Kastner, Philippe

The nuclear receptor superfamily: the second decade

Mangelsdorf, D. J., Thummel, C., Beato, M., Herrlich, P., Schütz, G., Umesono, K., Blumberg, B., Kastner, P., Mark, M., Chambon, P., et al. (1995) · Cell

Estrogen and related hormone effectsNuclear Receptors and Signaling

Cited by 6,964

Two distinct estrogen-regulated promoters generate transcripts encoding the two functionally different human progesterone receptor forms A and B

Kastner, P., Krust, A., Turcotte, B., Stropp, U., Tora, L., Gronemeyer, H., & Chambon, P. (1990) · The EMBO Journal

Estrogen and related hormone effectsGenomics and Chromatin Dynamics

Cited by 1,534

Multiplicity generates diversity in the retinoic acid signalling pathways

Leid, M., Kastner, P., & Chambon, P. (1992) · Trends in Biochemical Sciences

Retinoids in leukemia and cellular processesPeroxisome Proliferator-Activated Receptors

Cited by 821

Stable inhibitory activity of regulatory T cells requires the transcription factor Helios

Kim, H.-J., Barnitz, R. A., Kreslavsky, T., Brown, F. D., Moffett, H., Lemieux, M. E., Kaygusuz, Y., Meissner, T., Holderried, T. A. W., Chan, S., et al. (2015) · Science

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 441

Distinctive and indispensable roles of PU.1 in maintenance of hematopoietic stem cells and their differentiation

Iwasaki, H., Somoza, C., Shigematsu, H., Duprez, E. A., Iwasaki-Arai, J., Mizuno, S.-I., Arinobu, Y., Geary, K., Zhang, P., Dayaram, T., et al. (2005) · Blood

Hematopoietic Stem Cell TransplantationAcute Myeloid Leukemia Research

Cited by 433

Reciprocal activation of GATA-1 and PU.1 marks initial specification of hematopoietic stem cells into myeloerythroid and myelolymphoid lineages

Arinobu, Y., Mizuno, S.-I., Chong, Y., Shigematsu, H., Iino, T., Iwasaki, H., Graf, T., Mayfield, R., Chan, S., Kastner, P., et al. (2007) · Cell Stem Cell

Hematopoietic Stem Cell TransplantationAcute Myeloid Leukemia Research

Cited by 309

PU.1 determines the self-renewal capacity of erythroid progenitor cells

Back, J., Dierich, A., Bronn, C., Kastner, P., & Chan, S. (2004) · Blood

Hematopoietic Stem Cell TransplantationHemoglobinopathies and Related Disorders

Cited by 123

PU.1: A crucial and versatile player in hematopoiesis and leukemia

Kastner, P., & Chan, S. (2008) · The International Journal of Biochemistry & Cell Biology

Hematopoietic Stem Cell TransplantationAcute Myeloid Leukemia Research

Cited by 101

Ikaros is absolutely required for pre-B cell differentiation by attenuating IL-7 signals

Heizmann, B., Kastner, P., & Chan, S. (2013) · Journal of Experimental Medicine

T-cell and B-cell ImmunologyGenomics and Chromatin Dynamics

Cited by 101

Visualizing PU.1 activity during hematopoiesis

Back, J., Allman, D., Chan, S., & Kastner, P. (2005) · Experimental Hematology

Hematopoietic Stem Cell TransplantationGenomics and Chromatin Dynamics

Cited by 97

The Tumor Suppressor Ikaros Shapes the Repertoire of Notch Target Genes in T Cells

Geimer Le Lay, A.-S., Oravecz, A., Mastio, J., Jung, C., Marchal, P., Ebel, C., Dembélé, D., Jost, B., Le Gras, S., Thibault, C., et al. (2014) · Science Signaling

Developmental Biology and Gene RegulationGenomics and Chromatin Dynamics

Cited by 74

Helios represses megakaryocyte priming in hematopoietic stem and progenitor cells

Cova, G., Taroni, C., Deau, M.-C., Cai, Q., Mittelheisser, V., Philipps, M., Jung, M., Cerciat, M., Le Gras, S., Thibault-Carpentier, C., et al. (2021) · Journal of Experimental Medicine

Hematopoietic Stem Cell TransplantationPlatelet Disorders and Treatments

Cited by 17