Massagué, Joan

TGFβ in Cancer

Massagué, J. (2008) · Cell

TGF-β signaling in diseasesMechanisms of cancer metastasis

Cited by 3,907

Genes that mediate breast cancer metastasis to lung

Minn, A. J., Gupta, G. P., Siegel, P. M., Bos, P. D., Shu, W., Giri, D. D., Viale, A., Olshen, A. B., Gerald, W. L., & Massagué, J. (2005) · Nature

Cancer Cells and MetastasisBreast Cancer Treatment Studies

Cited by 2,922

Transforming growth factor-beta stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix.

Ignotz, R. A., & Massagué, J. (1986) · Journal of Biological Chemistry

TGF-β signaling in diseasesCell Adhesion Molecules Research

Cited by 2,492

Transforming Growth Factor-β Signaling in Immunity and Cancer

Batlle, E., & Massagué, J. (2019) · Immunity

TGF-β signaling in diseasesT-cell and B-cell Immunology

Cited by 2,366

Guidelines and definitions for research on epithelial-mesenchymal transition

Yang, J., Antin, P., Berx, G., Blanpain, C., Brabletz, T., Bronner, M., Campbell, K., Cano, A., Casanova, J., Christofori, G., et al. (2020) · Nature Reviews Molecular Cell Biology

Cancer Cells and MetastasisTGF-β signaling in diseases

Cited by 2,226

Metastatic colonization by circulating tumour cells

Massagué, J., & Obenauf, A. C. (2016) · Nature

Cancer Cells and MetastasisMechanisms of cancer metastasis

Cited by 2,062

Genes that mediate breast cancer metastasis to the brain

Bos, P. D., Zhang, X. H.-F., Nadal, C., Shu, W., Gomis, R. R., Nguyen, D. X., Minn, A. J., van de Vijver, M. J., Gerald, W. L., Foekens, J. A., et al. (2009) · Nature

Brain Metastases and TreatmentCancer Cells and Metastasis

Cited by 1,863

TGF-β directly targets cytotoxic T cell functions during tumor evasion of immune surveillance

Thomas, D. A., & Massagué, J. (2005) · Cancer Cell

TGF-β signaling in diseasesT-cell and B-cell Immunology

Cited by 1,355

Tumor Self-Seeding by Circulating Cancer Cells

Kim, M.-Y., Oskarsson, T., Acharyya, S., Nguyen, D. X., Zhang, X. H.-F., Norton, L., & Massagué, J. (2009) · Cell

Cancer Cells and MetastasisCancer Genomics and Diagnostics

Cited by 1,335

A CXCL1 Paracrine Network Links Cancer Chemoresistance and Metastasis

Acharyya, S., Oskarsson, T., Vanharanta, S., Malladi, S., Kim, J., Morris, P. G., Manova-Todorova, K., Leversha, M., Hogg, N., Seshan, V. E., et al. (2012) · Cell

Chemokine receptors and signalingCancer Cells and Metastasis

Cited by 1,085

Dependency of Colorectal Cancer on a TGF-β-Driven Program in Stromal Cells for Metastasis Initiation

Calon, A., Espinet, E., Palomo-Ponce, S., Tauriello, D. V. F., Iglesias, M., Céspedes, M. V., Sevillano, M., Nadal, C., Jung, P., Zhang, X. H.-F., et al. (2012) · Cancer Cell

TGF-β signaling in diseasesCancer Cells and Metastasis

Cited by 1,060

Carcinoma–astrocyte gap junctions promote brain metastasis by cGAMP transfer

Chen, Q., Boire, A., Jin, X., Valiente, M., Er, E. E., Lopez-Soto, A., S. Jacob, L., Patwa, R., Shah, H., Xu, K., et al. (2016) · Nature

Connexins and lens biologyBrain Metastases and Treatment

Cited by 969

Kip/Cip and Ink4 Cdk inhibitors cooperate to induce cell cycle arrest in response to TGF-beta.

Reynisdóttir, I., Polyak, K., Iavarone, A., & Massagué, J. (1995) · Genes & Development

Cancer-related Molecular PathwaysTGF-β signaling in diseases

Cited by 962

TGF-β signaling in health and disease

Massagué, J., & Sheppard, D. (2023) · Cell

TGF-β signaling in diseasesLiver physiology and pathology

Cited by 890

Breast cancer cells produce tenascin C as a metastatic niche component to colonize the lungs

Oskarsson, T., Acharyya, S., Zhang, X. H.-F., Vanharanta, S., Tavazoie, S. F., Morris, P. G., Downey, R. J., Manova-Todorova, K., Brogi, E., & Massagué, J. (2011) · Nature Medicine

Cancer Cells and MetastasisDevelopmental Biology and Gene Regulation

Cited by 869

Contextual determinants of TGFβ action in development, immunity and cancer

David, C. J., & Massagué, J. (2018) · Nature Reviews Molecular Cell Biology

TGF-β signaling in diseasesDevelopmental Biology and Gene Regulation

Cited by 851

Metastatic Latency and Immune Evasion through Autocrine Inhibition of WNT

Malladi, S., Macalinao, D. G., Jin, X., He, L., Basnet, H., Zou, Y., de Stanchina, E., & Massagué, J. (2016) · Cell

Cancer Cells and MetastasisWnt/β-catenin signaling in development and cancer

Cited by 791

Nuclear CDKs Drive Smad Transcriptional Activation and Turnover in BMP and TGF-β Pathways

Alarcón, C., Zaromytidou, A.-I., Xi, Q., Gao, S., Yu, J., Fujisawa, S., Barlas, A., Miller, A. N., Manova-Todorova, K., Macias, M. J., et al. (2009) · Cell

TGF-β signaling in diseasesHippo pathway signaling and YAP/TAZ

Cited by 719

Macrophage binding to receptor VCAM-1 transmits survival signals in breast cancer cells that invade the lungs

Chen, Q., Zhang, X. H.-F., & Massagué, J. (2011) · Cancer Cell

Cell Adhesion Molecules ResearchCancer Cells and Metastasis

Cited by 619

The TGF-beta family mediator Smad1 is phosphorylated directly and activated functionally by the BMP receptor kinase

Kretzschmar, M., Liu, F., Hata, A., Doody, J., & Massagué, J. (1997) · Genes & Development

TGF-β signaling in diseasesDevelopmental Biology and Gene Regulation

Cited by 574

A rectal cancer organoid platform to study individual responses to chemoradiation

Ganesh, K., Wu, C., O’Rourke, K. P., Szeglin, B. C., Zheng, Y., Sauvé, C.-E. G., Adileh, M., Wasserman, I., Marco, M. R., Kim, A. S., et al. (2019) · Nature Medicine

Cancer Cells and MetastasisColorectal Cancer Surgical Treatments

Cited by 569

Origins of Metastatic Traits

Vanharanta, S., & Massagué, J. (2013) · Cancer Cell

Cancer Cells and MetastasisCancer Genomics and Diagnostics

Cited by 563

Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1

Luo, Y., Hurwitz, J., & Massagué, J. (1995) · Nature

Cancer-related Molecular PathwaysDNA Repair Mechanisms

Cited by 549

Lung metastasis genes couple breast tumor size and metastatic spread

Minn, A. J., Gupta, G. P., Padua, D., Bos, P., Nguyen, D. X., Nuyten, D., Kreike, B., Zhang, Y., Wang, Y., Ishwaran, H., et al. (2007) · Proceedings of the National Academy of Sciences

Cancer Cells and MetastasisMechanisms of cancer metastasis

Cited by 400