Lee, Wyne P.

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

Kayagaki, N., Stowe, I. B., Lee, B. L., O’Rourke, K., Anderson, K., Warming, S., Cuellar, T., Haley, B., Roose-Girma, M., Phung, Q. T., et al. (2015) · Nature

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 3,686

Cryopyrin activates the inflammasome in response to toxins and ATP

Mariathasan, S., Weiss, D. S., Newton, K., McBride, J., O'Rourke, K., Roose-Girma, M., Lee, W. P., Weinrauch, Y., Monack, D. M., & Dixit, V. M. (2006) · Nature

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 3,080

Non-canonical inflammasome activation targets caspase-11

Kayagaki, N., Warming, S., Lamkanfi, M., Walle, L. V., Louie, S., Dong, J., Newton, K., Qu, Y., Liu, J., Heldens, S., et al. (2011) · Nature

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 2,530

NINJ1 mediates plasma membrane rupture during lytic cell death

Kayagaki, N., Kornfeld, O. S., Lee, B. L., Stowe, I. B., O’Rourke, K., Li, Q., Sandoval, W., Yan, D., Kang, J., Xu, M., et al. (2021) · Nature

Cell death mechanisms and regulationInflammasome and immune disorders

Cited by 857

Glyburide inhibits the Cryopyrin/Nalp3 inflammasome

Lamkanfi, M., Mueller, J. L., Vitari, A. C., Misaghi, S., Fedorova, A., Deshayes, K., Lee, W. P., Hoffman, H. M., & Dixit, V. M. (2009) · Journal of Cell Biology

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 820

IL-17C regulates the innate immune function of epithelial cells in an autocrine manner

Ramirez-Carrozzi, V., Sambandam, A., Luis, E., Lin, Z., Jeet, S., Lesch, J., Hackney, J., Kim, J., Zhou, M., Lai, J., et al. (2011) · Nature Immunology

Psoriasis: Treatment and PathogenesisCytokine Signaling Pathways and Interactions

Cited by 477

Specific Btk inhibition suppresses B cell- and myeloid cell-mediated arthritis

Di Paolo, J. A., Huang, T., Balazs, M., Barbosa, J., Barck, K. H., Bravo, B. J., Carano, R. A. D., Darrow, J., Davies, D. R., DeForge, L. E., et al. (2011) · Nature Chemical Biology

Rheumatoid Arthritis Research and TherapiesNatural Compounds in Disease Treatment

Cited by 340

Progranulin deficiency causes impairment of autophagy and TDP-43 accumulation

Chang, M. C., Srinivasan, K., Friedman, B. A., Suto, E., Modrusan, Z., Lee, W. P., Kaminker, J. S., Hansen, D. V., & Sheng, M. (2017) · Journal of Experimental Medicine

Amyotrophic Lateral Sclerosis ResearchAutophagy in Disease and Therapy

Cited by 141

Potassium channels Kv1.3 and KCa3.1 cooperatively and compensatorily regulate antigen-specific memory T cell functions

Chiang, E. Y., Li, T., Jeet, S., Peng, I., Zhang, J., Lee, W. P., DeVoss, J., Caplazi, P., Chen, J., Warming, S., et al. (2017) · Nature Communications

Ion channel regulation and functionT-cell and B-cell Immunology

Cited by 108