Rubin, Lee L.

Vascular and Neurogenic Rejuvenation of the Aging Mouse Brain by Young Systemic Factors

Katsimpardi, L., Litterman, N. K., Schein, P. A., Miller, C. M., Loffredo, F. S., Wojtkiewicz, G. R., Chen, J. W., Lee, R. T., Wagers, A. J., & Rubin, L. L. (2014) · Science

Neurogenesis and neuroplasticity mechanismsBarrier Structure and Function Studies

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A Small-Molecule Inhibitor of Tgf-β Signaling Replaces Sox2 in Reprogramming by Inducing Nanog

Ichida, J. K., Blanchard, J., Lam, K., Son, E. Y., Chung, J. E., Egli, D., Loh, K. M., Carter, A. C., Di Giorgio, F. P., Koszka, K., et al. (2009) · Cell Stem Cell

Pluripotent Stem Cells ResearchDevelopmental Biology and Gene Regulation

Cited by 808

Single-cell transcriptomic profiling of the aging mouse brain

Ximerakis, M., Lipnick, S. L., Innes, B. T., Simmons, S. K., Adiconis, X., Dionne, D., Mayweather, B. A., Nguyen, L., Niziolek, Z., Ozek, C., et al. (2019) · Nature Neuroscience

Single-cell and spatial transcriptomicsGenetics, Aging, and Longevity in Model Organisms

Cited by 736

In Silico Labeling: Predicting Fluorescent Labels in Unlabeled Images

Christiansen, E. M., Yang, S. J., Ando, D. M., Javaherian, A., Skibinski, G., Lipnick, S., Mount, E., O’Neil, A., Shah, K., Lee, A. K., et al. (2018) · Cell

Cell Image Analysis TechniquesAdvanced Fluorescence Microscopy Techniques

Cited by 635

SMN2 splicing modifiers improve motor function and longevity in mice with spinal muscular atrophy

Naryshkin, N. A., Weetall, M., Dakka, A., Narasimhan, J., Zhao, X., Feng, Z., Ling, K. K. Y., Karp, G. M., Qi, H., Woll, M. G., et al. (2014) · Science

Neurogenetic and Muscular Disorders ResearchAmyotrophic Lateral Sclerosis Research

Cited by 524

Reactive Astrocytes Promote ALS-like Degeneration and Intracellular Protein Aggregation in Human Motor Neurons by Disrupting Autophagy through TGF-β1

Tripathi, P., Rodriguez-Muela, N., Klim, J. R., de Boer, A. S., Agrawal, S., Sandoe, J., Lopes, C. S., Ogliari, K. S., Williams, L. A., Shear, M., et al. (2017) · Stem Cell Reports

Amyotrophic Lateral Sclerosis ResearchAlzheimer's disease research and treatments

Cited by 123

Material Microenvironmental Properties Couple to Induce Distinct Transcriptional Programs in Mammalian Stem Cells

Darnell, M., O’Neil, A., Mao, A., Gu, L., Rubin, L. L., & Mooney, D. J. (2018) · Proceedings of the National Academy of Sciences

Cellular Mechanics and InteractionsHydrogels: synthesis, properties, applications

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Applying Deep Neural Network Analysis to High-Content Image-Based Assays

Yang, S. J., Lipnick, S. L., Makhortova, N. R., Venugopalan, S., Fan, M., Armstrong, Z., Schlaeger, T. M., Deng, L., Chung, W. K., O’Callaghan, L., et al. (2019) · SLAS DISCOVERY

Cell Image Analysis TechniquesSingle-cell and spatial transcriptomics

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Genetic modifiers ameliorate endocytic and neuromuscular defects in a model of spinal muscular atrophy

Walsh, M. B., Janzen, E., Wingrove, E., Hosseinibarkooie, S., Muela, N. R., Davidow, L., Dimitriadi, M., Norabuena, E. M., Rubin, L. L., Wirth, B., et al. (2020) · BMC Biology

Neurogenetic and Muscular Disorders ResearchAmyotrophic Lateral Sclerosis Research

Cited by 22

Activated GDF11/8 subforms predict cardiovascular events and mortality in humans

Walker, R. G., Kato, T., Ben Driss, L., Williams, S. A., Hinterberg, M. A., Janjic, N., Gelinas, A. D., Carpenter, M. A., Kattamuri, C., Walter, J. E., et al. (2025) · Nature Communications

GDF15 and Related BiomarkersTGF-β signaling in diseases

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