Dyson, Nicholas J.

The human papilloma virus-16 E7-oncoprotein is able to bind to the retinoblastoma gene product

Dyson, N., Howley, P. M., Münger, K., & Harlow, E. (1989) · Science

Cervical Cancer and HPV ResearchCancer-related Molecular Pathways

Cited by 3,017

The regulation of E2F by pRB-family proteins.

Dyson, N. (1998) · Genes & Development

Cancer-related Molecular PathwaysGenomics and Chromatin Dynamics

Cited by 2,317

Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism

Perera, R. M., Stoykova, S., Nicolay, B. N., Ross, K. N., Fitamant, J., Boukhali, M., Lengrand, J., Deshpande, V., Selig, M. K., Ferrone, C. R., et al. (2015) · Nature

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 799

The E2F transcriptional network: old acquaintances with new faces

Dimova, D. K., & Dyson, N. J. (2005) · Oncogene

Cancer-related Molecular PathwaysGenomics and Chromatin Dynamics

Cited by 715

pRB and p107/p130 are required for the regulated expression of different sets of E2F responsive genes

Hurford, R. K., Cobrinik, D., Lee, M. H., & Dyson, N. (1997) · Genes & Development

Cancer-related Molecular PathwaysGenomics and Chromatin Dynamics

Cited by 431

Conserved role of SIRT1 orthologs in fasting-dependent inhibition of the lipid/cholesterol regulator SREBP

Walker, A. K., Yang, F., Jiang, K., Ji, J.-Y., Watts, J. L., Purushotham, A., Boss, O., Hirsch, M. L., Ribich, S., Smith, J. J., et al. (2010) · Genes & Development

Sirtuins and Resveratrol in MedicineCancer, Lipids, and Metabolism

Cited by 357

Retinoblastoma protein partners

Morris, E. J., & Dyson, N. J. (2001) · Advances in Cancer Research

Cancer-related Molecular PathwaysRetinal Development and Disorders

Cited by 349

LKB1 loss links serine metabolism to DNA methylation and tumorigenesis

Kottakis, F., Nicolay, B. N., Roumane, A., Karnik, R., Gu, H., Nagle, J. M., Boukhali, M., Hayward, M. C., Li, Y. Y., Chen, T., et al. (2016) · Nature

Epigenetics and DNA MethylationCancer, Hypoxia, and Metabolism

Cited by 348

The metabolic function of cyclin D3-CDK6 kinase in cancer cell survival

Wang, H., Nicolay, B. N., Chick, J. M., Gao, X., Geng, Y., Ren, H., Gao, H., Yang, G., Williams, J. A., Suski, J. M., et al. (2017) · Nature

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 347

pRB plays an essential role in cell cycle arrest induced by DNA damage

Harrington, E. A., Bruce, J. L., Harlow, E., & Dyson, N. (1998) · Proceedings of the National Academy of Sciences

Cancer-related Molecular PathwaysDNA Repair Mechanisms

Cited by 242

Retinoblastoma protein and anaphase-promoting complex physically interact and functionally cooperate during cell-cycle exit

Binné, U. K., Classon, M. K., Dick, F. A., Wei, W., Rape, M., Kaelin, W. G., Näär, A. M., & Dyson, N. J. (2007) · Nature Cell Biology

Cancer-related Molecular PathwaysUbiquitin and proteasome pathways

Cited by 175

The Retinoblastoma Protein Regulates Pericentric Heterochromatin

Isaac, C. E., Francis, S. M., Martens, A. L., Julian, L. M., Seifried, L. A., Erdmann, N., Binné, U. K., Harrington, L., Sicinski, P., Bérubé, N. G., et al. (2006) · Molecular and Cellular Biology

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 128

RBF1 promotes chromatin condensation through a conserved interaction with the Condensin II protein dCAP-D3

Longworth, M. S., Herr, A., Ji, J.-Y., & Dyson, N. J. (2008) · Genes & Development

Genomics and Chromatin DynamicsMicrotubule and mitosis dynamics

Cited by 122

CDK4/6 and IGF1 receptor inhibitors synergize to suppress the growth of p16INK4A-deficient pancreatic cancers

Heilmann, A. M., Perera, R. M., Ecker, V., Nicolay, B. N., Bardeesy, N., Benes, C. H., & Dyson, N. J. (2014) · Cancer Research

Pancreatic and Hepatic Oncology ResearchAdvanced Breast Cancer Therapies

Cited by 119