Margittai, Martin

Small Misfolded Tau Species Are Internalized via Bulk Endocytosis and Anterogradely and Retrogradely Transported in Neurons

Wu, J. W., Herman, M., Liu, L., Simoes, S., Acker, C. M., Figueroa, H., Steinberg, J. I., Margittai, M., Kayed, R., Zurzolo, C., et al. (2013) · Journal of Biological Chemistry

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 537

Single-molecule fluorescence resonance energy transfer reveals a dynamic equilibrium between closed and open conformations of syntaxin 1

Margittai, M., Widengren, J., Schweinberger, E., Schröder, G. F., Felekyan, S., Haustein, E., König, M., Fasshauer, D., Grubmüller, H., Jahn, R., et al. (2003) · Proceedings of the National Academy of Sciences

Cellular transport and secretionAdvanced Fluorescence Microscopy Techniques

Cited by 290

Variations in filament conformation dictate seeding barrier between three- and four-repeat Tau

Dinkel, P. D., Siddiqua, A., Huynh, H., Shah, M., & Margittai, M. (2011) · Biochemistry

Alzheimer's disease research and treatmentsPrion Diseases and Protein Misfolding

Cited by 104

Conformational basis for asymmetric seeding barrier in filaments of three- and four-repeat tau

Siddiqua, A., Luo, Y., Meyer, V., Swanson, M. A., Yu, X., Wei, G., Zheng, J., Eaton, G. R., Ma, B., Nussinov, R., et al. (2012) · Journal of the American Chemical Society

Alzheimer's disease research and treatmentsElectron Spin Resonance Studies

Cited by 75

Structural disorder in four-repeat Tau fibrils reveals a new mechanism for barriers to cross-seeding of Tau isoforms

Weismiller, H. A., Murphy, R., Wei, G., Ma, B., Nussinov, R., & Margittai, M. (2018) · Journal of Biological Chemistry

Alzheimer's disease research and treatmentsPrion Diseases and Protein Misfolding

Cited by 44

Single Mutations in Tau Modulate the Populations of Fibril Conformers through Seed Selection

Meyer, V., Dinkel, P. D., Luo, Y., Yu, X., Wei, G., Zheng, J., Eaton, G. R., Ma, B., Nussinov, R., Eaton, S. S., et al. (2014) · Angewandte Chemie International Edition

Alzheimer's disease research and treatmentsPrion Diseases and Protein Misfolding

Cited by 42

MAP2 caps tau fibrils and inhibits aggregation

Holden, M. R., Krzesinski, B. J., Weismiller, H. A., Shady, J. R., & Margittai, M. (2023) · Journal of Biological Chemistry

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 13