Gaffney, Patrick M.

Subsistence strategies in traditional societies distinguish gut microbiomes

Obregon-Tito, A. J., Tito, R. Y., Metcalf, J., Sankaranarayanan, K., Clemente, J. C., Ursell, L. K., Zech Xu, Z., Van Treuren, W., Knight, R., Gaffney, P. M., et al. (2015) · Nature Communications

Gut microbiota and healthOral microbiology and periodontitis research

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Three functional variants of IFN regulatory factor 5 ( IRF5 ) define risk and protective haplotypes for human lupus

Graham, R. R., Kyogoku, C., Sigurdsson, S., Vlasova, I. A., Davies, L. R. L., Baechler, E. C., Plenge, R. M., Koeuth, T., Ortmann, W. A., Hom, G., et al. (2007) · Proceedings of the National Academy of Sciences

Systemic Lupus Erythematosus ResearchGenetic Associations and Epidemiology

Cited by 450

Association of a functional variant downstream of TNFAIP3 with systemic lupus erythematosus

Adrianto, I., Wen, F., Templeton, A., Wiley, G., King, J. B., Lessard, C. J., Bates, J. S., Hu, Y., Kelly, J. A., Kaufman, K. M., et al. (2011) · Nature Genetics

Systemic Lupus Erythematosus ResearchGenetic Associations and Epidemiology

Cited by 279

Visualizing Human Leukocyte Antigen Class II Risk Haplotypes in Human Systemic Lupus Erythematosus

Graham, R. R., Ortmann, W. A., Langefeld, C. D., Jawaheer, D., Selby, S. A., Rodine, P. R., Baechler, E. C., Rohlf, K. E., Shark, K. B., Espe, K. J., et al. (2002) · The American Journal of Human Genetics

Systemic Lupus Erythematosus ResearchGenetic Associations and Epidemiology

Cited by 223

Specific combinations of HLA-DR2 and DR3 class II haplotypes contribute graded risk for disease susceptibility and autoantibodies in human SLE

Graham, R. R., Ortmann, W., Rodine, P., Espe, K., Langefeld, C., Lange, E., Williams, A., Beck, S., Kyogoku, C., Moser, K., et al. (2007) · European Journal of Human Genetics

Systemic Lupus Erythematosus ResearchSystemic Sclerosis and Related Diseases

Cited by 174

High-Density SNP Screening of the Major Histocompatibility Complex in Systemic Lupus Erythematosus Demonstrates Strong Evidence for Independent Susceptibility Regions

Barcellos, L. F., May, S. L., Ramsay, P. P., Quach, H. L., Lane, J. A., Nititham, J., Noble, J. A., Taylor, K. E., Quach, D. L., Chung, S. A., et al. (2009) · PLoS Genetics

Systemic Lupus Erythematosus ResearchGenetic Associations and Epidemiology

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An Enhancer Element Harboring Variants Associated with Systemic Lupus Erythematosus Engages the TNFAIP3 Promoter to Influence A20 Expression

Wang, S., Wen, F., Wiley, G. B., Kinter, M. T., & Gaffney, P. M. (2013) · PLoS Genetics

Systemic Lupus Erythematosus ResearchGenomics and Chromatin Dynamics

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Enhancer histone-QTLs are enriched on autoimmune risk haplotypes and influence gene expression within chromatin networks

Pelikan, R. C., Kelly, J. A., Fu, Y., Lareau, C. A., Tessneer, K. L., Wiley, G. B., Wiley, M. M., Glenn, S. B., Harley, J. B., Guthridge, J. M., et al. (2018) · Nature Communications

Genomics and Chromatin DynamicsGenetic Associations and Epidemiology

Cited by 94

Chromatin Looping Links Target Genes with Genetic Risk Loci for Dermatological Traits

Shi, C., Ray-Jones, H., Ding, J., Duffus, K., Fu, Y., Gaddi, V. P., Gough, O., Hankinson, J., Martin, P., McGovern, A., et al. (2021) · Journal of Investigative Dermatology

Genomics and Chromatin DynamicsGenetic Associations and Epidemiology

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Mapping DNA interaction landscapes in psoriasis susceptibility loci highlights KLF4 as a target gene in 9q31

Ray-Jones, H., Duffus, K., McGovern, A., Martin, P., Shi, C., Hankinson, J., Gough, O., Yarwood, A., Morris, A. P., Adamson, A., et al. (2020) · BMC Biology

Psoriasis: Treatment and PathogenesisGenomics and Chromatin Dynamics

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