Macromolecular Modeling and Design

Alford, R. F., Leaver-Fay, A., Jeliazkov, J. R., O’Meara, M. J., DiMaio, F. P., Park, H., Shapovalov, M. V., Renfrew, P. D., Mulligan, V. K., Kappel, K., et al. (2017) · Journal of Chemical Theory and Computation

Protein Structure and DynamicsRNA and protein synthesis mechanisms

Cited by 1,532

A smoothed backbone-dependent rotamer library for proteins derived from adaptive kernel density estimates and regressions

Shapovalov, M. V., & Dunbrack, R. L. (2011) · Structure

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 1,000

Macromolecular modeling and design in Rosetta: recent methods and frameworks

Leman, J. K., Weitzner, B. D., Lewis, S. M., Adolf-Bryfogle, J., Alam, N., Alford, R. F., Aprahamian, M., Baker, D., Barlow, K. A., Barth, P., et al. (2020) · Nature Methods

Protein Structure and DynamicsComputational Drug Discovery Methods

Cited by 888

Formation of MacroH2A-Containing Senescence-Associated Heterochromatin Foci and Senescence Driven by ASF1a and HIRA

Zhang, R., Poustovoitov, M. V., Ye, X., Santos, H. A., Chen, W., Daganzo, S. M., Erzberger, J. P., Serebriiskii, I. G., Canutescu, A. A., Dunbrack, R. L., et al. (2005) · Developmental Cell

Telomeres, Telomerase, and SenescenceGenomics and Chromatin Dynamics

Cited by 699

A new clustering of antibody CDR loop conformations

North, B., Lehmann, A., & Dunbrack, R. L. (2011) · Journal of Molecular Biology

Protein Structure and DynamicsMonoclonal and Polyclonal Antibodies Research

Cited by 380

Defining a new nomenclature for the structures of active and inactive kinases

Modi, V., & Dunbrack, R. L. (2019) · Proceedings of the National Academy of Sciences

Protein Structure and DynamicsProtein Kinase Regulation and GTPase Signaling

Cited by 367

RosettaAntibodyDesign (RAbD): a general framework for computational antibody design

Adolf-Bryfogle, J., Kalyuzhniy, O., Kubitz, M., Weitzner, B. D., Hu, X., Adachi, Y., Schief, W. R., & Dunbrack, R. L. (2018) · PLoS Computational Biology

Protein Structure and DynamicsMonoclonal and Polyclonal Antibodies Research

Cited by 227

Kincore: a web resource for structural classification of protein kinases and their inhibitors

Modi, V., & Dunbrack, R. L. (2022) · Nucleic Acids Research

Protein Structure and DynamicsProtein Kinase Regulation and GTPase Signaling

Cited by 133

PDBe-KB: collaboratively defining the biological context of structural data

PDBe-KB consortium, Varadi, M., Anyango, S., Armstrong, D., Berrisford, J., Choudhary, P., Deshpande, M., Nadzirin, N., Nair, S. S., Pravda, L., et al. (2022) · Nucleic Acids Research

Enzyme Structure and FunctionProtein Structure and Dynamics

Cited by 82

Delineating the RAS Conformational Landscape

Parker, M. I., Meyer, J. E., Golemis, E. A., & Dunbrack (2022) · Cancer Research

Protein Kinase Regulation and GTPase SignalingProtein Structure and Dynamics

Cited by 30

Exploring Co-occurring POLE Exonuclease and Non-exonuclease Domain Mutations and Their Impact on Tumor Mutagenicity

Shah, S. M., Demidova, E. V., Ringenbach, S., Faezov, B., Andrake, M., Gandhi, A., Mur, P., Viana-Errasti, J., Xiu, J., Swensen, J., et al. (2024) · Cancer Research Communications

Cancer Genomics and DiagnosticsGenetic factors in colorectal cancer

Cited by 16

Targeting Dysregulated Ion Channels in Liver Tumors with Venom Peptides

Achimba, F., Faezov, B., Cohen, B., Dunbrack, R., & Holford, M. (2024) · Molecular Cancer Therapeutics

Healthcare and Venom ResearchVenomous Animal Envenomation and Studies

Cited by 6

Data from Delineating the RAS Conformational Landscape

Parker, M. I., Meyer, J. E., Golemis, E. A., & Dunbrack (2023)

Protein Kinase Regulation and GTPase SignalingProtein Structure and Dynamics

Cited by 1

Data from Delineating the RAS Conformational Landscape

Parker, M. I., Meyer, J. E., Golemis, E. A., & Dunbrack (2023)

Protein Kinase Regulation and GTPase SignalingProtein Structure and Dynamics

Cited by 0