Massagué, Joan

Metastasis-Initiating Cells and Ecosystems

Massagué, J., & Ganesh, K. (2021) · Cancer Discovery

Cancer Cells and MetastasisMechanisms of cancer metastasis

Cited by 372

Complement Component 3 adapts the cerebrospinal fluid for leptomeningeal metastasis.

Boire, A., Zou, Y., Shieh, J., Macalinao, D. G., Pentsova, E., & Massagué, J. (2017) · Cell

Brain Metastases and TreatmentComplement system in diseases

Cited by 366

Membrane-anchored and soluble forms of betaglycan, a polymorphic proteoglycan that binds transforming growth factor-beta.

Andres, J. L., Stanley, K., Cheifetz, S., & Massagué, J. (1989) · The Journal of cell biology

Proteoglycans and glycosaminoglycans researchTGF-β signaling in diseases

Cited by 354

Activation of Signalling by the Activin Receptor Complex

Attisano, L., Wrana, J. L., Montalvo, E., & Massagué, J. (1996) · Molecular and Cellular Biology

TGF-β signaling in diseasesProtein Kinase Regulation and GTPase Signaling

Cited by 316

Pericyte-like spreading by disseminated cancer cells activates YAP and MRTF for metastatic colonization

Er, E. E., Valiente, M., Ganesh, K., Zou, Y., Agrawal, S., Hu, J., Griscom, B., Rosenblum, M., Boire, A., Brogi, E., et al. (2018) · Nature Cell Biology

Hippo pathway signaling and YAP/TAZCancer Cells and Metastasis

Cited by 292

Direct Binding of Smad1 and Smad4 to Two Distinct Motifs Mediates Bone Morphogenetic Protein-specific Transcriptional Activation ofId1 Gene

López-Rovira, T., Chalaux, E., Massagué, J., Rosa, J. L., & Ventura, F. (2002) · Journal of Biological Chemistry

TGF-β signaling in diseasesGenomics and Chromatin Dynamics

Cited by 285

Differential interaction of the cyclin-dependent kinase (Cdk) inhibitor p27Kip1 with cyclin A-Cdk2 and cyclin D2-Cdk4

Blain, S. W., Montalvo, E., & Massagué, J. (1997) · Journal of Biological Chemistry

Cancer-related Molecular PathwaysMicrotubule and mitosis dynamics

Cited by 279

Regulation of Cell Adhesion Receptors by Transforming Growth Factor-β

Ignotz, R. A., Heino, J., & Massagué, J. (1989) · Journal of Biological Chemistry

Cell Adhesion Molecules ResearchTGF-β signaling in diseases

Cited by 269

Cell-cell adhesion mediated by binding of membrane-anchored transforming growth factor alpha to epidermal growth factor receptors promotes cell proliferation

Anklesaria, P., Teixidó, J., Laiho, M., Pierce, J. H., Greenberger, J. S., & Massagué, J. (1990) · Proceedings of the National Academy of Sciences

HER2/EGFR in Cancer ResearchCell Adhesion Molecules Research

Cited by 252

Epigenetic expansion of VHL-HIF signal output drives multiorgan metastasis in renal cancer

Vanharanta, S., Shu, W., Brenet, F., Hakimi, A. A., Heguy, A., Viale, A., Reuter, V. E., Hsieh, J. J.-D., Scandura, J. M., & Massagué, J. (2013) · Nature Medicine

Cancer, Hypoxia, and MetabolismRenal cell carcinoma treatment

Cited by 215

Structural Basis for the Versatile Interactions of Smad7 with Regulator WW Domains in TGF-β Pathways

Aragón, E., Goerner, N., Xi, Q., Gomes, T., Gao, S., Massagué, J., & Macias, M. J. (2012) · Structure

TGF-β signaling in diseasesHippo pathway signaling and YAP/TAZ

Cited by 99

ID1 Mediates Escape from TGFβ Tumor Suppression in Pancreatic Cancer

Huang, Y.-H., Hu, J., Chen, F., Lecomte, N., Basnet, H., David, C. J., Witkin, M. D., Allen, P. J., Leach, S. D., Hollmann, T. J., et al. (2020) · Cancer Discovery

TGF-β signaling in diseasesPancreatic and Hepatic Oncology Research

Cited by 78