Markus, Hugh S.

Prediction of Clinical Cardiovascular Events With Carotid Intima-Media Thickness: A Systematic Review and Meta-Analysis

Lorenz, M. W., Markus, H. S., Bots, M. L., Rosvall, M., & Sitzer, M. (2007) · Circulation

Cardiovascular Health and Disease PreventionCerebrovascular and Carotid Artery Diseases

Cited by 2,977

The clinical importance of white matter hyperintensities on brain magnetic resonance imaging: systematic review and meta-analysis

Debette, S., & Markus, H. S. (2010) · BMJ

Cerebrovascular and genetic disordersDementia and Cognitive Impairment Research

Cited by 2,328

Analysis of shared heritability in common disorders of the brain

The Brainstorm Consortium, Anttila, V., Bulik-Sullivan, B., Finucane, H. K., Walters, R. K., Bras, J., Duncan, L., Escott-Price, V., Falcone, G. J., Gormley, P., et al. (2018) · Science

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 1,924

Neuroimaging standards for research into small vessel disease—advances since 2013

Duering, M., Biessels, G. J., Brodtmann, A., Chen, C., Cordonnier, C., de Leeuw, F.-E., Debette, S., Frayne, R., Jouvent, E., Rost, N. S., et al. (2023) · The Lancet Neurology

Cerebrovascular and genetic disordersNeurological Disease Mechanisms and Treatments

Cited by 1,144

Vascular dysfunction—The disregarded partner of Alzheimer's disease

Sweeney, M. D., Montagne, A., Sagare, A. P., Nation, D. A., Schneider, L. S., Chui, H. C., Harrington, M. G., Pa, J., Law, M., Wang, D. J. J., et al. (2019) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchNeurological Disease Mechanisms and Treatments

Cited by 711

A sequence variant in ZFHX3 on 16q22 associates with atrial fibrillation and ischemic stroke

Gudbjartsson, D. F., Holm, H., Gretarsdottir, S., Thorleifsson, G., Walters, G. B., Thorgeirsson, G., Gulcher, J., Mathiesen, E. B., Njølstad, I., Nyrnes, A., et al. (2009) · Nature Genetics

Atrial Fibrillation Management and OutcomesGenetic Associations and Epidemiology

Cited by 489

Genetic Heritability of Ischemic Stroke and the Contribution of Previously Reported Candidate Gene and Genomewide Associations

Bevan, S., Traylor, M., Adib-Samii, P., Malik, R., Paul, N. L. M., Jackson, C., Farrall, M., Rothwell, P. M., Sudlow, C., Dichgans, M., et al. (2012) · Stroke

Genetic Associations and EpidemiologyAcute Ischemic Stroke Management

Cited by 395

Modifiable pathways in Alzheimer’s disease: Mendelian randomisation analysis

Larsson, S. C., Traylor, M., Malik, R., Dichgans, M., Burgess, S., & Markus, H. S. (2017) · BMJ

Dementia and Cognitive Impairment ResearchGenetic Associations and Epidemiology

Cited by 382

MRI hyperintensities of the temporal lobe and external capsule in patients with CADASIL

O’Sullivan, M., Jarosz, J. M., Martin, R. J., Deasy, N., Powell, J. F., & Markus, H. S. (2001) · Neurology

Cerebrovascular and genetic disordersIntracerebral and Subarachnoid Hemorrhage Research

Cited by 363

Patterns of cerebral blood flow reduction in patients with ischemic leukoaraiosis

O’Sullivan, M., Lythgoe, D. J., Pereira, A. C., Summers, P. E., Jarosz, J. M., Williams, S. C. R., & Markus, H. S. (2002) · Neurology

Cerebrovascular and genetic disordersAdvanced MRI Techniques and Applications

Cited by 360

White matter damage on diffusion tensor imaging correlates with age-related cognitive decline

Charlton, R. A., Barrick, T. R., McIntyre, D. J., Shen, Y., O'Sullivan, M., Howe, F. A., Clark, C. A., Morris, R. G., & Markus, H. S. (2006) · Neurology

Advanced Neuroimaging Techniques and ApplicationsDementia and Cognitive Impairment Research

Cited by 354

Diagnostic strategies in CADASIL

Markus, H. S., Martin, R. J., Simpson, M. A., Dong, Y. B., Ali, N., Crosby, A. H., & Powell, J. F. (2002) · Neurology

Cerebrovascular and genetic disordersMigraine and Headache Studies

Cited by 335

Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension

CHARGE-Heart Failure Consortium, Surendran, P., EchoGen Consortium, METASTROKE Consortium, GIANT Consortium, EPIC-InterAct Consortium, Study, L. C., Wellcome Trust Case Control Consortium, Understanding Society Scientific Group, EPIC-CVD Consortium, et al. (2016) · Nature Genetics

Genetic Associations and EpidemiologyBlood Pressure and Hypertension Studies

Cited by 312

Structural network efficiency is associated with cognitive impairment in small-vessel disease

Lawrence, A. J., Chung, A. W., Morris, R. G., Markus, H. S., & Barrick, T. R. (2014) · Neurology

Advanced Neuroimaging Techniques and ApplicationsFunctional Brain Connectivity Studies

Cited by 285

Blood-brain barrier permeability is increased in normal-appearing white matter in patients with lacunar stroke and leucoaraiosis

Topakian, R., Barrick, T. R., Howe, F. A., & Markus, H. S. (2010) · Journal of Neurology, Neurosurgery & Psychiatry

Cerebrovascular and genetic disordersBarrier Structure and Function Studies

Cited by 281

Donepezil in patients with subcortical vascular cognitive impairment: a randomised double-blind trial in CADASIL

Dichgans, M., Markus, H. S., Salloway, S., Verkkoniemi, A., Moline, M., Wang, Q., Posner, H., & Chabriat, H. S. (2008) · The Lancet Neurology

Dementia and Cognitive Impairment ResearchNeurological Disease Mechanisms and Treatments

Cited by 264

Do in vivo Experimental Models Reflect Human Cerebral Small Vessel Disease? a Systematic Review

Hainsworth, A. H., & Markus, H. S. (2008) · Journal of Cerebral Blood Flow & Metabolism

Cerebrovascular and genetic disordersNeurological Disease Mechanisms and Treatments

Cited by 240

Clinical Spectrum of CADASIL and the Effect of Cardiovascular Risk Factors on Phenotype: Study in 200 Consecutively Recruited Individuals

Adib-Samii, P., Brice, G., Martin, R. J., & Markus, H. S. (2010) · Stroke

Cerebrovascular and genetic disordersMigraine and Headache Studies

Cited by 239

Common variation in PHACTR1 is associated with susceptibility to cervical artery dissection

International Stroke Genetics Consortium, Debette, S., the CADISP group, Kamatani, Y., Metso, T. M., Kloss, M., Chauhan, G., Engelter, S. T., Pezzini, A., Thijs, V., et al. (2015) · Nature Genetics

Cerebrovascular and Carotid Artery DiseasesGenetic Associations and Epidemiology

Cited by 231

Meta-analysis of genome-wide association studies from the CHARGE consortium identifies common variants associated with carotid intima media thickness and plaque

the CARDIoGRAM Consortium, Bis, J. C., Kavousi, M., Franceschini, N., Isaacs, A., Abecasis, G. R., Schminke, U., Post, W. S., Smith, A. V., Cupples, L. A., et al. (2011) · Nature Genetics

Genetic Associations and EpidemiologyCardiovascular Health and Disease Prevention

Cited by 212

Reduced cerebral blood flow in white matter in ischaemic leukoaraiosis demonstrated using quantitative exogenous contrast based perfusion MRI

Markus, H. S. (2000) · Journal of Neurology, Neurosurgery & Psychiatry

Advanced MRI Techniques and ApplicationsCerebrovascular and genetic disorders

Cited by 202

Investigating the Causal Relationship of C-Reactive Protein with 32 Complex Somatic and Psychiatric Outcomes: A Large-Scale Cross-Consortium Mendelian Randomization Study

Prins, B. P., Abbasi, A., Wong, A., Vaez, A., Nolte, I., Franceschini, N., Stuart, P. E., Guterriez Achury, J., Mistry, V., Bradfield, J. P., et al. (2016) · PLOS Medicine

Genetic Associations and EpidemiologyAdipokines, Inflammation, and Metabolic Diseases

Cited by 199

Markers of Endothelial and Hemostatic Activation and Progression of Cerebral White Matter Hyperintensities: Longitudinal Results of the Austrian Stroke Prevention Study

Markus, H. S., Hunt, B., Palmer, K., Enzinger, C., Schmidt, H., & Schmidt, R. (2005) · Stroke

Cerebrovascular and genetic disordersAcute Ischemic Stroke Management

Cited by 193

The effect of NOTCH3 pathogenic variant position on CADASIL disease severity: NOTCH3 EGFr 1-6 pathogenic variant are associated with a more severe phenotype and lower survival compared with EGFr 7-34 pathogenic variant

Rutten, J. W., Van Eijsden, B. J., Duering, M., Jouvent, E., Opherk, C., Pantoni, L., Federico, A., Dichgans, M., Markus, H. S., Chabriat, H., et al. (2019) · Genetics in Medicine

Cerebrovascular and genetic disordersGenetic Neurodegenerative Diseases

Cited by 169