Caldecott, Keith W.

XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia

Care4Rare Canada Consortium, Hoch, N. C., Hanzlikova, H., Rulten, S. L., Tétreault, M., Komulainen, E., Ju, L., Hornyak, P., Zeng, Z., Gittens, W., et al. (2017) · Nature

DNA Repair MechanismsPARP inhibition in cancer therapy

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RETRACTED: Sealing of Chromosomal DNA Nicks during Nucleotide Excision Repair Requires XRCC1 and DNA Ligase IIIα in a Cell-Cycle-Specific Manner

Moser, J., Kool, H., Giakzidis, I., Caldecott, K., Mullenders, L. H. F., & Fousteri, M. I. (2007) · Molecular Cell

DNA Repair MechanismsNuclear Structure and Function

Cited by 261

Neuronal enhancers are hotspots for DNA single-strand break repair

Wu, W., Kargbo-Hill, S. E., Nathan, W. J., Paiano, J., Callen, E., Wang, D., Shinoda, K., van Wietmarschen, N., Colón-Mercado, J. M., Zong, D., et al. (2021) · Nature

DNA Repair MechanismsPARP inhibition in cancer therapy

Cited by 223

Active DNA demethylation promotes cell fate specification and the DNA damage response

Wang, D., Wu, W., Callen, E., Pavani, R., Zolnerowich, N., Kodali, S., Zong, D., Wong, N., Noriega, S., Nathan, W. J., et al. (2022) · Science

DNA Repair MechanismsEpigenetics and DNA Methylation

Cited by 113

DNA damage and transcription stress

Milano, L., Gautam, A., & Caldecott, K. W. (2024) · Molecular Cell

DNA Repair MechanismsGenomics and Chromatin Dynamics

Cited by 88

Ribose—An Internal Threat to DNA

Caldecott, K. W. (2014) · Science

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 62

Characterization of a novel loss-of-function variant in TDP2 in two adult patients with spinocerebellar ataxia autosomal recessive 23 (SCAR23)

Errichiello, E., Zagnoli-Vieira, G., Rizzi, R., Garavelli, L., Caldecott, K. W., & Zuffardi, O. (2020) · Journal of Human Genetics

Genetic Neurodegenerative DiseasesDNA Repair Mechanisms

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