Ward, Simon E.

Therapeutic opportunities within the DNA damage response

Pearl, L. H., Schierz, A. C., Ward, S. E., Al-Lazikani, B., & Pearl, F. M. G. (2015) · Nature Reviews Cancer

DNA Repair MechanismsCancer-related Molecular Pathways

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Epigenetic changes in histone acetylation underpin resistance to the topoisomerase I inhibitor irinotecan

Meisenberg, C., Ashour, M. E., El-Shafie, L., Liao, C., Hodgson, A., Pilborough, A., Khurram, S. A., Downs, J. A., Ward, S. E., & El-Khamisy, S. F. (2016) · Nucleic Acids Research

Cancer therapeutics and mechanismsHistone Deacetylase Inhibitors Research

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Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein

Chen, X., Ali, Y. I., Fisher, C. E., Arribas-Bosacoma, R., Rajasekaran, M. B., Williams, G., Walker, S., Booth, J. R., Hudson, J. J., Roe, S. M., et al. (2021) · eLife

DNA Repair MechanismsEnzyme Structure and Function

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