Luker, Gary D.

Opportunities and challenges for use of tumor spheroids as models to test drug delivery and efficacy

Mehta, G., Hsiao, A. Y., Ingram, M., Luker, G. D., & Takayama, S. (2012) · Journal of Controlled Release

3D Printing in Biomedical ResearchCancer Cells and Metastasis

Cited by 1,172

Microfluidic Endothelium for Studying the Intravascular Adhesion of Metastatic Breast Cancer Cells

Song, J. W., Cavnar, S. P., Walker, A. C., Luker, K. E., Gupta, M., Tung, Y.-C., Luker, G. D., & Takayama, S. (2009) · PLoS ONE

Chemokine receptors and signalingCancer Cells and Metastasis

Cited by 317

CXCR7 influences leukocyte entry into the CNS parenchyma by controlling abluminal CXCL12 abundance during autoimmunity

Cruz-Orengo, L., Holman, D. W., Dorsey, D., Zhou, L., Zhang, P., Wright, M., McCandless, E. E., Patel, J. R., Luker, G. D., Littman, D. R., et al. (2011) · Journal of Experimental Medicine

Chemokine receptors and signalingBarrier Structure and Function Studies

Cited by 231

Expansion of CTCs from early stage lung cancer patients using a microfluidic co-culture model

Zhang, Z., Shiratsuchi, H., Lin, J., Chen, G., Reddy, R. M., Azizi, E., Fouladdel, S., Chang, A. C., Lin, L., Jiang, H., et al. (2014) · Oncotarget

Cancer Cells and MetastasisMicrofluidic and Bio-sensing Technologies

Cited by 207

Optimization of Aqueous Biphasic Tumor Spheroid Microtechnology for Anti-cancer Drug Testing in 3D Culture

Lemmo, S., Atefi, E., Luker, G. D., & Tavana, H. (2014) · Cellular and Molecular Bioengineering

3D Printing in Biomedical ResearchCancer Cells and Metastasis

Cited by 71

Short-term cellular memory tunes the signaling responses of the chemokine receptor CXCR4

Spinosa, P. C., Humphries, B. A., Lewin Mejia, D., Buschhaus, J. M., Linderman, J. J., Luker, G. D., & Luker, K. E. (2019) · Science Signaling

Chemokine receptors and signalingPI3K/AKT/mTOR signaling in cancer

Cited by 31

Pre-existing Cell States Control Heterogeneity of Both EGFR and CXCR4 Signaling

Spinosa, P. C., Kinnunen, P. C., Humphries, B. A., Luker, G. D., Luker, K. E., & Linderman, J. J. (2021) · Cellular and Molecular Bioengineering

Gene Regulatory Network AnalysisProtein Kinase Regulation and GTPase Signaling

Cited by 10

Oscillatory ERK Signaling and Morphology Determine Heterogeneity of Breast Cancer Cell Chemotaxis via MEK-ERK and p38-MAPK Signaling Pathways

Ho, K. K. Y., Srivastava, S., Kinnunen, P. C., Garikipati, K., Luker, G. D., & Luker, K. E. (2023) · Bioengineering

Gene Regulatory Network AnalysisProtein Kinase Regulation and GTPase Signaling

Cited by 8

Inference of weak-form partial differential equations describing migration and proliferation mechanisms in wound healing experiments on cancer cells

Srivastava, S., Kinnunen, P. C., Wang, Z., Ho, K. K. Y., Humphries, B. A., Chen, S., Linderman, J. J., Luker, G. D., Luker, K. E., & Garikipati, K. (2025) · PLOS Computational Biology

Mathematical Biology Tumor GrowthCellular Mechanics and Interactions

Cited by 5

Computational modeling implicates protein scaffolding in p38 regulation of Akt

Kinnunen, P. C., Luker, G. D., Luker, K. E., & Linderman, J. J. (2022) · Journal of Theoretical Biology

Protein Kinase Regulation and GTPase SignalingGene Regulatory Network Analysis

Cited by 4