Beutler, Bruce

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

Poltorak, A., He, X., Smirnova, I., Liu, M.-Y., Huffel, C. V., Du, X., Birdwell, D., Alejos, E., Silva, M., Galanos, C., et al. (1998) · Science

Immune Response and InflammationInflammasome and immune disorders

Cited by 7,631

Shock and Tissue Injury Induced by Recombinant Human Cachectin

Tracey, K. J., Beutler, B., Lowry, S. F., Merryweather, J., Wolpe, S., Milsark, I. W., Hariri, R. J., Fahey, T. J., Zentella, A., Albert, J. D., et al. (1986) · Science

Sepsis Diagnosis and TreatmentImmune Response and Inflammation

Cited by 2,549

Tumor necrosis factor (cachectin) is an endogenous pyrogen and induces production of interleukin 1.

Dinarello, C. A., Cannon, J. G., Wolff, S. M., Bernheim, H. A., Beutler, B., Cerami, A., Figari, I. S., Palladino, M. A., & O'Connor, J. V. (1986) · The Journal of experimental medicine

Immune Response and InflammationThermal Regulation in Medicine

Cited by 1,472

CD36 is a sensor of diacylglycerides

Hoebe, K., Georgel, P., Rutschmann, S., Du, X., Mudd, S., Crozat, K., Sovath, S., Shamel, L., Hartung, T., Zähringer, U., et al. (2005) · Nature

Immune Response and InflammationInflammasome and immune disorders

Cited by 873

TLRs and innate immunity

Beutler, B. A. (2009) · Blood

Immune Response and InflammationInflammasome and immune disorders

Cited by 840

The serine protease TMPRSS6 is required to sense iron deficiency

Du, X., She, E., Gelbart, T., Truksa, J., Lee, P., Xia, Y., Khovananth, K., Mudd, S., Mann, N., Moresco, E. M. Y., et al. (2008) · Science

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 578

Toll-like receptors

Moresco, E. M. Y., LaVine, D., & Beutler, B. (2011) · Current Biology

Immune Response and InflammationInvertebrate Immune Response Mechanisms

Cited by 500

PU.1 and Interferon Consensus Sequence-binding Protein Regulate the Myeloid Expression of the Human Toll-like Receptor 4 Gene

Rehli, M., Poltorak, A., Schwarzfischer, L., Krause, S. W., Andreesen, R., & Beutler, B. (2000) · Journal of Biological Chemistry

Immune Response and InflammationGenomics and Chromatin Dynamics

Cited by 233

Evolution of the genome and the genetic code: selection at the dinucleotide level by methylation and polyribonucleotide cleavage

Beutler, E., Gelbart, T., Han, J. H., Koziol, J. A., & Beutler, B. (1989) · Proceedings of the National Academy of Sciences

RNA and protein synthesis mechanismsDNA and Nucleic Acid Chemistry

Cited by 189