Cunha, Rodrigo A.

Adenosine receptors and brain diseases: neuroprotection and neurodegeneration

Gomes, C. V., Kaster, M. P., Tomé, A. R., Agostinho, P. M., & Cunha, R. A. (2011) · Biochimica et Biophysica Acta (BBA) - Biomembranes

Adenosine and Purinergic SignalingNeuroscience and Neuropharmacology Research

Cited by 419

Adenosine A2A Receptors Are Essential for Long-Term Potentiation of NMDA-EPSCs at Hippocampal Mossy Fiber Synapses

Rebola, N., Lujan, R., Cunha, R. A., & Mulle, C. (2008) · Neuron

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 376

Caffeine acts through neuronal adenosine A 2A receptors to prevent mood and memory dysfunction triggered by chronic stress

Kaster, M. P., Machado, N. J., Silva, H. B., Nunes, A., Ardais, A. P., Santana, M., Baqi, Y., Müller, C. E., Rodrigues, A. L. S., Porciúncula, L. O., et al. (2015) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchStress Responses and Cortisol

Cited by 312

Adenosine receptor antagonists including caffeine alter fetal brain development in mice

Silva, C. G., Métin, C., Fazeli, W., Machado, N. J., Darmopil, S., Launay, P.-S., Ghestem, A., Nesa, M.-P., Bassot, E., Szabó, E., et al. (2013) · Science Translational Medicine

Neurogenesis and neuroplasticity mechanismsAnesthesia and Neurotoxicity Research

Cited by 177

Deletion of Adenosine A2A Receptors From Astrocytes Disrupts Glutamate Homeostasis Leading to Psychomotor and Cognitive Impairment: Relevance to Schizophrenia

Matos, M., Shen, H.-Y., Augusto, E., Wang, Y., Wei, C. J., Wang, Y. T., Agostinho, P., Boison, D., Cunha, R. A., & Chen, J.-F. (2015) · Biological Psychiatry

Schizophrenia research and treatmentNeuroscience and Neuropharmacology Research

Cited by 153

Caffeine, Adenosine Receptors, and Synaptic Plasticity

Costenla, A. R., Cunha, R. A., & de Mendonça, A. (2010) · Journal of Alzheimer's Disease

Neuroscience and Neuropharmacology ResearchAdenosine and Purinergic Signaling

Cited by 132

Caffeine Consumption Prevents Diabetes-Induced Memory Impairment and Synaptotoxicity in the Hippocampus of NONcZNO10/LTJ Mice

Duarte, J. M. N., Agostinho, P. M., Carvalho, R. A., & Cunha, R. A. (2012) · PLoS ONE

Coffee research and impactsNeuroscience and Neuropharmacology Research

Cited by 130

Caffeine Regulates Frontocorticostriatal Dopamine Transporter Density and Improves Attention and Cognitive Deficits in an Animal Model of Attention Deficit Hyperactivity Disorder

Pandolfo, P., Machado, N. J., Köfalvi, A., Takahashi, R. N., & Cunha, R. A. (2013) · European Neuropsychopharmacology

Attention Deficit Hyperactivity DisorderNeurotransmitter Receptor Influence on Behavior

Cited by 118

Increased density and synapto-protective effect of adenosine A2A receptors upon sub-chronic restraint stress

Cunha, G. M. A., Canas, P. M., Oliveira, C. R., & Cunha, R. A. (2006) · Neuroscience

Adenosine and Purinergic SignalingStress Responses and Cortisol

Cited by 108

Overexpression of Adenosine A2A Receptors in Rats: Effects on Depression, Locomotion, and Anxiety

Coelho, J. E., Alves, P., Canas, P. M., Valadas, J. S., Shmidt, T., Batalha, V. L., Ferreira, D. G., Ribeiro, J. A., Bader, M., Cunha, R. A., et al. (2014) · Frontiers in Psychiatry

Neurotransmitter Receptor Influence on BehaviorAdenosine and Purinergic Signaling

Cited by 102

Selective A2A receptor antagonist prevents microglia-mediated neuroinflammation and protects retinal ganglion cells from high intraocular pressure–induced transient ischemic injury

Madeira, M. H., Boia, R., Elvas, F., Martins, T., Cunha, R. A., Ambrósio, A. F., & Santiago, A. R. (2016) · Translational Research

Glaucoma and retinal disordersNeuroinflammation and Neurodegeneration Mechanisms

Cited by 83

Lateral septum adenosine A2A receptors control stress-induced depressive-like behaviors via signaling to the hypothalamus and habenula

Wang, M., Li, P., Li, Z., da Silva, B. S., Zheng, W., Xiang, Z., He, Y., Xu, T., Cordeiro, C., Deng, L., et al. (2023) · Nature Communications

Neurotransmitter Receptor Influence on BehaviorTreatment of Major Depression

Cited by 73

Repeated cycles of binge-like ethanol exposure induce immediate and delayed neurobehavioral changes and hippocampal dysfunction in adolescent female rats

Fernandes, L. M. P., Cartágenes, S. C., Barros, M. A., Carvalheiro, T. C. V. S., Castro, N. C. F., Schamne, M. G., Lima, R. R., Prediger, R. D., Monteiro, M. C., Fontes-Júnior, E. A., et al. (2018) · Behavioural Brain Research

Prenatal Substance Exposure EffectsNeuroscience and Neuropharmacology Research

Cited by 46

Caffeine and cannabinoid receptors modulate impulsive behavior in an animal model of attentional deficit and hyperactivity disorder

Leffa, D. T., Ferreira, S. G., Machado, N. J., Souza, C. M., Rosa, F. D., de Carvalho, C., Kincheski, G. C., Takahashi, R. N., Porciúncula, L. O., Souza, D. O., et al. (2019) · European Journal of Neuroscience

Cannabis and Cannabinoid ResearchAttention Deficit Hyperactivity Disorder

Cited by 39

Electrophysiological and Immunocytochemical Evidence for P2X Purinergic Receptors in Pancreatic β Cells

Silva, A. M., Rodrigues, R. J., Tomé, Â. R., Cunha, R. A., Misler, S., Rosário, L. M., & Santos, R. M. (2008) · Pancreas

Adenosine and Purinergic SignalingPancreatic function and diabetes

Cited by 35