Bronson, Roderick T.

Suppression of lung adenocarcinoma progression by Nkx2-1

Winslow, M. M., Dayton, T. L., Verhaak, R. G. W., Kim-Kiselak, C., Snyder, E. L., Feldser, D. M., Hubbard, D. D., DuPage, M. J., Whittaker, C. A., Hoersch, S., et al. (2011) · Nature

Cancer Cells and MetastasisMechanisms of cancer metastasis

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The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies

Ji, H., Li, D., Chen, L., Shimamura, T., Kobayashi, S., McNamara, K., Mahmood, U., Mitchell, A., Sun, Y., Al-Hashem, R., et al. (2006) · Cancer Cell

Lung Cancer Treatments and MutationsHER2/EGFR in Cancer Research

Cited by 462

Engineered bacteria can function in the mammalian gut long-term as live diagnostics of inflammation

Riglar, D. T., Giessen, T. W., Baym, M., Kerns, S. J., Niederhuber, M. J., Bronson, R. T., Kotula, J. W., Gerber, G. K., Way, J. C., & Silver, P. A. (2017) · Nature Biotechnology

Bacterial Cancer TherapyGene Regulatory Network Analysis

Cited by 426

An siRNA-based microbicide protects mice from lethal herpes simplex virus 2 infection

Palliser, D., Chowdhury, D., Wang, Q.-Y., Lee, S. J., Bronson, R. T., Knipe, D. M., & Lieberman, J. (2006) · Nature

RNA Interference and Gene DeliveryHerpesvirus Infections and Treatments

Cited by 410

Intrinsic Requirement for Zinc Finger Transcription Factor Gfi-1 in Neutrophil Differentiation

Hock, H., Hamblen, M. J., Rooke, H. M., Traver, D., Bronson, R. T., Cameron, S., & Orkin, S. H. (2003) · Immunity

Blood disorders and treatmentsNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 384

Long-term Safety and Efficacy Following Systemic Administration of a Self-complementary AAV Vector Encoding Human FIX Pseudotyped With Serotype 5 and 8 Capsid Proteins

Nathwani, A. C., Rosales, C., McIntosh, J., Rastegarlari, G., Nathwani, D., Raj, D., Nawathe, S., Waddington, S. N., Bronson, R., Jackson, S., et al. (2011) · Molecular Therapy

Virus-based gene therapy researchHemophilia Treatment and Research

Cited by 345

Classification of Proliferative Pulmonary Lesions of the Mouse

Nikitin, A. Y., Alcaraz, A., Anver, M. R., Bronson, R. T., Cardiff, R. D., Dixon, D., Fraire, A. E., Gabrielson, E. W., Gunning, W. T., Haines, D. C., et al. (2004) · Cancer Research

Veterinary Oncology ResearchLung Cancer Research Studies

Cited by 334

Neuronal loss and brain atrophy in mice lacking cathepsins B and L

Felbor, U., Kessler, B., Mothes, W., Goebel, H. H., Ploegh, H. L., Bronson, R. T., & Olsen, B. R. (2002) · Proceedings of the National Academy of Sciences

Protease and Inhibitor MechanismsCalpain Protease Function and Regulation

Cited by 334

Differential induction of apoptosis in HER2 and EGFR addicted cancers following PI3K inhibition

Faber, A. C., Li, D., Song, Y., Liang, M.-C., Yeap, B. Y., Bronson, R. T., Lifshits, E., Chen, Z., Maira, S.-M., García-Echeverría, C., et al. (2009) · Proceedings of the National Academy of Sciences

PI3K/AKT/mTOR signaling in cancerLung Cancer Treatments and Mutations

Cited by 319

Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure

Minamishima, Y. A., Moslehi, J., Bardeesy, N., Cullen, D., Bronson, R. T., & Kaelin, W. G. (2008) · Blood

Erythropoietin and Anemia TreatmentCancer, Hypoxia, and Metabolism

Cited by 294

mTORC1 promotes survival through translational control of Mcl-1

Mills, J. R., Hippo, Y., Robert, F., Chen, S. M. H., Malina, A., Lin, C.-J., Trojahn, U., Wendel, H.-G., Charest, A., Bronson, R. T., et al. (2008) · Proceedings of the National Academy of Sciences

PI3K/AKT/mTOR signaling in cancerCell death mechanisms and regulation

Cited by 285

The CD155/TIGIT axis promotes and maintains immune evasion in neoantigen-expressing pancreatic cancer

Freed-Pastor, W. A., Lambert, L. J., Ely, Z. A., Pattada, N. B., Bhutkar, A., Eng, G., Mercer, K. L., Garcia, A. P., Lin, L., Rideout, W. M., et al. (2021) · Cancer Cell

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 273

Development of mice expressing a single D-type cyclin

Ciemerych, M. A., Kenney, A. M., Sicinska, E., Kalaszczynska, I., Bronson, R. T., Rowitch, D. H., Gardner, H., & Sicinski, P. (2002) · Genes & Development

Cancer-related Molecular PathwaysDevelopmental Biology and Gene Regulation

Cited by 267

Elucidating Distinct Roles for NF1 in Melanomagenesis

Maertens, O., Johnson, B., Hollstein, P., Frederick, D. T., Cooper, Z. A., Messiaen, L., Bronson, R. T., McMahon, M., Granter, S., Flaherty, K., et al. (2013) · Cancer Discovery

Melanoma and MAPK PathwaysNeurofibromatosis and Schwannoma Cases

Cited by 258

Exploiting cancer cell vulnerabilities to develop a combination therapy for ras-driven tumors

De Raedt, T., Walton, Z., Yecies, J. L., Li, D., Chen, Y., Malone, C. F., Maertens, O., Jeong, S. M., Bronson, R. T., Lebleu, V., et al. (2011) · Cancer Cell

Protein Kinase Regulation and GTPase SignalingEndoplasmic Reticulum Stress and Disease

Cited by 258

Oncogenic KRAS supports pancreatic cancer through regulation of nucleotide synthesis

Santana-Codina, N., Roeth, A. A., Zhang, Y., Yang, A., Mashadova, O., Asara, J. M., Wang, X., Bronson, R. T., Lyssiotis, C. A., Ying, H., et al. (2018) · Nature Communications

Pancreatic and Hepatic Oncology ResearchCancer, Hypoxia, and Metabolism

Cited by 252

Impaired thymic tolerance to α-myosin directs autoimmunity to the heart in mice and humans

Lv, H., Havari, E., Pinto, S., Gottumukkala, R. V. S. R. K., Cornivelli, L., Raddassi, K., Matsui, T., Rosenzweig, A., Bronson, R. T., Smith, R., et al. (2011) · Journal of Clinical Investigation

Viral Infections and Immunology ResearchT-cell and B-cell Immunology

Cited by 228

Tumor formation and inactivation of RIZ1, an Rb-binding member of a nuclear protein-methyltransferase superfamily

Steele-Perkins, G., Fang, W., Yang, X.-H., Van Gele, M., Carling, T., Gu, J., Buyse, I. M., Fletcher, J. A., Liu, J., Bronson, R., et al. (2001) · Genes & Development

Epigenetics and DNA MethylationCancer-related gene regulation

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Mutational landscape of EGFR- , MYC- , and Kras- driven genetically engineered mouse models of lung adenocarcinoma

McFadden, D. G., Politi, K., Bhutkar, A., Chen, F. K., Song, X., Pirun, M., Santiago, P. M., Kim-Kiselak, C., Platt, J. T., Lee, E., et al. (2016) · Proceedings of the National Academy of Sciences

Cancer Genomics and DiagnosticsLung Cancer Treatments and Mutations

Cited by 194

Mutations in the WRN Gene in Mice Accelerate Mortality in a p53-Null Background

Lombard, D. B., Beard, C., Johnson, B., Marciniak, R. A., Dausman, J., Bronson, R., Buhlmann, J. E., Lipman, R., Curry, R., Sharpe, A., et al. (2000) · Molecular and Cellular Biology

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

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WAVE2 deficiency reveals distinct roles in embryogenesis and Rac‐mediated actin‐based motility

Yan, C., Martinez‐Quiles, N., Eden, S., Shibata, T., Takeshima, F., Shinkura, R., Fujiwara, Y., Bronson, R., Snapper, S. B., Kirschner, M. W., et al. (2003) · The EMBO Journal

Protein Kinase Regulation and GTPase SignalingCellular Mechanics and Interactions

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A Milieu Molecule for TGF-β Required for Microglia Function in the Nervous System

Qin, Y., Garrison, B. S., Ma, W., Wang, R., Jiang, A., Li, J., Mistry, M., Bronson, R. T., Santoro, D., Franco, C., et al. (2018) · Cell

TGF-β signaling in diseasesNeuroinflammation and Neurodegeneration Mechanisms

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A feedback loop involving the Phd3 prolyl hydroxylase tunes the mammalian hypoxic response in vivo

Minamishima, Y. A., Moslehi, J., Padera, R. F., Bronson, R. T., Liao, R., & Kaelin, W. G. (2009) · Molecular and Cellular Biology

Cancer, Hypoxia, and MetabolismErythropoietin and Anemia Treatment

Cited by 161

Persistent activation of microglia is associated with neuronal dysfunction of callosal projecting pathways and multiple sclerosis-like lesions in relapsing–remitting experimental autoimmune encephalomyelitis

Rasmussen, S., Wang, Y., Kivisäkk, P., Bronson, R. T., Meyer, M., Imitola, J., & Khoury, S. J. (2007) · Brain

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

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