Is laboratory medicine ready for the era of personalized medicine? A survey addressed to laboratory directors of hospitals/academic schools of medicine in Europe
Open accessAbstract
Developments in “-omics” are creating a paradigm shift in laboratory medicine leading to personalized medicine. This allows the increase in diagnostics and therapeutics focused on individuals rather than populations. In order to investigate whether laboratory medicine is ready to play a key role in the integration of personalized medicine in routine health care and set the state-of-the-art knowledge about personalized medicine and laboratory medicine in Europe, a questionnaire was constructed under the auspices of the European Federation of Clinical Chemistry and Laboratory Medicine (EFLM) and the European Society of Pharmacogenomics and Personalised Therapy (ESPT). The answers of the participating laboratory medicine professionals indicate that they are aware that personalized medicine can represent a new and promising health model, and that laboratory medicine should play a key role in supporting the implementation of personalized medicine in the clinical setting. Participants think that the current organization of laboratory medicine needs additional/relevant implementations such as (i) new technological facilities in -omics; (ii) additional training for the current personnel focused on the new methodologies; (iii) incorporation in the laboratory of new competencies in data interpretation and counseling; and (iv) cooperation and collaboration among professionals of different disciplines to integrate information according to a personalized medicine approach.
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- Authors
- Malentacchi, F., Mancini, I., Brandslund, I., Vermeersch, P., Schwab, M., Marc, J., van Schaik, R. H. N., Siest, G., Theodorsson, E., Pazzagli, M., Di Resta, C., & Federatio, O. B. O. T. E.
- Affiliations
- University of Florence (IT)
- University of Southern Denmark (DK)
- Universitair Ziekenhuis Leuven (BE)
- Dr. Margarete Fischer-Bosch-Institute of Clinical Pharmacology (DE)
- University of Ljubljana (SI)
- Linköping University (SE)
- Corresponding author
- Malentacchi, Francesca
- ORCID
- Venue
- Clinical Chemistry and Laboratory Medicine (CCLM)
- Publisher
- Walter de Gruyter GmbH
- Published
- 2015-01-01
- Volume
- 53
- Issue
- 7
- Pages
- 981-8
- ISSN
- 1434-6621 (ISSN-L)
- 1437-4331
- OpenAlex
- W4242811878
- Cited by
- 16
- References
- 18
- Citations by year
- 2026: 1 · 2023: 1 · 2022: 2 · 2021: 3 · 2020: 2 · 2019: 3 · 2018: 2 · 2016: 1 · 2015: 1
- FWCI
- 0.98
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- Clinical Chemistry and Laboratory Medicine (CCLM) (publishedVersion)
- PubMed (publishedVersion)
- EUR Research Repository (Erasmus University Rotterdam) (publishedVersion)
- EUR Research Repository (Erasmus University Rotterdam) (submittedVersion)
- Florence Research (University of Florence) (submittedVersion)
- Archivio Istituzionale della Ricerca - Università Vita-Salute San Raffaele (submittedVersion)
- Lirias (submittedVersion)
- University of Southern Denmark Research Portal (University of Southern Denmark) (submittedVersion)
- Funders
- Robert Bosch Stiftung (SCHW858/1-1)
- Deutsche Forschungsgemeinschaft (KFO 274, SCHW858/1-1)
- Bundesministerium für Bildung und Forschung (0315755)
- Topics
- Health Sciences › Medicine › Physiology › Clinical Laboratory Practices and Quality Control
- Life Sciences › Pharmacology, Toxicology and Pharmaceutics › Pharmacology › Pharmacogenetics and Drug Metabolism
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Genomics and Rare Diseases
- Keywords
- personalized medicine, clinical pathology, omics technologies, laboratory directors, laboratory organization, employee training, interdisciplinary collaboration, pharmacogenomics, Europe
- MeSH terms
- Education, Medical, Europe, Hospitals, Humans, Laboratories, Surveys and Questionnaires, Schools, Medical, Societies, Medical, Clinical Laboratory Techniques, Precision Medicine
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