Schwab, Matthias

Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation

Zanger, U. M., & Schwab, M. (2013) · Pharmacology & Therapeutics

Pharmacogenetics and Drug MetabolismDrug Transport and Resistance Mechanisms

Cited by 4,169

Metformin improves healthspan and lifespan in mice

Martin-Montalvo, A., Mercken, E. M., Mitchell, S. J., Palacios, H. H., Mote, P. L., Scheibye-Knudsen, M., Gomes, A. P., Ward, T. M., Minor, R. K., Blouin, M.-J., et al. (2013) · Nature Communications

Genetics, Aging, and Longevity in Model OrganismsMetabolism, Diabetes, and Cancer

Cited by 1,445

Prenatal developmental origins of behavior and mental health: The influence of maternal stress in pregnancy

Van den Bergh, B. R. H., van den Heuvel, M. I., Lahti, M., Braeken, M., de Rooij, S. R., Entringer, S., Hoyer, D., Roseboom, T., Räikkönen, K., King, S., et al. (2020) · Neuroscience & Biobehavioral Reviews

Maternal Mental Health During Pregnancy and PostpartumBirth, Development, and Health

Cited by 1,181

Siponimod versus placebo in secondary progressive multiple sclerosis (EXPAND): a double-blind, randomised, phase 3 study

Kappos, L., Bar-Or, A., Cree, B. A. C., Fox, R. J., Giovannoni, G., Gold, R., Vermersch, P., Arnold, D. L., Arnould, S., Scherz, T., et al. (2018) · The Lancet

Multiple Sclerosis Research StudiesSphingolipid Metabolism and Signaling

Cited by 942

Telomere length in different tissues of elderly patients

Friedrich, U., Griese, E.-U., Schwab, M., Fritz, P., Thon, K.-P., & Klotz, U. (2000) · Mechanisms of Ageing and Development

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 325

Expression polymorphism of the blood???brain barrier component P-glycoprotein (MDR1) in relation to Parkinson's disease

Furuno, T., Landi, M.-T., Ceroni, M., Caporaso, N., Bernucci, I., Nappi, G., Martignoni, E., Schaeffeler, E., Eichelbaum, M., Schwab, M., et al. (2002) · Pharmacogenetics

Drug Transport and Resistance MechanismsParkinson's Disease Mechanisms and Treatments

Cited by 178

Omics and Drug Response

Meyer, U. A., Zanger, U. M., & Schwab, M. (2013) · Annual Review of Pharmacology and Toxicology

Pharmacogenetics and Drug MetabolismNutrition, Genetics, and Disease

Cited by 157

In vivo genome editing using nuclease-encoding mRNA corrects SP-B deficiency

Mahiny, A. J., Dewerth, A., Mays, L. E., Alkhaled, M., Mothes, B., Malaeksefat, E., Loretz, B., Rottenberger, J., Brosch, D. M., Reautschnig, P., et al. (2015) · Nature Biotechnology

CRISPR and Genetic EngineeringVirus-based gene therapy research

Cited by 139

Organic anion transporters and their implications in pharmacotherapy

Emami Riedmaier, A., Nies, A. T., Schaeffeler, E., & Schwab, M. (2012) · Pharmacological Reviews

Drug Transport and Resistance MechanismsPharmacogenetics and Drug Metabolism

Cited by 128

Modified Foxp3 mRNA protects against asthma through an IL-10-dependent mechanism

Mays, L. E., Ammon-Treiber, S., Mothes, B., Alkhaled, M., Rottenberger, J., Müller-Hermelink, E. S., Grimm, M., Mezger, M., Beer-Hammer, S., von Stebut, E., et al. (2013) · Journal of Clinical Investigation

Asthma and respiratory diseasesAllergic Rhinitis and Sensitization

Cited by 113

Efficacy and Safety of Masitinib in Progressive Forms of Multiple Sclerosis: A Randomized, Phase 3, Clinical Trial

Vermersch, P., Brieva-Ruiz, L., Fox, R. J., Paul, F., Ramio-Torrenta, L., Schwab, M., Moussy, A., Mansfield, C., Hermine, O., Maciejowski, M., et al. (2022) · Neurology Neuroimmunology & Neuroinflammation

Multiple Sclerosis Research StudiesPolyomavirus and related diseases

Cited by 74

First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure

Zwirner, S., Abu Rmilah, A. A., Klotz, S., Pfaffenroth, B., Kloevekorn, P., Moschopoulou, A. A., Schuette, S., Haag, M., Selig, R., Li, K., et al. (2024) · Cell

Liver physiology and pathologyTissue Engineering and Regenerative Medicine

Cited by 65

Physiologically Based Precision Dosing Approach for Drug‐Drug‐Gene Interactions: A Simvastatin Network Analysis

Wojtyniak, J., Selzer, D., Schwab, M., & Lehr, T. (2021) · Clinical Pharmacology & Therapeutics

Pharmacogenetics and Drug MetabolismPharmaceutical studies and practices

Cited by 38

Immunogenomic determinants of exceptional response to immune checkpoint inhibition in renal cell carcinoma

Jammihal, T., Saliby, R. M., Labaki, C., Soulati, H., Gallegos, J., Peris, A., McCurry, D., Yu, C., Shah, V., Poduval, D., et al. (2025) · Nature Cancer

Cancer Immunotherapy and BiomarkersRenal cell carcinoma treatment

Cited by 38

The value of walking: A systematic review on mobility and healthcare costs

Wohlrab, M., Klenk, J., Delgado-Ortiz, L., Chambers, M., Rochester, L., Zuchowski, M., Schwab, M., Becker, C., & Jaeger, S. U. (2022) · European Review of Aging and Physical Activity

Health Systems, Economic Evaluations, Quality of LifeBalance, Gait, and Falls Prevention

Cited by 26

Is laboratory medicine ready for the era of personalized medicine? A survey addressed to laboratory directors of hospitals/academic schools of medicine in Europe

Malentacchi, F., Mancini, I., Brandslund, I., Vermeersch, P., Schwab, M., Marc, J., van Schaik, R. H. N., Siest, G., Theodorsson, E., Pazzagli, M., et al. (2015) · Clinical Chemistry and Laboratory Medicine (CCLM)

Clinical Laboratory Practices and Quality ControlPharmacogenetics and Drug Metabolism

Cited by 16

Open letter on access to the BIA 10-2474 clinical trial data

Brøsen, K., Funck-Brentano, C., Kroemer, H. K., Pirmohamed, M., & Schwab, M. (2017) · The Lancet

Ethics in Clinical ResearchBiomedical Ethics and Regulation

Cited by 12

'A distinct circular DNA profile intersects with proteome changes in the genotoxic stress-related hSOD1G93A model of ALS'

Gerovska, D., Noer, J. B., Qin, Y., Ain, Q., Januzi, D., Schwab, M., Witte, O. W., Araúzo-Bravo, M. J., & Kretz, A. (2023) · Cell & Bioscience

Amyotrophic Lateral Sclerosis ResearchCircular RNAs in diseases

Cited by 7

A distinct circular DNA profile intersects with proteome changes in the genotoxic stress-related hSOD1G93A model of ALS

Gerovska, D., Noer, J. B., Qin, Y., Ain, Q., Januzi, D., Schwab, M., Witte, O. W., Araúzo-Bravo, M. J., & Kretz, A. (2023) · Cell & Bioscience

Amyotrophic Lateral Sclerosis ResearchCircular RNAs in diseases

Cited by 7