Drucker, Daniel J.

Diabetes, obesity, metabolism, and SARS-CoV-2 infection: the end of the beginning

Drucker, D. J. (2021) · Cell Metabolism

COVID-19 Clinical Research StudiesSARS-CoV-2 and COVID-19 Research

Cited by 272

Incretin Action in the Pancreas: Potential Promise, Possible Perils, and Pathological Pitfalls

Drucker, D. J. (2013) · Diabetes

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 272

The Glucagon Receptor Is Required for the Adaptive Metabolic Response to Fasting

Longuet, C., Sinclair, E. M., Maida, A., Baggio, L. L., Maziarz, M., Charron, M. J., & Drucker, D. J. (2008) · Cell Metabolism

Peroxisome Proliferator-Activated ReceptorsLipid metabolism and disorders

Cited by 272

Islet α cells and glucagon--critical regulators of energy homeostasis

Campbell, J. E., & Drucker, D. J. (2015) · Nature Reviews Endocrinology

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 266

A Glucagon-Like Peptide-1 Analog Reverses the Molecular Pathology and Cardiac Dysfunction of a Mouse Model of Obesity

Noyan-Ashraf, M. H., Shikatani, E. A., Schuiki, I., Mukovozov, I., Wu, J., Li, R.-K., Volchuk, A., Robinson, L. A., Billia, F., Drucker, D. J., et al. (2013) · Circulation

Cardiovascular Function and Risk FactorsCardiac Fibrosis and Remodeling

Cited by 259

Glucagon-like peptide-1 receptors in the brain: controlling food intake and body weight

Baggio, L. L., & Drucker, D. J. (2014) · Journal of Clinical Investigation

Regulation of Appetite and ObesityDiabetes Treatment and Management

Cited by 245

Beyond the pancreas: contrasting cardiometabolic actions of GIP and GLP1

Hammoud, R., & Drucker, D. J. (2023) · Nature Reviews Endocrinology

Diabetes Treatment and ManagementRegulation of Appetite and Obesity

Cited by 244

The expanding incretin universe: from basic biology to clinical translation

Drucker, D. J., & Holst, J. J. (2023) · Diabetologia

Diabetes Treatment and ManagementPancreatic function and diabetes

Cited by 243

Enteroendocrine L Cells Sense LPS after Gut Barrier Injury to Enhance GLP-1 Secretion

Lebrun, L. J., Lenaerts, K., Kiers, D., Pais de Barros, J.-P., Le Guern, N., Plesnik, J., Thomas, C., Bourgeois, T., Dejong, C. H. C., Kox, M., et al. (2017) · Cell Reports

Diabetes Treatment and ManagementImmune Response and Inflammation

Cited by 238

GLP-1 release and vagal afferent activation mediate the beneficial metabolic and chronotherapeutic effects of D-allulose

Iwasaki, Y., Sendo, M., Dezaki, K., Hira, T., Sato, T., Nakata, M., Goswami, C., Aoki, R., Arai, T., Kumari, P., et al. (2018) · Nature Communications

Regulation of Appetite and ObesityDiabetes Treatment and Management

Cited by 200

Liraglutide

Drucker, D. J., Dritselis, A., & Kirkpatrick, P. (2010) · Nature Reviews Drug Discovery

Diabetes Treatment and ManagementDiabetes Management and Research

Cited by 181

Liraglutide Promotes Natriuresis but Does Not Increase Circulating Levels of Atrial Natriuretic Peptide in Hypertensive Subjects With Type 2 Diabetes

Lovshin, J. A., Barnie, A., DeAlmeida, A., Logan, A., Zinman, B., & Drucker, D. J. (2015) · Diabetes Care

Diabetes Treatment and ManagementBlood Pressure and Hypertension Studies

Cited by 168

Glucagon-like peptide-1 receptor signalling selectively regulates murine lymphocyte proliferation and maintenance of peripheral regulatory T cells

Hadjiyanni, I., Siminovitch, K. A., Danska, J. S., & Drucker, D. J. (2010) · Diabetologia

T-cell and B-cell ImmunologyDiabetes Treatment and Management

Cited by 166

Lipopolysaccharides-Mediated Increase in Glucose-Stimulated Insulin Secretion: Involvement of the GLP-1 Pathway

Nguyen, A. T., Mandard, S., Dray, C., Deckert, V., Valet, P., Besnard, P., Drucker, D. J., Lagrost, L., & Grober, J. (2014) · Diabetes

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 161

BI 456906: Discovery and preclinical pharmacology of a novel GCGR/GLP-1R dual agonist with robust anti-obesity efficacy

Zimmermann, T., Thomas, L., Baader-Pagler, T., Haebel, P., Simon, E., Reindl, W., Bajrami, B., Rist, W., Uphues, I., Drucker, D. J., et al. (2022) · Molecular Metabolism

Regulation of Appetite and ObesityPharmacology and Obesity Treatment

Cited by 149

Glucagon-like peptide-1 receptor signaling modifies the extent of diabetic kidney disease through dampening the receptor for advanced glycation end products–induced inflammation

Sourris, K. C., Ding, Y., Maxwell, S. S., Al-sharea, A., Kantharidis, P., Mohan, M., Rosado, C. J., Penfold, S. A., Haase, C., Xu, Y., et al. (2024) · Kidney International

Advanced Glycation End Products researchChronic Kidney Disease and Diabetes

Cited by 143

TCF1 links GIPR signaling to the control of beta cell function and survival

Campbell, J. E., Ussher, J. R., Mulvihill, E. E., Kolic, J., Baggio, L. L., Cao, X., Liu, Y., Lamont, B. J., Morii, T., Streutker, C. J., et al. (2016) · Nature Medicine

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 142

Gut-Proglucagon-Derived Peptides Are Essential for Regulating Glucose Homeostasis in Mice

Song, Y., Koehler, J. A., Baggio, L. L., Powers, A. C., Sandoval, D. A., & Drucker, D. J. (2019) · Cell Metabolism

Diabetes Treatment and ManagementPancreatic function and diabetes

Cited by 140

Divergent roles for the gut intraepithelial lymphocyte GLP-1R in control of metabolism, microbiota, and T cell-induced inflammation

Wong, C. K., Yusta, B., Koehler, J. A., Baggio, L. L., McLean, B. A., Matthews, D., Seeley, R. J., & Drucker, D. J. (2022) · Cell Metabolism

Diabetes Treatment and ManagementGut microbiota and health

Cited by 138

Modulation of Taste Sensitivity by GLP‐1 Signaling in Taste Buds

Martin, B., Dotson, C. D., Shin, Y., Ji, S., Drucker, D. J., Maudsley, S., & Munger, S. D. (2009) · Annals of the New York Academy of Sciences

Biochemical Analysis and Sensing TechniquesOlfactory and Sensory Function Studies

Cited by 137

An Albumin-Exendin-4 Conjugate Engages Central and Peripheral Circuits Regulating Murine Energy and Glucose Homeostasis

Baggio, L. L., Huang, Q., Cao, X., & Drucker, D. J. (2008) · Gastroenterology

Diabetes Treatment and ManagementRegulation of Appetite and Obesity

Cited by 137

The Hypothalamic Glucagon-Like Peptide 1 Receptor Is Sufficient but Not Necessary for the Regulation of Energy Balance and Glucose Homeostasis in Mice

Burmeister, M. A., Ayala, J. E., Smouse, H., Landivar-Rocha, A., Brown, J. D., Drucker, D. J., Stoffers, D. A., Sandoval, D. A., Seeley, R. J., & Ayala, J. E. (2017) · Diabetes

Regulation of Appetite and ObesityDiabetes Treatment and Management

Cited by 136

GLP-1R Agonists Promote Normal and Neoplastic Intestinal Growth through Mechanisms Requiring Fgf7

Koehler, J. A., Baggio, L. L., Yusta, B., Longuet, C., Rowland, K. J., Cao, X., Holland, D., Brubaker, P. L., & Drucker, D. J. (2015) · Cell Metabolism

Fibroblast Growth Factor ResearchDiabetes Treatment and Management

Cited by 133

Neuroendocrine Function and Response to Stress in Mice with Complete Disruption of Glucagon-Like Peptide-1 Receptor Signaling1

MacLusky, N. J., Cook, S., Scrocchi, L., Shin, J., Kim, J., Vaccarino, F., Asa, S. L., & Drucker, D. J. (2000) · Endocrinology

Stress Responses and CortisolRegulation of Appetite and Obesity

Cited by 133